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Associate Downstream Processing Scientist Jobs in Frederick, MD

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Downstream GMP Manufacturing Associate / BMA Upstream I & II

Rockville, MD · On-site

$23 - $28/hr

High School Diploma or Associate Degree with 0-2 years of experience in Downstream biologic production processes in a GMP environment in a Life Sciences Company; or Bachelor of Science in science or ...

TAMKO

Manufacturing Data Scientist

Frederick, MD

As part of a cross-functional Business Process Transformation team, you will design, build, and ... to downstream models and AI systems. * Design and build end-to-end, multi-agent solutions that ...

Merck Group

Associate Scientist 3

Rockville, MD · On-site

$28 - $44/hr

As an Associate Scientist 3 your activities will support assay development through commercial ... processes and equipment. * May serve as a team lead * Assumes roles on more complex team projects.

Kaigene, Inc

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Scientist (Protein Expression and Purification)

Rockville, MD · On-site

$60K - $80K/yr

We are seeking a highly motivated and experienced scientist to join our protein engineering team ... for downstream characterization and analysis. * Collaborative with cross-functional teams to ...

Kaigene, Inc

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Scientist (Protein Expression and Purification)

Rockville, MD · On-site

$60K - $80K/yr

We are seeking a highly motivated and experienced scientist to join our protein engineering team ... for downstream characterization and analysis. * Collaborative with cross-functional teams to ...

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All JobsAssociate Downstream Processing Scientist JobsAssociate Downstream Processing Scientist Jobs in Frederick, MD

Associate Downstream Processing Scientist information

See Frederick, MD salary details

$18

$35

$57

How much do associate downstream processing scientist jobs pay per hour?

As of Aug 29, 2026, the average hourly pay for associate downstream processing scientist in Frederick, MD is $35.72, according to ZipRecruiter salary data. Most workers in this role earn between $27.74 and $40.62 per hour, depending on experience, location, and employer.

What is the difference between Associate Downstream Processing Scientist vs Associate Upstream Processing Scientist?

AspectAssociate Downstream Processing ScientistAssociate Upstream Processing Scientist
Primary FocusPurification and recovery of bioproductsCell culture and fermentation processes
Skills & CertificationsProtein purification, chromatography, GMP complianceCell culture, bioreactor operation, aseptic techniques
Work EnvironmentLaboratories, manufacturing facilitiesBioreactors, cell culture labs
Industry UsageBiotech, pharmaceutical manufacturingBiotech, pharmaceutical research and production

Both roles are essential in biopharmaceutical production, with the Associate Downstream Processing Scientist focusing on purification processes, while the Associate Upstream Processing Scientist handles cell growth and fermentation. They often collaborate within the same production pipeline, but their skill sets and daily tasks differ based on their specific focus areas.

What are the most commonly searched types of Downstream Processing Scientist jobs in Frederick, MD?

The most popular types of Downstream Processing Scientist jobs in Frederick, MD are:

What are popular job titles related to Associate Downstream Processing Scientist jobs in Frederick, MD?

For Associate Downstream Processing Scientist jobs in Frederick, MD, the most frequently searched job titles are:

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What cities near Frederick, MD are hiring for Associate Downstream Processing Scientist jobs?

Cities near Frederick, MD with the most Associate Downstream Processing Scientist job openings:

Associate Downstream Processing Scientist jobs near you
Infographic showing various Associate Downstream Processing Scientist job openings in Frederick, MD as of August 2026, with employment types broken down into 1% As Needed, 67% Full Time, 30% Part Time, 1% Temporary, and 1% Contract. Highlights an 96% Physical, 1% Hybrid, and 3% Remote job distribution, with an average salary of $74,295 per year, or $35.7 per hour.

Sr. Scientist (Downstream Process Development)

Kelly Services

Gaithersburg, MD • On-site

Full-time, Contractor

Medical, Dental, Vision, Life, Retirement, PTO

Posted 28 days ago

Job description

Kelly Government Solutions is a strategic supplier and business partner to the federal government and its key suppliers.  Through our partnership with the National Institutes of Health, Kelly Government Solutions offers administrative, IT, engineering, scientific, and healthcare professionals the opportunity to work with the leading medical research center in the world.  We have an opening for a Senior Scientist (Downstream Process Development) to work on-site at the National Institutes of Health (NIH) in Gaithersburg, MD.
This is a long-term contract position which offers:
-    Competitive compensation and comprehensive benefit package
-    Optional health, vision, and dental plans
-    Paid leave as well as 11 paid federal holidays and 401K plan.  
-    Access to NIH’s unparalleled resources and niche scientific initiatives
KEY TASKS
(1) Oversee the development of downstream processes for clinical candidates and the process of tech transfer for clinical material generation
(2) Provide project support to develop downstream process methods that meet the product quality and recovery characteristics to guarantee successful production of clinical material.
(3) Serve as a subject matter expert (SME) in guiding purification strategies for new vaccine or therapeutic mAb candidates 
(4) Work with regulatory team to support IND submissions and other requests. 
(5) Oversee viral clearance strategies in relevant downstream processes and direct the viral clearance validation efforts 
(6) Plan and oversee downstream processes for toxicology lot material production. 
(7) Coordinate with manufacturing teams to ensure timely and scale-appropriate Technology Transfer is achieved
(8) Write/edit/review tech transfer documents to support downstream process Master Batch Record authoring.
(9) Serve as SME in downstream troubleshooting and facility fit calculations. 
(10) Serve as the Center’s downstream SME in external collaborations for clinical development projects
(11) Work to troubleshoot and improve downstream methods during the development cycle. This includes efforts in designing optimization studies (DOE with JMP) and streamlining efforts to ensure timely development schedules
REQUIREMENTS
(1) Ph.D. in Bioengineering, Chemical Engineering, Biochemistry, or a related field
(2) Minimum of 8 years of relevant experience with recombinant protein purification development for GMP clinical-phase products
PLEASE APPLY ONLINE
When you apply, please know a Kelly Government Solutions Recruiter will review your resume and will contact you directly, if your skills and experience match the requirements of this position; a full job description can be made available at that time.
Due to the high volume of inquiries, we regret that we cannot accept phone calls. Even if you aren’t contacted for this position, you are still part of our talent network.  All Kelly recruiters have access to your profile, which expands your opportunities even further.
As part of our promise to talent, Kelly supports those who work with us through a variety of benefits, perks, and work-related resources. Kelly offers eligible employees voluntary benefit plans including medical, dental, vision, telemedicine, term life, whole life, accident insurance, critical illness, short-term disability, and a transportation spending account. In addition, this position offers employees the ability to earn up to 160 hours of paid time off annually and eleven paid holidays per benefit year. We also offer a generous defined 401(k) contribution to help you save for retirement. Visit https://www.mykelly.us/us-mykelly/perks/ for more information on benefits and perks that may be available to you as a member of the Kelly Talent Community.
#government
As part of our promise to talent, Kelly supports those who work with us through a variety of benefits, perks, and work-related resources. Kelly offers eligible employees voluntary benefit plans including medical, dental, vision, telemedicine, term life, whole life, accident insurance, critical illness, a legal plan, and short-term disability. As a Kelly employee, you will have access to a retirement savings plan, service bonus and holiday pay plans (earn up to eight paid holidays per benefit year), and a transit spending account. In addition, employees are entitled to earn paid sick leave under the applicable state or local plan. Click here for more information on benefits and perks that may be available to you as a member of the Kelly Talent Community.

Why Kelly® Government Solutions?

Looking to connect with premier government agencies or the top 25 federal government contractors? Kelly Government Solutions partners with these organizations to create expert talent solutions that solve the world’s most critical challenges. We offer a variety of full-time, project (SOW), seasonal, and surge support opportunities in science, engineering, technology, professional, and administrative support roles. Our experts will connect you to the opportunity that fits your schedule and interests and handle the details of transferring and processing all levels of security clearances. It’s just another way we make the job search work for you.

About Kelly

Work changes everything. And at Kelly, we’re obsessed with where it can take you. To us, it’s about more than simply accepting your next job opportunity. It’s the fuel that powers every next step of your life. It’s the ripple effect that changes and improves everything for your family, your community, and the world. Which is why, here at Kelly, we are dedicated to providing you with limitless opportunities to enrich your life-just ask the 300,000 people we employ each year.
Kelly is committed to providing equal employment opportunities to all qualified employees and applicants regardless of race, color, sex, sexual orientation, gender identity, religion, national origin, disability, veteran status, age, marital status, pregnancy, genetic information, or any other legally protected status, and we take affirmative action to recruit, employ, and advance qualified individuals with disabilities and protected veterans in the workforce. Requests for accommodation related to our application process can be directed to the Kelly Human Resource Knowledge Center. Kelly complies with the requirements of California’s state and local Fair Chance laws. A conviction does not automatically bar individuals from employment. Kelly participates in E-Verify and will provide the federal government with your Form I-9 information to confirm that you are authorized to work in the U.S.
Kelly may use AI-powered tools during the recruitment and hiring process. For full details, including how Kelly uses AI, your rights, and how to request a reasonable accommodation, visit the Recruitment Artificial Intelligence Notice.