1

Associate Downstream Process Development Scientist Jobs in Tennessee

Role Profile We are seeking a highly commercial, customer-facing Business Development Manager to ... Experience navigating long, matrixed downstream buying processes in packaging, coatings, adhesives ...

Role Profile We are seeking a highly commercial, customer-facing Business Development Manager to ... Experience navigating long, matrixed downstream buying processes in packaging, coatings, adhesives ...

Partner with Graphic Artists on catalog creation and development for assigned categories, providing ... company process. * Contribute to weekly and quarterly product claims reporting for assigned ...

next page

Showing results 1-20

Associate Downstream Process Development Scientist information

What is an Associate Downstream Process Development Scientist?

An Associate Downstream Process Development Scientist is a professional who works in the biotechnology or pharmaceutical industry, focusing on developing and optimizing processes that purify biological products, such as proteins or antibodies, after they have been produced by cells. Their work is crucial for ensuring the final product meets quality and safety standards before it is used in research or clinical applications. They typically perform laboratory experiments, analyze data, and collaborate with other scientists and engineers to improve yield and efficiency. This role is often entry-level or early-career, providing hands-on experience in process development and technical troubleshooting.

What are the key skills and qualifications needed to thrive as an Associate Downstream Process Development Scientist, and why are they important?

To excel as an Associate Downstream Process Development Scientist, you need a solid understanding of biochemistry, chemical engineering, and downstream purification techniques, often supported by a bachelor's or master's degree in a life science or engineering discipline. Familiarity with chromatographic systems (such as AKTA), filtration equipment, and analytical tools, as well as knowledge of GMP/GLP regulations, is typically required. Strong problem-solving, attention to detail, and effective teamwork and communication skills help you navigate complex experiments and collaborate with cross-functional teams. These skills ensure efficient process optimization, compliance with regulatory standards, and successful development of biopharmaceutical products.

What is the difference between Associate Downstream Process Development Scientist vs Associate Upstream Process Development Scientist?

AspectAssociate Downstream Process Development ScientistAssociate Upstream Process Development Scientist
Primary FocusPurification and recovery of bioproductsCell culture and fermentation processes
Required SkillsProtein purification, chromatography, filtrationCell culture, bioreactor operation, media preparation
Work EnvironmentLaboratories, manufacturing facilitiesLaboratories, bioreactor labs
Common CertificationsBiotech or bioprocessing certificationsBiotech or bioprocessing certifications

Both roles are essential in biopharmaceutical development, focusing on different stages of the production process. The Associate Downstream Process Development Scientist specializes in purification techniques, while the Associate Upstream Process Development Scientist concentrates on cell growth and fermentation. Understanding these distinctions helps candidates target their skills and career paths effectively.

What are some typical challenges faced by an Associate Downstream Process Development Scientist, and how can they be addressed?

Associate Downstream Process Development Scientists often encounter challenges such as optimizing purification processes, troubleshooting equipment performance, and ensuring batch-to-batch consistency. These challenges can be addressed by maintaining meticulous documentation, collaborating closely with upstream and analytical teams, and staying current with best practices in chromatography and filtration. Proactively seeking feedback from experienced colleagues and participating in cross-functional meetings can also help in identifying solutions and improving process efficiency.
What are the most commonly searched types of Downstream Process Development Scientist jobs in Tennessee? The most popular types of Downstream Process Development Scientist jobs in Tennessee are:
What cities in Tennessee are hiring for Associate Downstream Process Development Scientist jobs? Cities in Tennessee with the most Associate Downstream Process Development Scientist job openings:
Associate Applications Scientist

Associate Applications Scientist

Eastman

Kingsport, TN

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 23 days ago


Eastman Chemical rating

8.4

Company rating: 8.4 out of 10

Based on 66 frontline employees who took The Breakroom Quiz

23rd of 92 rated chemical manufacturers


Job description

Founded in 1920, Eastman is a global specialty materials company that produces a broad range of products found in items people use every day. With the purpose of enhancing the quality of life in a material way, Eastman works with customers to deliver innovative products and solutions while maintaining a commitment to safety and sustainability. The company’s innovation-driven growth model takes advantage of world-class technology platforms, deep customer engagement, and differentiated application development to grow its leading positions in attractive end markets such as transportation, building and construction, and consumables. As a globally inclusive company, Eastman employs approximately 13,000 people around the world and serves customers in more than 100 countries. The company had 2025 revenue of approximately $8.8 billion and is headquartered in Kingsport, Tennessee, USA. For more information, visit www.eastman.com.

Description

Eastman Chemical Company is seeking an experienced Applications Development / Research Scientist to advance the Aventa™ biodegradable polymers product family through product development, compounding and scale-up of novel cellulose ester-based formulations.  Utilizing a fundamental, science‑first approach, the role emphasizes rigorous investigation of melt rheology, chain architecture, phase behavior, and degradation pathways to build predictive structure–property–processing maps that guide formulation and processing decisions. The scientist will translate these fundamentals into robust, safe, and repeatable processing solutions across extrusion, profile extrusion, and injection molding while meeting end‑use fitness‑for‑use (FFU) and home/industrial compostability targetsat optimized cost.  This position reports into the Biodegradable Technology Division and is located at the R&D headquarters in Kingsport, TN.

Responsibilities
  • Participate in, align with, and influence Eastman’s market segment team strategy (Application Development, Product Development, Marketing, Sales, Technical Service, Product Management, Regulatory, Manufacturing).
  • Translate customer and market needs into technical requirements and Critical to Quality (CTQ) metrics to guide product concepts and product selection.
  • Lead and support market-facing Stage Gate projects; define technical milestones, risks and mitigation plans.
  • Design and execute application- and formulation-specific experiments to develop fundamental understanding of melt rheology and relate rheological metrics to processing performance and end-use properties.
  • Formulate and compound cellulose ester polymer blends and additive systems to meet targeted rheology, mechanical, optical and compostability requirements; optimize cost/performance trade-offs.
  • Run, interpret and apply rheometry, MFI/MI, melt strength and processability tests; translate results to processing windows and machine settings.
  • Design and analyze DOE and statistical studies to optimize formulations and process parameters.
  • Support lab, pilot and scale up compounding/extrusion trials; troubleshoot processing challenges and recommend robust, safe operating conditions.
  • Facilitate and run customer trials and internal validations; communicate results and convert validated trials into product development actions.
  • Create and protect innovative solutions via patent disclosures and support intellectual property activities.
  • Prepare clear technical documentation and oral presentations for internal and external stakeholders (test reports, technical data sheets, regulatory inputs).
  • Apply and promote rigorous safety and environmental practices: lead hazard assessments, ensure compliant handling and disposal of materials, and support other safety programs.
Qualifications
  • Doctoral degree in Polymer Science/Engineering, Materials Science, Chemical Engineering, or related technical field required.
  • 5+ years industry experience translating polymer formulation fundamentals into commercial scale products highly preferred. 
  • Demonstrated hands on experience with melt rheology testing and interpretation.
  • Practical experience in formulation, compounding and extrusion (lab and pilot scale).
  • Strong understanding of polymer structure–property relationships and how formulation and processing influence end use properties and compostability.
  • Experience designing and analyzing DOE and applying statistics to drive formulation/process decisions.
  • Excellent written and verbal communication skills; ability to present technical results to cross functional teams and customers.
  • Proven commitment to safety and environmental compliance.

PREFERRED QUALIFICATIONS (NOT REQUIRED)

  • Experience in design, processability, and structure-properties of cellulose esters.
  • Hands on experience with injection molding, profile extrusion, thermoforming and pilot scale extrusion.
  • Experience developing compostable polymer formulations and familiarity with standards (e.g., ASTM D6400, EN 13432, or equivalent).
  • Hands on experience with injection molding, profile extrusion, thermoforming and pilot scale extrusion. Especially preferred for cellulose ester polymers.
  • Familiarity with polymer analytics: GPC/SEC, DSC, TGA, DMA, FTIR, tensile/impact testing.
  • Experience with rheology modeling or predictive tools (e.g., RheoWin, MATLAB) and with data tools (JMP, Python desirable).
  • Track record of patent filings or published technical reports related to polymer formulations or rheology.
  • Experience running customer application trials and translating feedback into product designs.

OTHER INFORMATION

Location: Kingsport, TN — primarily onsite (laboratory and pilot work).

Benefits

Your total rewards go far beyond a competitive salary. When you join Eastman, you gain access to an exceptional suite of programs designed to protect your health, grow your wealth, and fuel your career.

Compensation & Incentives
• Base pay plus performance-based incentive opportunities that let you share in our success.

Health & Wellness
• Comprehensive medical, prescription-drug, and dental coverage—paired with a Health Savings Account option to help you save tax-free dollars for care today or in the future.
• A robust menu of voluntary benefits—including vision, optional life, critical-illness protection, and more—so you can tailor coverage to fit your life.
• Holistic wellness support: financial-planning tools, family-building assistance (adoption, pregnancy, and fertility resources), parental leave, and confidential Employee Assistance Program counseling.

Retirement & Financial Strategies
• 401(k) with a company match—plus an additional annual retirement contribution from Eastman to accelerate your long-term savings.

Time Away
• Eleven paid holidays, one personal day, paid time off, and paid vacation to recharge, celebrate, or handle life’s moments.

Growth & Development
• Access to mentorship, learning resources, and leadership programs that empower you to thrive in your current role and chart the next steps in your career.

At Eastman, we invest in the whole you—so you can bring your best self to work every day and build a future you’re proud of.

Eastman Chemical Company is an equal opportunity employer.  All qualified applicants will receive consideration for employment without regard to age, race, color, religion, sex, sexual orientation, gender identity, national origin, disability, pregnancy, veteran status or any other protected classes as designated by law.

Eastman is committed to creating a powerfully engaged workplace, where everyone can contribute to their fullest potential each day.


What Eastman Chemical employees say

Pay

Benefits

Hours and flexibility

Workplace

Get the full story on Breakroom