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Job Summary: The Manager, Laboratory Research Operations provides comprehensive administrative and scientific support for the Dean lab, which aims to define and target pathways that increase cardiometabolic disease and diabetes using animal models and human samples. This role manages and oversees the day-to-day administration and operations of the laboratory, ensuring compliance with all regulatory requirements and optimizing research productivity.
Key Responsibilities:
Administrative and Operational Management: The Manager, Laboratory Research Operations oversees daily laboratory operations, including administrative, fiscal, and human resources activities. This includes managing laboratory inventory, procuring supplies and equipment, and tracking expenditures. The manager is responsible for developing and recommending annual operating budgets, overseeing budget implementation, and financial reporting. Ensuring compliance with Federal and University regulations, such as HIPAA, IRB, IBC, IACUC, and EHS, is a critical part of the role, along with coordinating periodic maintenance and testing of laboratory equipment.
Scientific and Research Support: In terms of scientific and research support, the manager designs and executes complex scientific experiments using advanced molecular and cellular techniques, analyzes and interprets research data, and develops and implements new research methodologies. They monitor laboratory animal colonies, including mouse genotyping and colony maintenance, perform animal surgery and postoperative care, and assist in the planning, design, development, and troubleshooting of animal experimental protocols and molecular techniques. Additionally, they perform critical analyses of literature relevant to ongoing research and assist in the preparation of research papers, manuscripts, project reports, and funding proposals.
Team Leadership and Collaboration: The manager also leads, plans, and manages the hiring, training, and supervision of research staff, including postdoctoral researchers, graduate and undergraduate students. They collaborate with faculty and staff to establish standard operating procedures and support training initiatives, coordinate laboratory meetings, and facilitate discussions on current research and laboratory agenda items. Acting as the primary contact for regulatory bodies and other principal investigators regarding technical advice, protocol assistance, and shared resources is another key responsibility. They also help other lab members with studies, data processing, and analysis.
Compliance and Safety: Ensuring laboratory safety and compliance with all regulatory requirements is paramount. The manager conducts periodic laboratory inspections and initiates training sessions as needed. They represent the organization in interactions with funding agencies and in the development of financial resources and programs.
Additional Duties: Additional duties include ensuring the laboratory is prepared for experiments, including inventory control, ordering supplies, and lab and equipment maintenance. They
contribute to team discipline and performance by explaining policies, standards, and processes to others.
Qualifications:
Prior experience with animal studies is required.
Preferred experience with mouse genotyping, colony maintenance, and molecular biology techniques (e.g., western blot, real-time PCR).
Preferred experience with mouse pancreatic islet isolation, ELISAs, and fluorescent microscopy and image analysis. Is okay
Highly motivated and detail-oriented individual.

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