Kmr Search Group

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Job Opportunity Employs Nursing Professional Practice: Assesses, identifies appropriate nursing diagnoses, plans, implements and evaluates patients' care. Develops, updates and coordinates the ...

Medical Director, Cardiology-Discovery Medicine

KMR Search Group

San Francisco, CA • On-site

Full-time

Re-posted 20 days ago


Job description


Our client is looking for someone who loves the clinic as much as the science. Someone who was in the lab maybe while getting their degree (academics with bench scientist experience i.e., in the lab with recent cardiology).
Seeking a real physician scientist who has academic AND clinical development experience, someone who has owned a program. We have interviewed a lot of candidates that have no translational, genetics or science experience.
Our wish list is someone who is grounded in genetics and translational medicine (first in human).
Company is a world leader in delivering therapeutics providing significant benefit to patients who live with serious and life-threatening rare genetic diseases.
Company is engaged in the discovery, translation and development of therapies that correct severe pathologic mechanisms and produce meaningful endpoints for clinically relevant improvements in diseases. We therefore seek to discover and develop medicines that profoundly improve the quality of patients' lives.
Company's Discovery Medicine is a group of physician-scientists that support pipeline advancement and growth into clinical development.
As an early clinical development function, our group of 'scientific' clinicians link research initiatives and technical assessments to areas of development based on fundamental understanding of genetics, molecular mechanisms, disease phenotypes and medical need in specific patient populations. We seek a cardiology-trained physician-scientist to support the early clinical development of a broad portfolio of programs in genetic heart diseases.
RESPONSIBILITIES:
  • Align mechanistic information with development goalsbased on genetics, therapeutic approach, technical likelihood of successand medical need
  • Identify high value therapeutic targets for geneticcardiac diseases and contribute clinical expertise to groups involved indisease mapping and pipeline strategy
  • Subject matter expertise in genetic cardiology bykeeping current with literature, meetings, and disease pipeline
  • Work with Research, Innovation Accelerator and BusinessDevelopment to facilitate clinical diligence of new developmentopportunities
  • Participate in scientific advisory boards convened by Companyto support the research initiatives in cardiac genetics
  • Leadership role in nominating, prioritizing andadvancing research stage programs
  • Early clinical development representation atcross-functional teams
  • Generate development plans, draft productcharacterization, first-in-human and proof of concept trial strategy,draft clinical development plans
  • Author biomarker and endpoint strategy for clinicaldevelopment
  • Early clinical representative in investigative new drug(IND) filing team

QUALIFICATIONS:
  • MD or MD/PhD required
  • Strong record of basic and/or translational researchproductivity
  • Solid foundation and interest in molecular andpopulation genetics
  • Board certified or eligible in adult or pediatriccardiology
  • Effective at building alliances across functions, basedon end-to-end drug development thinking and experience
  • Excellent interpersonal communication skills, able todrive collaborations across a matrixed organization