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Associate Downstream Process Development Scientist Jobs in Middleton, WI

Promega

Sr Research Scientist 1

Madison, WI · On-site

$99K - $126K/yr

OUR TEAM: Our team of R&D scientists develops and commercializes platform technologies for ... to downstream computational and AI-driven analysis; provide scientific leadership in these areas ...

Promega

Sr Research Scientist 1

Madison, WI · On-site

$99K - $126K/yr

OUR TEAM: Our team of R&D scientists develops and commercializes platform technologies for ... to downstream computational and AI-driven analysis; provide scientific leadership in these areas ...

Promega

Sr Research Scientist 1

Madison, WI · On-site

$99K - $126K/yr

OUR TEAM: Our team of R&D scientists develops and commercializes platform technologies for ... to downstream computational and AI-driven analysis; provide scientific leadership in these areas ...

Techtrueup

Manufacturing Engineer

Madison, WI · On-site

$73K - $94K/yr

Work with Manufacturing, Process Development, QA, QC, Supply Chain, Facilities, and other teams ... Work with upstream, downstream, and/or molecular therapeutics processes . * Provide technical ...

New

Techtrueup

Manufacturing Engineer

Madison, WI · On-site

$73K - $94K/yr

Work with Manufacturing, Process Development, QA, QC, Supply Chain, Facilities, and other teams ... Work with upstream, downstream, and/or molecular therapeutics processes . * Provide technical ...

New

Techtrueup

Manufacturing Engineer

Madison, WI · On-site

$73K - $94K/yr

Work with Manufacturing, Process Development, QA, QC, Supply Chain, Facilities, and other teams ... Work with upstream, downstream, and/or molecular therapeutics processes . * Provide technical ...

New

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All JobsAssociate Downstream Process Development Scientist JobsAssociate Downstream Process Development Scientist Jobs in Middleton, WI

Associate Downstream Process Development Scientist information

See Middleton, WI salary details

$19

$33

$49

How much do associate downstream process development scientist jobs pay per hour?

As of Sep 14, 2026, the average hourly pay for associate downstream process development scientist in Middleton, WI is $33.80, according to ZipRecruiter salary data. Most workers in this role earn between $27.74 and $41.49 per hour, depending on experience, location, and employer.

What is an associate downstream process development scientist?

An Associate Downstream Process Development Scientist is a professional who works in the biotechnology or pharmaceutical industry, focusing on developing and optimizing processes that purify biological products, such as proteins or antibodies, after they have been produced by cells. Their work is crucial for ensuring the final product meets quality and safety standards before it is used in research or clinical applications. They typically perform laboratory experiments, analyze data, and collaborate with other scientists and engineers to improve yield and efficiency. This role is often entry-level or early-career, providing hands-on experience in process development and technical troubleshooting.

What are some typical challenges faced by an associate downstream process development scientist, and how can they be addressed?

Associate Downstream Process Development Scientists often encounter challenges such as optimizing purification processes, troubleshooting equipment performance, and ensuring batch-to-batch consistency. These challenges can be addressed by maintaining meticulous documentation, collaborating closely with upstream and analytical teams, and staying current with best practices in chromatography and filtration. Proactively seeking feedback from experienced colleagues and participating in cross-functional meetings can also help in identifying solutions and improving process efficiency.

What are the key skills and qualifications needed to thrive as an associate downstream process development scientist, and why are they important?

To excel as an Associate Downstream Process Development Scientist, you need a solid understanding of biochemistry, chemical engineering, and downstream purification techniques, often supported by a bachelor's or master's degree in a life science or engineering discipline. Familiarity with chromatographic systems (such as AKTA), filtration equipment, and analytical tools, as well as knowledge of GMP/GLP regulations, is typically required. Strong problem-solving, attention to detail, and effective teamwork and communication skills help you navigate complex experiments and collaborate with cross-functional teams. These skills ensure efficient process optimization, compliance with regulatory standards, and successful development of biopharmaceutical products.

What is the difference between Associate Downstream Process Development Scientist vs Associate Upstream Process Development Scientist?

AspectAssociate Downstream Process Development ScientistAssociate Upstream Process Development Scientist
Primary FocusPurification and recovery of bioproductsCell culture and fermentation processes
Required SkillsProtein purification, chromatography, filtrationCell culture, bioreactor operation, media preparation
Work EnvironmentLaboratories, manufacturing facilitiesLaboratories, bioreactor labs
Common CertificationsBiotech or bioprocessing certificationsBiotech or bioprocessing certifications

Both roles are essential in biopharmaceutical development, focusing on different stages of the production process. The Associate Downstream Process Development Scientist specializes in purification techniques, while the Associate Upstream Process Development Scientist concentrates on cell growth and fermentation. Understanding these distinctions helps candidates target their skills and career paths effectively.

Associate Downstream Process Development Scientist jobs near you
Infographic showing various Associate Downstream Process Development Scientist job openings in Middleton, WI as of August 2026, with employment types broken down into 100% Full Time. Highlights an 75% In-person, and 25% Remote job distribution, with an average salary of $70,309 per year, or $33.8 per hour.

Senior Scientist I, Analytical Development

Madison, WI • On-site

Scorpion Therapeutics
51 - 200 employees
Learn more about Scorpion Therapeuticsexternal

$115K - $135K/yr

Other

Posted 15 days ago

Job description

Responsibilities:
  • Work independently and collaboratively with project teams to deliver accurate, high-quality analytical results.
  • Provide technical leadership, guidance, and mentorship to junior scientists.
  • Serve as Analytical Project Coordinator or Lead; take ownership of analytical activities (planning, prioritizing, coordinating testing to meet timelines).
  • Independently design, develop, optimize, and validate analytical methods for drug substance/API and drug product development.
  • Develop specifications and test methods for raw materials, in-process materials, intermediates, drug substances, and drug products.
  • Lead analytical activities supporting process development, impurity characterization, GLP toxicology studies, and cGMP clinical trial materials.
  • Analyze/interprete complex data, troubleshoot technical challenges, and recommend follow-up activities.
  • Prepare/review technical documentation (test methods, development/validation protocols and reports, SOPs, presentations).
  • Communicate status, results, risks, and recommendations to project teams and management.
  • Ensure work is performed per SOPs, cGMP requirements, regulatory guidelines, and industry standards.
  • Contribute to continuous improvement; perform other duties as assigned.
Requirements:
  • Ph.D. (2+ yrs), M.S. (10+ yrs), or B.S. (12+ yrs) in Chemistry or related field.
  • Analytical method development, optimization, qualification, and validation for pharmaceutical drug substance and drug product.
  • Experience developing analytical methods/specifications for raw materials, intermediates, drug substances, and drug products.
  • Proficiency with instrumentation/techniques: HPLC, GC, FTIR, UV/Vis, LC/MS, Karl Fischer (KF).
  • Strong knowledge of instrumentation principles, test methodologies, and method validation.
  • Strong understanding of CMC regulatory requirements and applicable cGMP, ICH, and FDA/CDER guidelines.
  • Knowledge of synthetic organic chemistry principles; strong judgment, problem-solving, data interpretation.
  • Excellent organizational skills, communication, attention to detail, data quality/integrity; ability to work independently and cross-functionally.
  • Candidates must have current, valid authorization to work in the country where this role is located.
Preferred:
  • Experience mentoring/training junior scientists.
  • Experience serving as analytical project lead/coordinator.
  • Experience supporting analytical activities across multiple stages of drug development.
  • Demonstrated ability to influence scientific direction and communicate technical recommendations.
Benefits/Pay:
  • Wisconsin pay range: $115,000 USD - $135,000 USD.
  • Competitive salaries and an excellent benefit package.
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