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Associate Downstream Process Development Scientist Jobs in Missouri

In Biologics at Thermo Fisher Scientific we deliver, from process development through commercial ... Provides strong technical leadership to process engineers, scientists and associates for clinical ...

Working in a highly collaborative and science-driven environment, you will engage with executive ... downstream processing, process development, technology transfer, analytical development, GMP ...

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Associate Downstream Process Development Scientist information

What is an Associate Downstream Process Development Scientist?

An Associate Downstream Process Development Scientist is a professional who works in the biotechnology or pharmaceutical industry, focusing on developing and optimizing processes that purify biological products, such as proteins or antibodies, after they have been produced by cells. Their work is crucial for ensuring the final product meets quality and safety standards before it is used in research or clinical applications. They typically perform laboratory experiments, analyze data, and collaborate with other scientists and engineers to improve yield and efficiency. This role is often entry-level or early-career, providing hands-on experience in process development and technical troubleshooting.

What are the key skills and qualifications needed to thrive as an Associate Downstream Process Development Scientist, and why are they important?

To excel as an Associate Downstream Process Development Scientist, you need a solid understanding of biochemistry, chemical engineering, and downstream purification techniques, often supported by a bachelor's or master's degree in a life science or engineering discipline. Familiarity with chromatographic systems (such as AKTA), filtration equipment, and analytical tools, as well as knowledge of GMP/GLP regulations, is typically required. Strong problem-solving, attention to detail, and effective teamwork and communication skills help you navigate complex experiments and collaborate with cross-functional teams. These skills ensure efficient process optimization, compliance with regulatory standards, and successful development of biopharmaceutical products.

What is the difference between Associate Downstream Process Development Scientist vs Associate Upstream Process Development Scientist?

AspectAssociate Downstream Process Development ScientistAssociate Upstream Process Development Scientist
Primary FocusPurification and recovery of bioproductsCell culture and fermentation processes
Required SkillsProtein purification, chromatography, filtrationCell culture, bioreactor operation, media preparation
Work EnvironmentLaboratories, manufacturing facilitiesLaboratories, bioreactor labs
Common CertificationsBiotech or bioprocessing certificationsBiotech or bioprocessing certifications

Both roles are essential in biopharmaceutical development, focusing on different stages of the production process. The Associate Downstream Process Development Scientist specializes in purification techniques, while the Associate Upstream Process Development Scientist concentrates on cell growth and fermentation. Understanding these distinctions helps candidates target their skills and career paths effectively.

What are some typical challenges faced by an Associate Downstream Process Development Scientist, and how can they be addressed?

Associate Downstream Process Development Scientists often encounter challenges such as optimizing purification processes, troubleshooting equipment performance, and ensuring batch-to-batch consistency. These challenges can be addressed by maintaining meticulous documentation, collaborating closely with upstream and analytical teams, and staying current with best practices in chromatography and filtration. Proactively seeking feedback from experienced colleagues and participating in cross-functional meetings can also help in identifying solutions and improving process efficiency.
What are the most commonly searched types of Downstream Process Development Scientist jobs in Missouri? The most popular types of Downstream Process Development Scientist jobs in Missouri are:
What cities in Missouri are hiring for Associate Downstream Process Development Scientist jobs? Cities in Missouri with the most Associate Downstream Process Development Scientist job openings:

$89K - $134K/yr

Full-time

Medical, Retirement, PTO

Posted 22 days ago


Job description

Work Location: St. Louis, Missouri
Shift: No
Department: LS-PS-ATA PDS Region 1
Hiring Manager: Ben Roman


This information is for internals only. Please do not share outside of the organization.


Your role:

MilliporeSigma is looking for a Process Development Scientist to join the technical branch of the commercial organization in the Midwest, working remotely from Indianapolis, Chicago, St. Louis or Minneapolis, and supporting process development and manufacturing sciences activities. The development scientist is part of a worldwide team of engineers and scientists reporting into the technical support group for MilliporeSigma's Process Solutions business.

  • Lead development studies for purification of therapeutic proteins using MilliporeSigma technologies (sterile filtration, depth filtration, tangential flow filtration, viral reduction filtration, chromatography)
  • Involve in selection/sizing, process optimization, and tech transfer for purification of new pharmaceuticals, focused on Phase I-III development
  • Provide customer consultations via email, telephone, or video
  • Collaborate with customer process development groups in the Central United States
  • Partner with local MilliporeSigma account managers to deliver technical expertise to customers
  • Support clinical and commercial scale implementations using sound engineering principles, including identifying CQAs and maintaining critical control parameters
  • Document customer interfacing activities in electronic systems; propose new technical ideas for the broader group and contribute to cross-functional strategy execution
  • This position will include travel of up to 30% within North America region

Physical attributes:

  • Lifting of up to 50 pounds

Who you are:

Minimum Qualifications:

  • Bachelor's degree in Chemical Engineering, Biotechnology, Pharmaceutical Sciences, or other Life Science discipline
  • 3+ years of experience within pharmaceutical development, technology implementation, or protein or viral particle purification

-OR-

  • Master's degree in Chemical Engineering, Biotechnology, Pharmaceutical Sciences, or other Life Science discipline
  • 2+ years of experience within pharmaceutical development, technology implementation, or protein or viral particle purification

-OR-

  • PhD in Chemical Engineering, Biotechnology, Pharmaceutical Sciences, or other Life Sciences discipline
  • 1+ years of experience within pharmaceutical development, technology implementation, or protein or viral particle purification

Preferred Qualifications:

  • An in-depth knowledge and understanding of bioprocess unit operations
  • Ability to derive relevant conclusions, based on the experimental results, and effectively communicate this to our customers
  • Excellent hands on laboratory skills, working knowledge of Microsoft Excel or other data analysis software
  • Sound understanding of downstream and/or upstream biomanufacturing process requirements, best practices, and industry standards
  • Comfort with making recommendations for future course of action based on experimental results
  • Ability to relay relevant results to sales, field marketing, etc.
  • Ability to identify scientific leadership opportunities and execute through lunch & learns, publications, presentations, etc. with a focus on customer collaboration
  • Ability to cope with change, adjust test plans quickly, and comfortably handle risk and uncertainty
  • Ability to build effective relationships; both internally and externally
  • Ability to produce quality written experimental reports and other appropriate documentation
  • Highly motivated, self-directed, and able to work independently in a field-based position
  • Demonstrated ability to communicate clearly, concisely and effectively to diverse audiences through both written and oral communications

Pay Range for this position: $89,800-$134,700.

The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information clickhere.

RSREMD


The Company is an Equal Employment Opportunity employer. No employee or applicant for employment will be discriminated against on the basis of race, color, religion, age, sex, sexual orientation, national origin, ancestry, disability, military or veteran status, genetic information, gender identity, transgender status, marital status, or any other classification protected by applicable federal, state, or local law. This policy of Equal Employment Opportunity applies to all policies and programs relating to recruitment and hiring, promotion, compensation, benefits, discipline, termination, and all other terms and conditions of employment. Any applicant or employee who believes they have been discriminated against by the Company or anyone acting on behalf of the Company must report any concerns to their Human Resources Business Partner, Legal, or Compliance immediately. The Company will not retaliate against any individual because they made a good faith report of discrimination.

Employment Type: FULL_TIME