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ICON

Senior Clinical Research Associate

Knoxville, TN · On-site +1

Senior Clinical Research Associate - Oncology - Knoxville, TN ICON is a global healthcare ... Maintain up-to-date documentation in CTMS and eTMF systems * Support and track site staff training ...

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Infographic showing various Associate Etmf job openings in Tennessee as of August 2026, with employment types broken down into 1% As Needed, 71% Full Time, 25% Part Time, 1% Temporary, and 2% Contract. Highlights an 96% Physical, 1% Hybrid, and 3% Remote job distribution.

Senior Clinical Research Associate

ICON

Knoxville, TN • On-site, Remote

Full-time

Medical, Dental, Vision, Life, Retirement

Re-posted 12 days ago

Job description

Senior Clinical Research Associate - Oncology - Knoxville, TN
ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.
As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.
What You Will Be Doing:
  • Serve as the primary point of contact between investigational sites and the sponsor
  • Conduct all types of site visits, including selection, initiation, routine monitoring, and close-out
  • Ensure site compliance with ICH-GCP, SOPs, and regulations
  • Maintain up-to-date documentation in CTMS and eTMF systems
  • Support and track site staff training and maintain compliance records
  • Monitor patient safety, ensuring timely and accurate AE/SAE/PQC reporting
  • Support subject recruitment and retention efforts at the site level
  • Oversee drug accountability and ensure proper storage, return, or destruction
  • Resolve data queries and drive timely, high-quality data entry
  • Document site progress and escalate risks or issues to the clinical team
  • Assist in tracking site budgets and ensuring timely site payments (as applicable)
  • Collaborate with cross-functional partners including CTAs, LTMs, and CTMs

You are:
  • A graduate with a Bachelor's degree in Life Sciences or equivalent, or a qualified RN
  • Eligible to work in United States without visa sponsorship
  • A clinical research professional with 3+ years of on-site monitoring experience in the pharmaceutical or CRO industry
  • Experienced monitoring Oncology (i.e. Prostate Cancer, and Lung Cancer) and/or Hematology oncology trials
  • Proficient in ICH-GCP, local regulatory requirements, and clinical systems like CTMS and eTMF
  • A clear communicator, problem-solver, and collaborative team player
  • Willing and able to travel up to 50% for on-site monitoring visits across southeast region; preference given to candidates residing in TN or KY near major HUB airports to support efficient regional travel

Employment with ICON is contingent upon having the legal right to work in the country where the role is based.
Rewards & Benefits
ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.
Benefits may include:
  • Competitive base salary and performance related incentives
  • Health and wellbeing programmes including medical, dental, and vision coverage where applicable
  • Retirement and pension plans
  • Life assurance and disability coverage
  • Employee assistance programmes and wellbeing resources
  • Learning and development opportunities through structured training and career pathways

Benefits may vary depending on role and location.
Visit our careers site to read more about the benefits ICON offers.
Inclusion and Accessibility
ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.
If you require reasonable accommodations during the recruitment process, please let us know or submit a request here.
Are you a current ICON Employee? Please click here to apply

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