ABOUT THE ROLE
The Sr. Scientist LNP Formulation & Process Development will contribute to the development and optimization of nChroma's Lipid Nanoparticle (LNP) formulations and collaborate with both internal research teams and external CROs/CDMOs to support multiple programs spanning early research and development.
RESPONSIBILITIES
- Leverage both internal team and external CROs to optimize and produce high quality LNPs to support efforts spanning early research and development.
- Provide SME support for external production with our CDMO partners.
- Lead from the bench and contribute to a high-performing Formulation & PD team, including initiating excellent laboratory and documentation practices, and providing mentorship and development opportunities for junior team members.
- Contribute as CMC representative for GMP production support & regulatory filings as needed. Collaborate with key stakeholders from research, drug substance, analytical development, pharmacology and other internal functions to support program, department, and corporate goals.
SKILLS & COMPETENCIES:
- Hands on experience with LNP formulation including optimization, conjugation, scale-up.
- Direct managerial experience.
- Excellent analytical, problem solving and critical thinking skills, including an ability to combine attention to detail with a big picture perspective.
- Strong oral and written communication skills with experience presenting scientific research.
- Ability to thrive in a fast-paced, innovative, and, at times, uncertain or changing environment while remaining flexible, proactive, and resourceful.
- Adept at prioritizing and managing multiple tasks simultaneously, integrating cross-functional issues, and balancing competing priorities effectively.
- Collaborative and team-oriented mindset with a desire to positively impact culture.
QUALIFICATIONS:
- 4-5 years in the biopharmaceutical industry with a proven track record with nucleic acids delivery, LNP formulation and scale up, including tech transfer to GMP suites.
- Advanced degree in Chemistry, Biophysics, Biochemistry, Bioengineering, or related life sciences with strong scientific background.
- Preferred in-depth experience with analytical assays for LNP characterization.
- Experience providing guidance and mentorship to junior scientists.
- Experience supporting development programs, including communicating between CMC and Program Teams.
The salary range for this role is $145K - $175K