Pain Research Forum

Research Scientist, Pain Pharmacology at Vertex Pharmaceuticals San Diego

Vertex Pharmaceuticals is seeking a Pharmacology Research Scientist to join our pain pharmacology group in San Diego. We are looking for a motivated, creative, and innovative scientist with a deep understanding of ion channel physiology and pharmacology and expertise in pain research. This lab-based role involves designing mechanistic studies, developing cellular models of neuronal function, and analyzing data to guide decision-making. Preference will be given to candidates with extensive experience using cutting edge electrophysiological and imaging techniques, utilizing primary cells, including human cells. The successful candidate will demonstrate a strong desire to collaborate within a multidisciplinary drug discovery team.

Key Duties and Responsibilities:

• Design and execute pharmacology studies focused on ion channel modulation.
• Develop cellular models to study neuronal excitation, action potential propagation, and neurotransmitter release.
• Analyze, interpret and communicate pharmacological data to project teams.
• Collaborate with technology teams to integrate advanced tools into workflows.
• Ensure high standards of scientific documentation and communication.

Knowledge and Skills:

• Strong understanding of ion channel pharmacology.
• Experience with assays related to neuronal signaling and excitability.
• Experience with electrophysiological and imaging techniques, utilizing primary cells, including human cells
• Proven ability to design, execute, and interpret cellular assays.
• Strong verbal and written communication skills.
• Ability to navigate and thrive in a fast-paced, highly-matrixed work environment.
• Passion for innovative solutions that improve lives.

Education and Experience:

• PhD and 0-3 years of experience or,
• Masters degree and 3 years of experience or,
• Bachelors degree and 6 years of experience

Pay Range:

$110,900 – $166,300

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

On-Site Designated

Flex Eligibility Status:

In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at