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Associate Director, Pharmacometrics

Associate Director/Director, Pharmacometrician Step into a role where science meets strategy and ... You will design, analyze, and interpret clinical pharmacology studies, provide strategic guidance ...

Iambic Therapeutics, Inc

$164K - $245K/yr

JOB SUMMARY The Associate Director/Director will be responsible for designing and executing clinical pharmacology strategy for oncology small-molecule programs, including PK/PD study design, dose ...

Merck & Co.

$156K - $247K/yr

The department of Pharmacokinetics, Dynamics, Metabolism & Bioanalytics (PDMB) is seeking a curious and collaborative Scientific Associate Director for our growing Translational PK/PD organization.

Merck & Co.

$156K - $247K/yr

The department of Pharmacokinetics, Dynamics, Metabolism & Bioanalytics (PDMB) is seeking a curious and collaborative Scientific Associate Director for our growing Translational PK/PD organization.

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How much do associate director pharmacovigilance jobs pay per year?

As of Sep 3, 2026, the average yearly pay for associate director pharmacovigilance in the United States is $164,797.00, according to ZipRecruiter salary data. Most workers in this role earn between $121,500.00 and $200,000.00 per year, depending on experience, location, and employer.

What does an associate director pharmacovigilance do?

An Associate Director of Pharmacovigilance is responsible for overseeing drug safety activities, ensuring compliance with global pharmacovigilance regulations, and managing safety data collection, analysis, and reporting. They lead teams that monitor and evaluate adverse events related to pharmaceutical products, work closely with regulatory authorities, and help develop risk management strategies. Their work is crucial in maintaining drug safety and ensuring patient well-being throughout the product lifecycle.

How does an associate director pharmacovigilance typically collaborate with cross-functional teams within a pharmaceutical company?

As an Associate Director of Pharmacovigilance, you will regularly collaborate with teams across clinical development, regulatory affairs, medical affairs, and quality assurance. Your role often involves leading safety review meetings, coordinating safety data exchange agreements, and ensuring timely communication of safety information both internally and to regulatory authorities. This cross-functional collaboration is essential for maintaining compliance with global safety regulations and for supporting the safe development and commercialization of pharmaceutical products. Building strong relationships and clear lines of communication with these teams will be crucial to your success and impact in the role.

What are the key skills and qualifications needed to thrive as an associate director pharmacovigilance, and why are they important?

To thrive as an Associate Director Pharmacovigilance, you need in-depth knowledge of drug safety regulations, clinical development, and risk management, typically supported by an advanced degree in life sciences or pharmacy. Familiarity with pharmacovigilance databases (such as Argus or ARISg), regulatory reporting systems, and certifications like RAPS or DIA are commonly required. Exceptional leadership, analytical thinking, and strong communication skills set standout candidates apart. These abilities ensure effective oversight of drug safety operations, regulatory compliance, and timely risk mitigation for patient safety.
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Associate Director Pharmacovigilance jobs near you
Infographic showing various Associate Director Pharmacovigilance job openings in the United States as of August 2026, with employment types broken down into 100% Full Time. Highlights an 33% Hybrid, and 67% Remote job distribution, with an average salary of $164,797 per year, or $79.2 per hour.

Associate Director, Quantitative Systems Pharmacology

Alnylam Pharmaceuticals

Cambridge, MA • On-site

$175K - $237K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 10 days ago

Job description

Associate Director, Quantitative Systems Pharmacology
Overview
The Associate Director, Quantitative Systems Pharmacology (QSP) will support a rapidly expanding clinical portfolio of promising RNAi therapeutics. The candidate in this position should be well versed in systems pharmacology, clinical pharmacology, PK and PD with ability to critically evaluate and interpret data and conduct data analysis. In this role, the candidate is expected to show a high degree of scientific curiosity and critical thinking ability with good oral and written communication skills, ability to work independently with minimal supervision in a highly matrixed environment. The Associate Director, QSP will champion the application of QSP modeling and simulation approaches to answer key drug development questions across the portfolio spanning all stages of drug development.
Key Responsibilities
  • With minimal supervision, strategize, formulate and execute QSP modeling and simulation approaches for insights into dose selection, trial design, mechanistic understanding of the interaction between disease, biomarker and treatment response, predicting clinical outcomes etc.
  • Closely partner with clinical pharmacologist, pharmacometricians, research, clinical, non clinical modelers and other relevant R&D functions. Work closely with research and clinical functions to identify and interpret preclinical and clinical data to guide in data generation relevant for building and refining QSP models.
  • Build and utilize QSP models of biological or pathophysiological process to understand the disease pathways and effect of treatment intervention. Independently analyzes, interprets, and reports QSP modeling results for internal decision making.
  • Stay informed about advancement in QSP modeling methodologies. Be a technical leader within the group and mentor team members.
  • Establish and advance visibility and impact of QSP modeling internally and externally through publications in peer reviewed journals and presentations at scientific meetings.
  • Explore synergy between QSP and other modeling approaches to inform drug development decisions.

Qualifications
  • Candidates with a Ph.D (or equivalent) degree in applied mathematics, biomedical engineering, systems biology/pharmacology or related discipline.
  • At least 5 years of experience in pharmaceutical industry, consulting, or regulatory agency.
  • Track record of application of QSP modeling to impact drug development decisions.
  • Good understanding of systems biology, physiology, pharmacokinetics and pharmacodynamic principles. Strong foundation of theory, principles and statistical aspects of modeling and simulation including differential equation based modeling and parameter estimation/optimization approaches.
  • Extensive hands on experience with common QSP modeling platforms such as R, MATLAB, Simbiology etc.
  • Experience in translating and summarizing QSP modeling outcomes into information understood by project teams.
  • Open minded, receptive to input and a strong team player.
  • Self-driven, able to multi-task and manage time-sensitive deliverables.
  • Strong interpersonal skills with ability to collaborate and work in a matrix environment.
  • Strong written and oral presentation skills.

#LI-AB1 #LI-Hybrid
U.S. Pay Range
$175,800.00 - $237,800.00
The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).
Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together.
Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers
About Alnylam
We are the leader in RNAi therapeutics - a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another.
At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

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