The duties of a work from home order taker are to receive orders from clients over the phone from a remote location. Your responsibilities in this career include submitting correct order information to the company or companies for whom you work. You may take food orders for a restaurant, orders for groceries for a supermarket, or medication orders and prescription refill orders for a pharmacy. You can also work with service providers, wholesalers, or retailers. Work at home order takers may earn commission for upselling additional products, but sales are not your primary focus.