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Associate Downstream Process Development Scientist Jobs in Illinois

Senior R&D Scientist

Dakota, IL · On-site

$93K - $119K/yr

The Sr. R&D Scientist will be an expert in the formulation of milk/dairy-based beverage products ... and processes for plant trials and production. • Work cross-functionally with Operations ...

Summary Title: R&D Process Development Engineer Location: Chicago, IL  Compensation: Competitive ... scientists and engineers building Numat's current and next-generation products. The work is ...

Summary Title: R&D Process Development Engineer Location: Chicago, IL Compensation: Competitive ... scientists and engineers building Numat's current and next-generation products. The work is ...

Summary Title: R&D Process Development Engineer Location: Chicago, IL Compensation: Competitive ... scientists and engineers building Numat's current and next-generation products. The work is ...

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Associate Downstream Process Development Scientist information

What is an Associate Downstream Process Development Scientist?

An Associate Downstream Process Development Scientist is a professional who works in the biotechnology or pharmaceutical industry, focusing on developing and optimizing processes that purify biological products, such as proteins or antibodies, after they have been produced by cells. Their work is crucial for ensuring the final product meets quality and safety standards before it is used in research or clinical applications. They typically perform laboratory experiments, analyze data, and collaborate with other scientists and engineers to improve yield and efficiency. This role is often entry-level or early-career, providing hands-on experience in process development and technical troubleshooting.

What are the key skills and qualifications needed to thrive as an Associate Downstream Process Development Scientist, and why are they important?

To excel as an Associate Downstream Process Development Scientist, you need a solid understanding of biochemistry, chemical engineering, and downstream purification techniques, often supported by a bachelor's or master's degree in a life science or engineering discipline. Familiarity with chromatographic systems (such as AKTA), filtration equipment, and analytical tools, as well as knowledge of GMP/GLP regulations, is typically required. Strong problem-solving, attention to detail, and effective teamwork and communication skills help you navigate complex experiments and collaborate with cross-functional teams. These skills ensure efficient process optimization, compliance with regulatory standards, and successful development of biopharmaceutical products.

What is the difference between Associate Downstream Process Development Scientist vs Associate Upstream Process Development Scientist?

AspectAssociate Downstream Process Development ScientistAssociate Upstream Process Development Scientist
Primary FocusPurification and recovery of bioproductsCell culture and fermentation processes
Required SkillsProtein purification, chromatography, filtrationCell culture, bioreactor operation, media preparation
Work EnvironmentLaboratories, manufacturing facilitiesLaboratories, bioreactor labs
Common CertificationsBiotech or bioprocessing certificationsBiotech or bioprocessing certifications

Both roles are essential in biopharmaceutical development, focusing on different stages of the production process. The Associate Downstream Process Development Scientist specializes in purification techniques, while the Associate Upstream Process Development Scientist concentrates on cell growth and fermentation. Understanding these distinctions helps candidates target their skills and career paths effectively.

What are some typical challenges faced by an Associate Downstream Process Development Scientist, and how can they be addressed?

Associate Downstream Process Development Scientists often encounter challenges such as optimizing purification processes, troubleshooting equipment performance, and ensuring batch-to-batch consistency. These challenges can be addressed by maintaining meticulous documentation, collaborating closely with upstream and analytical teams, and staying current with best practices in chromatography and filtration. Proactively seeking feedback from experienced colleagues and participating in cross-functional meetings can also help in identifying solutions and improving process efficiency.
What are the most commonly searched types of Downstream Process Development Scientist jobs in Illinois? The most popular types of Downstream Process Development Scientist jobs in Illinois are:
What cities in Illinois are hiring for Associate Downstream Process Development Scientist jobs? Cities in Illinois with the most Associate Downstream Process Development Scientist job openings:
Senior Principal Research Scientist Engineering

Senior Principal Research Scientist Engineering

AbbVie

North Chicago, IL • On-site

$160K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 5 days ago


AbbVie rating

8.7

Company rating: 8.7 out of 10

Based on 100 frontline employees who took The Breakroom Quiz

12th of 74 rated pharmaceutical


Job description

Company Description
About AbbVie
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.
R&D Process Engineering Organization, a part of AbbVie's Development Sciences organization, is responsible for designing and developing scalable processes to make drug substances and drug products, including synthetics molecules, antibody drug conjugates (ADCs) and genetic medicines, throughout pre-clinical and clinical development stages. Process Engineering also partners with Biologics CMC (Chemistry, Manufacturing, and Controls) Development and Aesthetics R&D functions to provide active engineering support to enable robust process scale-up and manufacturing of biologics drug substances and drug products including toxins and cosmetic active ingredients (CAIs). It drives the development of innovative engineering technologies and creates valuable intellectual property through the composition of matter and chemical/bio-chemical processes resulting in cost-effective commercial manufacturing processes for quality products. Process Engineering organization also supports the scale-up in the pilot plants and supply chain development for pipeline molecules and supports the justification of CMC regulatory content.
Job Description
Role Overview
The successful Process Engineering candidate will play a key technical team leader role in the R&D Process Engineering function. In addition to a strong background in fundamentals of chemical engineering, the ideal candidate will have demonstrated experience in the biologics, peptides, ADC development and genetic medicines as a strong technical team leader. The candidate must have demonstrated initiative in building and sustaining cross-functional collaborations. In addition to leading the technical team, the successful candidate is also expected to lead the identification and development of novel approaches and technologies to enhance process development efficiency and commercialization of novel modalities. The candidate must exhibit a collaborative behavior in proactively identifying process challenges on a wide range of pipeline and innovation projects, take a leadership role in a cross-functional team to deliver specific project needs, and take on a scientific leadership role in developing and implementing solutions.
Key Responsibilities:
  • Develop robust manufacturing processes, supporting assets including novel modalities through all phases of clinical development.
  • Lead project teams towards process development and characterization of new synthetic and large molecule assets.
  • Influence process development of toxins, cosmetic active ingredients and genetic medicines proactively.
  • Lead scale-up of laboratory processes in the pilot plant.
  • Set project strategies, define project responsibilities and timelines, and provide leadership in a matrixed team setting.
  • Address challenging problems with biochemical reactions, separations, and/or isolations using expertise in reaction kinetics, transport phenomena, and mathematical modeling.
  • Establish, communicate, and execute research plans.
  • Exhibit a collaborative nature in identifying process challenges on a wide range of projects and communicate findings and recommendations effectively by multi-disciplinary interactions with organic chemists, analytical chemists, process development engineers, pilot plant engineers, drug product development scientists, program managers, and regulatory affairs specialists.
  • Author and/or review technical documents summarizing process development efforts and contribute to regulatory filings.
  • Strengthen scientific brand of Process Engineering while providing mentorship to direct reports and process engineering colleagues.

Qualifications
  • BS, MS, or PhD in Chemical/Bio Engineering or a related field and 18+ (BS), 16+ (MS), or 10+ (PhD) years of relevant biopharmaceuticals industrial experience.
  • Ph.D. candidates with pertinent research exposure are also encouraged to apply.
  • Job level will be commensurate with academic and/or industrial work experience.
  • Candidates are expected to have a strong foundations in chemical engineering and the proven ability to demonstrate their skills in this field.
  • The candidate is expected to demonstrate the ability to solve challenging technical problems and champion next generation of innovative technologies to achieve project goals around novel modalities.
  • The candidate is required to be a strong team player and demonstrate scientific leadership, possessing effective oral and written communication skills for facilitating co-creation and leading cross-functional process development teams.

Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
  • The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this postingbased on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more orless than the posted range. This range may be modified in the future.
  • We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
  • This job is eligible to participate in our short-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission,incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paidand may be modified at the Company's sole and absolute discretion, consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html
US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:
https://www.abbvie.com/join-us/reasonable-accommodations.html

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About AbbVie

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AbbVie's mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women's health, and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube, and LinkedIn.

Industry

Scientific research and development services

Company size

10,000+ Employees

Headquarters location

North Chicago, IL, US

Year founded

2013