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The Xu Lab at the Center for Retrovirus Research at The Ohio State University is seeking a highly motivated Research Technician to support cutting-edge research in vaccine design and antibody therapeutic discovery. This is a long-term position (expected commitment of >3 years) for a dedicated and reliable laboratory professional. This position is subject to a 6-month probationary period, during which performance, technical skills, and laboratory fit will be evaluated prior to continuation of long-term appointment. The primary responsibility of this role is to support the laboratory's protein production pipeline, with a strong focus on molecular cloning and recombinant protein purification. The successful candidate will play a key role in generating high-quality protein reagents thatsupport our research, withopportunity to contribute to high-impact publications and translational research programs.

Key Responsibilities:

• Design, perform, and optimize molecular cloning for recombinant protein and antibody expression constructs.

• Conduct protein expression and purification in bacterial, insect, and mammalian systems.

• Operate and maintain chromatography systems (e.g., AKTA/FPLC) for multi-step purification workflows.

• Optimize expression constructs and purification conditions to improve protein yield, purity, and stability.

• Maintain detailed, accurate, and reproducible experimental records.

• Manage laboratory reagents, inventory, and general laboratory organization.

• Provide consistent technical support to postdoctoral fellows and graduate students.

Working Conditions:

• Bachelor's degree in Biochemistry, or a related field.

• Hands-on experience in molecular cloning and recombinant protein expression/purification.

• Strong understanding of molecular biology and protein biochemistry principles.

• Excellent attention to detail and strong commitment to reproducibility and high-quality experimental work.

• Ability to work independently and as a reliable member of a collaborative team.

• Strong commitment to along-term position (3 years)with stability and continuity in laboratory support work.

• Excellent organizational skills, attention to detail, and strong teamwork and communication abilities.

• Ability to manage multiple ongoing tasks.

• Proven track record of successful laboratory work in protein expression, purification,andrelated molecular biology/biochemistry techniques.

Target Salary Range: $15.86 - $20.74per hour; commensurate with experience, internal equity, the unit's available budget, and the candidate's qualifications.