Job Summary:
Personalis, Inc. is transforming the active management of cancer through breakthrough personalized testing. They are seeking a highly skilled Senior Network & Infrastructure Engineer to lead the architecture and maintenance of their Cisco Nexus fabric, secure their perimeter with NextGen firewalls, and support a robust environment consisting of VxRail, VMware, and petabyte-scale HPC storage.
Responsibilities:
• Architect, deploy, and optimize Cisco Nexus switches within a High-Performance Computing (HPC) environment, ensuring low latency and high throughput.
• Full lifecycle management of Cisco NextGen Firewalls (NGFW). You must be proficient in configuring security policies, routing, and VLAN segmentation.
• Lead the setup and maintenance of VPN connections (Site-to-Site and Remote Access) on Cisco platforms.
• Oversee the provisioning, monitoring, and troubleshooting of network circuits and ISP handoffs.
• Act as a subject matter expert for hybrid-cloud networking, supporting connectivity between on-premise hardware and AWS/GCP (Direct Connect/Cloud Interconnect).
• Administer and scale VMware clusters running on Dell VxRail hyperconverged infrastructure.
• Support high-performance storage environments, specifically VAST Data and Dell Isilon, ensuring data availability for intensive workloads.
• Provide tier-3 support for Linux (RHEL/Ubuntu/CentOS) and Active Directory environments.
• Manage Cisco Meraki wireless and edge networking for corporate office connectivity.
• Ensure the integrity of the environment through rigorous backup schedules and disaster recovery testing.
• Perform hardware installations (Rack & Stack), cable management, and physical troubleshooting in Colocation (Colo) and Data Center environments.
Qualifications:
Required:
• 5–8+ years of hands-on experience in network engineering and infrastructure.
• Advanced knowledge of Cisco Nexus (NX-OS) and Cisco NextGen Firewalls.
• Deep understanding of BGP, OSPF, VLANs, LACP, and VPN protocols (IPsec/SSL), WAN technologies.
• Proven experience with Dell server hardware and VxRail.
• Exposure to high-performance file systems (VAST, Isilon).
• Ability to work on-site at data centers and office/labs, including lifting up to 50 lbs and working within server racks.
Preferred:
• Experience with AWS (VPC, Transit Gateway) or GCP (Cloud Router).
• CCNP (Data Center/Security), VCP (VMware Certified Professional), or AWS Solutions Architect.
• Prior experience working in R&D, scientific, or lab environments.
• Experience with Python, Ansible, or Terraform for infrastructure-as-code.
Company:
At Personalis, we are transforming the active management of cancer through breakthrough personalized testing. Founded in 2011, the company is headquartered in Menlo Park, USA, with a team of 201-500 employees. The company is currently Growth Stage.