60 Exelixis Operations Jobs Hiring Near You

Job Summary:
Exelixis is a company focused on advancing cancer care, and they are seeking a Senior Staff Engineer – Client Technology. This role is responsible for the ownership, security, and governance of IT platforms and products, utilizing advanced problem-solving techniques to manage complex technical issues.
Responsibilities:
• Own the overarching strategy and execution for assigned IT platforms, tools, and products
• Drive alignment between technology and the business, utilizing a keen understanding of business needs and the interdependencies between products
• Utilize conceptual thinking to drive engineering decisions across platforms and solutions
• Pinpoint systemic issues and devise robust, scalable solutions
• Understand and manage interdependencies across systems and environments
• Thoroughly test fixes and enhancements across multiple environments
• Develop and maintain secure, self-documented scripts with error handling and logging
• Collaborate cross-functionally to align platform capabilities with business needs
• Meet with customers and incorporate feedback into the product roadmap through multiple means and channels
• Influence engineering decisions by advocating for stakeholder needs and aligning technical approaches with business priorities
• Drive operational and technical excellence across one or more IT platforms or products
• Document architecture, configurations, and operational procedures
• Make decisions regarding access, permissions, and security controls across systems
• Lead incident response and root cause analysis for high-impact issues
• Contribute to compliance readiness by implementing controls and processes that support audit and regulatory requirements
• Serve as the SME for assigned capabilities, providing technical leadership and guidance
• Mentor and coach junior engineers, fostering technical growth and best practices
Qualifications:
Required:
• Associate degree and 11 years of experience; or
• Bachelor’s degree and 9 years of related experience; or
• Master’s degree and 7 years of related experience; or
• Equivalent combination of education and experience.
• Technical certification may be required
• Proven experience owning and securing complex IT platforms and tools
• Demonstrated ability to lead technical projects and mentor junior engineers
• Experience making access and security decisions across enterprise systems
• Strong scripting and automation skills with production-grade code
• Familiarity with IT security frameworks and governance models
• Experience working in Agile environments and using ticketing systems (e.g., JIRA, JSM)
• Own Apple and mobile endpoint engineering across macOS, iPadOS, and BYOD (iOS & Android), partnering with the Windows endpoint team to align with enterprise endpoint management, security, and operational objectives.
• Design, implement, and operate macOS management using Microsoft Intune (MDM / DDM where applicable), including configuration profiles, compliance policies, monitoring, reporting, and day 2 support.
• Maintain continuity in the existing Jamf managed macOS environment while contributing to the organization’s longer term evolution toward an Intune first management approach.
• Define and maintain Mac and iPad device standards, including baseline configuration, security requirements, compliance expectations, and lifecycle management aligned with enterprise best practices. While partnering with internal stakeholders on identity, access, and compliance integration for Apple and mobile platforms, including Entra registration, device compliance signaling, and Conditional Access enforcement.
• Own iPadOS device management (Entra managed) and engineer BYOD management for iOS and Android using Intune MAM/App Protection Policies, enabling secure access to corporate data with appropriate user and device boundaries.
• Drive automation and scalable application and device management across macOS, iPadOS, and mobile platforms, using scripting, AI, and tooling to improve reliability, reduce manual effort, and support consistent packaging, deployment, update cadence, and troubleshooting processes.
• Establish and enforce guardrails for AI assisted workflows and automation within endpoint management platforms, ensuring safe usage, auditability, and alignment with security and compliance governance.
• Review and approve AI assisted operational changes and automation for risk, access scope, auditability, and system impact; document architectures and define escalation patterns for AI workflow failure modes.
• Expert-level knowledge in multiple client technology areas and enterprise systems
• Proven ability to lead cross-functional initiatives and drive technical strategy
• Skilled in stakeholder communication, risk assessment, and change management
• Experience developing standards, governance models, and technical roadmaps
• Strong understanding of enterprise architecture and integration patterns
• Can conceptualize new and innovative ways to solve complex business problems
• Expert knowledge of product-centric and agile framework models
Company:
Exelixis works is focused on discovering, developing and commercializing therapies for the treatment of cancer and other serious diseases. Founded in 1994, the company is headquartered in Alameda, USA, with a team of 1001-5000 employees. The company is currently Late Stage.