Vaxcyte
Vaxcyte

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    Infographic showing various Research job openings at Vaxcyte in the United States as of August 2026, with employment types broken down into 97% Full Time, and 3% Part Time. Highlights an 76% Physical, 7% Hybrid, and 17% Remote job distribution.

    Associate Scientist II (Contract), Research

    Vaxcyte

    San Carlos, CA • On-site

    $51 - $56/hr

    Full-time

    This job post has expired 1 day ago. Applications are no longer accepted.


    Job description

    Summary:

    Vaxcyte's Research team uses a broad palette of chromatographic tools to purify diverse vaccine antigens. Applicants must have practical, hands-on experience with multiple chromatographic modalities (not limited to monoclonal antibody/Protein A workflows). Experience should include selection, screening, development, scale-up and characterization of various chromatography techniques. 

    Essential Functions:
    • Execute the following AKTA FPLC chromatography techniques:
      • Immobilized metal affinity chromatography (IMAC)
      • Ion-exchange chromatography (IEX)
      • Hydrophobic interaction chromatography (HIC)
      • Size-exclusion chromatography (SEC)
      • Hydroxyapatite (CHT / HA)
    • Designing chromatography trains to reduce host cell protein, endotoxin and aggregates using complementary modalities.
    • Demonstrated DoE experience for multimodal optimization is a plus.
    • Membrane chromatography for high-throughput contaminant removal or virus/VLP processing and as a scale-friendly polishing/scavenging step.
    • Keep accurate and current records of development experiments and/or project related activities in an electronic laboratory notebook.
    • Present data from experiments to the team and contribute to technical discussions.
    • Work within a team environment and provides support as necessary to further the team's initiatives.
    Requirements: 
    • BS in Biochemistry, Molecular Biology or a relevant science considered, with minimum of 2 years of relevant industry experience or MS with minimum of 1 year of relevant industry experience.
    • Experience with diverse protein targets, bacterial and eukaryotic recombinant proteins, small/large subunit vaccine antigens, fusion proteins, multimeric complexes, glycoproteins, and VLPs.
    • The role requires demonstrated success with alternative capture/polishing methods and orthogonal cleaning strategies appropriate for potential vaccine antigens.
    • Preferred experience with Cell-free protein synthesis system.
    • Familiarity with automation or high throughput workflows such as (96-well plates) and UNICORN/AKTA software DoE integrations.
    • Experience in process development.
    • Strong interpersonal skills to collaborate well within the team and excellent written and verbal communication skills.
    Reports to: Scientist II, Research 
     
    Location: San Carlos, CA
     
    Work Arrangement: Onsite 
     
    Expected Contract Length: 12months 
     
    Hourly Range: $51/hr. - $56/hr.

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    About Vaxcyte

    Sourced by ZipRecruiter

    Industry

    Biotechnology research and development

    Company size

    51 - 200 Employees

    Headquarters location

    San Carlos, CA, US

    Year founded

    2013