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Plainsvc

16 jobs near Columbus, OH

Plainsvc

Battery Scientist / Ten-Nine Tech

Tulsa, OK · On-site

Employment Opportunities Ten‑Nine Technologies is a leading provider of innovative material solutions, specializing in battery additives. We are committed to pushing the boundaries of technology to ...

Plainsvc

Logistician / Firehawk Aerospace

Addison, TX · On-site

About Firehawk Aerospace Firehawk Aerospace is pioneering the development of additively manufactured rocket propulsion systems, combining advanced manufacturing techniques with innovative engineering ...

Plainsvc

Firehawk Aerospace is a leading propulsion-focused aerospace and defense company located in Addison, TX. Our innovative approach empowers us to design and manufacture cutting-edge solid and hybrid ...

Upstream Senior Scientist, Process Development / Wheeler Bio

Oklahoma City, OK • On-site

Plainsvc
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$85K - $116K/yr

Other

Posted 22 days ago

Job description

Description

As an upstream Process Development Senior Scientist, you will support the development, optimization, and scale-up of mammalian upstream bioprocesses for the manufacture of biologic drug substances. You will contribute to the design and execution of laboratory experiments, data analysis, and technical documentation.

Key Responsibilities
  • Perform laboratory experiments to support mammalian upstream (cell culture) process development.
  • Utilize Design of Experiments (DoE) for data analysis and experimental design.
  • Assist in the optimization of upstream bioprocess parameters for yield, purity, and product quality attributes, collaborating with downstream, analytical and formulation teams.
  • Support scale-up and technology transfer of processes to manufacturing or pilot facilities based on engineering principles including oxygen transfer.
  • Work cross-functionally with analytical development, MSAT, manufacturing and quality teams to drive successful technology transfer.
  • Prepare buffers, media, and other solutions according to SOPs and protocols.
  • Operate and maintain flask and bioreactor equipment.
  • Collect, analyze, and interpret experimental data; maintain accurate lab records and electronic notebooks.
  • Present findings in internal and client meetings.
  • Author technical reports and regulatory documentation.
  • Complete Root Cause Analyses as needed, implementing corrective and preventative actions as needed.
  • Mentor junior scientists and research associates in daily activities, data trending and data analysis.
  • Follow all safety, quality, and compliance requirements.
Qualifications Education
  • Bachelor’s, master’s or PhD degree in Chemical Engineering, Biochemistry, Biotechnology, Biology, or related field.
Experience
  • 5 – 12 years of hands‑on experience in a bioprocessing or biopharmaceutical development environment (academic or industrial); some education qualifications may substitute for some years of experience.
  • Experience in a CDMO environment is required.
  • Experience with suspension mammalian cell culture and stirred tank bioreactors is required.
  • Knowledge of protein purification and analytical techniques is a plus.
Skills and Knowledge
  • Understanding of cGMP, GLP, or other regulatory standards (preferred).
  • Strong analytical and problem‑solving skills.
  • Good written and verbal communication skills.
  • Ability to work both independently and in a collaborative team environment.
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