ZipRecruiter

Log In

1

Analytical Science Jobs in California (NOW HIRING)

Prolific Machines

Analytical Scientist I

Emeryville, CA · On-site

$120K - $140K/yr

The Analytical Science team is looking for a talented scientist to collaboratively work with our R&D and Bioprocess teams to quantify and characterize broad classes of therapeutic proteins. A ...

Prolific Machines

Analytical Scientist I

Emeryville, CA · On-site

$120K - $140K/yr

The Analytical Science team is looking for a talented scientist to collaboratively work with our R&D and Bioprocess teams to quantify and characterize broad classes of therapeutic proteins. A ...

Prolific Machines

Analytical Scientist I

Emeryville, CA · On-site

$120K - $140K/yr

The Analytical Science team is looking for a talented scientist to collaboratively work with our R&D and Bioprocess teams to quantify and characterize broad classes of therapeutic proteins. A ...

5AM Ventures

Analytical Scientist

Emeryville, CA

$140K - $170K/yr

PhD in Analytical Chemistry, Pharmaceutical Sciences, Biochemistry, or related field * 8-15+ years of relevant experience in biotech, pharma, or CRO environments * Demonstrated expertise in ...

Pivotal

Analytical Scientist, Ph.D.

San Diego, CA · On-site

Salary Range $110,000 - $140,000 per year Analytical Scientist, Ph.D. Location: San Diego, CA Job Type: Full-Time, Onsite About Us We are an innovative, stealth-mode biotech focused on developing ...

5AM Ventures

Analytical Scientist

Emeryville, CA · On-site

$140K - $170K/yr

PhD in Analytical Chemistry, Pharmaceutical Sciences, Biochemistry, or related field * 8-15+ years of relevant experience in biotech, pharma, or CRO environments * Demonstrated expertise in ...

5AM Ventures

Analytical Scientist

Emeryville, CA

$140K - $170K/yr

PhD in Analytical Chemistry, Pharmaceutical Sciences, Biochemistry, or related field * 8-15+ years of relevant experience in biotech, pharma, or CRO environments * Demonstrated expertise in ...

Eurofins

Analytical Chemistry Scientist

Oceanside, CA · On-site

$52K - $60K/yr

Support other areas of the analytical development group as necessary to meet program requirements Qualifications Bachelor's degree in Biochemistry or related Science discipline with at least 2+ years ...

next page

Showing results 1-20

All JobsAnalytical Science JobsAnalytical Science Jobs in California

Analytical Science information

See California salary details

$29.1K

$99.4K

$191K

How much do analytical science jobs pay per year?

As of Jul 27, 2026, the average yearly pay for analytical science in California is $99,355.00, according to ZipRecruiter salary data. Most workers in this role earn between $66,600.00 and $123,400.00 per year, depending on experience, location, and employer.

What are the typical day-to-day tasks for someone in an Analytical Science role?

Professionals in Analytical Science often spend their days designing and conducting experiments, preparing and analyzing samples using advanced instrumentation such as HPLC, GC, or mass spectrometry, and interpreting data to support research or product development. Collaboration is common, as analytical scientists frequently work alongside chemists, biologists, and quality assurance teams to ensure accurate results and compliance with regulatory standards. Regular documentation of findings and participation in team meetings to discuss results and troubleshoot challenges are also key aspects of the role.

What is the difference between Analytical Science vs Laboratory Technician?

AspectAnalytical ScienceLaboratory Technician
Required CredentialsBachelor's or higher in Chemistry, Biochemistry, or related fields; certifications like ASQ or ACS often preferredAssociate's degree or diploma in laboratory technology or related field
Work EnvironmentResearch labs, pharmaceutical companies, quality control labsClinical, industrial, or research laboratories
Employer & Industry UsagePharmaceutical, biotech, chemical manufacturing, research institutionsHospitals, manufacturing plants, research facilities

Analytical Science involves advanced testing, method development, and data analysis, often requiring higher education and specialized certifications. Laboratory Technicians perform routine tests and sample preparations, typically with less formal education. Both roles are essential in laboratory settings but differ in complexity and responsibilities.

What is analytical science?

Analytical science is a branch of science focused on the identification, quantification, and understanding of the chemical composition and structure of substances. It involves the use of advanced instruments and methods to analyze materials and solve complex problems in areas such as pharmaceuticals, environmental monitoring, food safety, and forensics. Analytical scientists develop and apply techniques like chromatography, spectroscopy, and mass spectrometry to provide valuable data for research, quality control, and regulatory compliance.

What are the key skills and qualifications needed to thrive in Analytical Science, and why are they important?

To thrive in Analytical Science, you need a solid background in chemistry, laboratory techniques, and data analysis, often supported by a degree in chemistry or a related field. Familiarity with analytical instruments like HPLC, GC-MS, and laboratory information management systems (LIMS), as well as relevant certifications, is typically required. Strong problem-solving abilities, attention to detail, and effective communication skills help professionals excel in interpreting data and collaborating with multidisciplinary teams. These skills and qualifications are crucial for ensuring accurate results, maintaining scientific rigor, and supporting innovation in research and quality control.
What are the most commonly searched types of Analytical Science jobs in California? The most popular types of Analytical Science jobs in California are:
What are popular job titles related to Analytical Science jobs in California? For Analytical Science jobs in California, the most frequently searched job titles are:
What job categories do people searching Analytical Science jobs in California look for? The top searched job categories for Analytical Science jobs in California are:
Analytical Science jobs near you
Infographic showing various Analytical Science job openings in California as of July 2026, with employment types broken down into 1% Internship, 89% Full Time, 7% Part Time, 1% Temporary, and 2% Contract. Highlights an 86% Physical, 4% Hybrid, and 10% Remote job distribution, with an average salary of $99,355 per year, or $47.8 per hour.
Analytical Scientist I

Analytical Scientist I

Prolific Machines

Emeryville, CA • On-site

$120K - $140K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 26 days ago

Job description

Prolific Machines is ushering in a new era of biotechnology with light. Our mission is to make next-generation therapies broadly available to patients. Our first-of-its-kind Photomolecular Platform uses light to precisely guide how cells produce complex biologics, enabling higher titers, improved quality, and faster development timelines. By helping partners overcome today's manufacturing bottlenecks, we're accelerating the delivery of life-changing medicines. Prolific is supported by leading investors, including Bill Gates's Breakthrough Energy Ventures, Mayfield, and SOSV.
Help us create a brighter tomorrow with biology. We're looking for mission-driven, talented, and kind people to join our team.
The Analytical Science team is looking for a talented scientist to collaboratively work with our R&D and Bioprocess teams to quantify and characterize broad classes of therapeutic proteins. A successful candidate will bring an outcome-oriented skillset to recombinant protein quantification and characterization. You will work collaboratively with our teams to produce and purify diverse proteins from cell culture processes and be comfortable conducting a wide range of protein quality assessments. This role will be based on-site in Emeryville, CA.
Key Responsibilities
  • Develop, optimize, and validate assays for protein quality and purity for broad classes of recombinant therapeutic proteins.
  • Plan and execute experimentation to understand protein quality through cell line, upstream and downstream process development.
  • Execute, summarize, and interpret routine and complex therapeutic protein characterizations.
  • Qualify and validate assays upholding highly rigorous standards for execution and documentation.
  • Routinely operate, maintain, and troubleshoot analytical instrumentation (HPLCs, FPLCs, mass spectrometers).
  • Author, review, and implement methods, protocols, validations, and standard operating procedures.
  • Ensure processes are followed in accordance with these standards.

Qualifications & Skills
  • Hold a PhD in Analytical Chemistry, Molecular Biology, Biochemistry, Pharmaceutical Sciences, with 1+ years of biologics industry experience. Candidates without a PhD but with similar industry experience are encouraged to apply.
  • Have illustrated experience in therapeutic protein characterization approaches (eg. HPLC, SDS, CE, cIEF, LC-MS).
  • Have illustrated the ability to develop, execute, and interpret intact mass, sequence confirmation, and PTM analysis (e.g., glycosylation, disulfide mapping, peptide mapping) through mass spectrometry.
  • Have illustrated the ability to develop, execute, and interpret aggregation and charge variant characterizations for biologics.
  • Have experience in the development and execution of GLP-compliant methods characterizing protein quality attributes across a wide range of therapeutic classes.
  • Have hands-on experience operating LC-MS. Experience with Agilent QTOF instrumentation applied to assay protein quality is a plus, including familiarity with proteomic software.
  • Are highly motivated to deliver successful outcomes for internal and external clients.
  • Are excited to work with internal and external clients to deliver project excellence.
  • Have strong communication skills and are comfortable teaching and sharing knowledge at multiple levels of technical detail.

$120,000 - $140,000 a year
This role is salaried, exempt, and paid semi-monthly. Starting salary will be dependent upon specific experience, knowledge, and skillset. The range for the Scientist I level will typically fall between $120k-$140k.
Benefits: Generous equity package in an early stage company, retirement plan with company contribution, flexible PTO with healthy time off minimums, company-covered medical, dental, and vision insurance, life and disability insurance, career coaching, mental health support, free team lunches everyday, great snacks, and companywide social events!
Diversity: Prolific Machines values diverse perspectives, backgrounds, experiences, and ideas. We are committed to building an inclusive workplace where all employees can bring their authentic selves to work and have equal opportunities to succeed. Prolific Machines is proud to be an equal opportunity employer and does not discriminate on the basis of race, color, religion, creed, sex, gender identity or expression, sexual orientation, national origin, ancestry, age, disability, medical condition, genetic information, marital status, military or veteran status, or any other characteristic protected by applicable law.

Apply