Nautilus Biotechnology

Job Summary:
Nautilus Biotechnology is on a mission to improve health by leveraging the potential of the proteome for drug development and personalized medicine. They are seeking a full-stack Senior Software Engineer II to contribute to their cloud-based Discovery Platform, focusing on delivering exceptional customer experiences and providing technical leadership within the engineering team.
Responsibilities:
• You will own and deliver major capabilities within our Discovery Platform, from the interactive experiences our customers use to explore and understand their results, to the backend data systems that store, process, and serve the large and complex scientific datasets that power them. You will see these capabilities through their full lifecycle: design, development, deployment, and ongoing operation.
• You will bring genuine curiosity to the science behind the data, working alongside bioinformaticians, biologists, and product teams to deeply understand what our customers are trying to learn from their results and why it matters.
• You will collaborate with teams responsible for the ETL pipelines and algorithms that transform raw instrument data into the protein quantification results our customers depend on.
• You will lead with ownership. You will drive technical design, contribute to architecture decisions, and hold a high bar for security, reliability, and scale. You will also help develop the engineers around you through thoughtful code review, mentorship, and honest technical dialogue.
• You will embrace AI as a collaborative partner across the software development lifecycle. You are skilled at prompting and critically evaluating AI-generated work, and you actively explore new ways AI can improve how we build and operate software.
Qualifications:
Required:
• You have a minimum of 5 to 7 years of relevant experience in a high-performing software engineering organization.
• A bachelor’s degree in computer science or a related field is required.
• You have a strong command of Python/FastAPI, React/TypeScript, and AWS cloud services.
• You have solid experience with relational databases and an understanding of columnar data stores.
• You are customer obsessed.
• You are focused on outcomes.
• You design software with its full lifecycle in mind.
Preferred:
• Familiarity with Parquet and query engines such as AWS Athena is a plus.
Company:
Nautilus Biotechnology is a life sciences company that develops a platform for analyzing and quantifying the human proteome. Founded in 2016, the company is headquartered in San Carlos, USA, with a team of 51-200 employees. The company is currently Growth Stage.