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Weekend Physician Assistant Jobs in Raleigh, NC (NOW HIRING)

Physician Assistant

Wake Forest, NC · On-site

$85K - $116K/yr

PRN Physician Assistant - Wake Forest, NC Looking for supplemental income? Or maybe you work in a specialized setting and want to keep your full skill set sharp? At MainStreet Family Care, we're ...

Physician Assistant

Oxford, NC · On-site

$92K - $124K/yr

PRN Physician Assistant - Oxford, NC Looking for supplemental income? Or maybe you work in a specialized setting and want to keep your full skill set sharp? At MainStreet Family Care, we're growing ...

Physician Assistant

Smithfield, NC · On-site

$86K - $117K/yr

PRN Physician Assistant - Smithfield, NC Looking for supplemental income? Or maybe you work in a specialized setting and want to keep your full skill set sharp? At MainStreet Family Care, we're ...

Physician Assistant

Clayton, NC · On-site

$85K - $115K/yr

PRN Physician Assistant - Clayton, NC Looking for supplemental income? Or maybe you work in a specialized setting and want to keep your full skill set sharp? At MainStreet Family Care, we're growing ...

Physician Assistant

Raleigh, NC · On-site

$97K - $131K/yr

Attention all Physician Assistants, we are calling you to partner with us as independent ... We will primarily work weekends, with some occasional weekdays in the State of North Carolina on an ...

Physician Assistant

Raleigh, NC · On-site

$97K - $131K/yr

Attention all Physician Assistants, we are calling you to partner with us as independent ... We will primarily work weekends, with some occasional weekdays in the State of North Carolina on an ...

Physician Assistant

Raleigh, NC · On-site

$97K - $131K/yr

Description Attention all Physician Assistants, we are calling you to partner with us as ... We will primarily work weekends, with some occasional weekdays in the State of North Carolina on an ...

Physician Assistant (Spine)

Smithfield, NC · On-site

$86K - $117K/yr

With offices across North Carolina the Physician Assistant or NP role is trained and licensed to assist the supervising physician by performing diagnostic and therapeutic procedures, collecting and ...

Physician Assistant (Spine)

Smithfield, NC · On-site

$86K - $117K/yr

With offices across North Carolina the Physician Assistant or NP role is trained and licensed to assist the supervising physician by performing diagnostic and therapeutic procedures, collecting and ...

Physician Assistant (PA)

Raleigh, NC · On-site

$97K - $131K/yr

Physician's Assistant (PA) The Physician's Assistant (PA) role involves the clinician providing diagnostic and medication management services to patients of Mindology. The clinician can expect to ...

Showing results 41-60

Weekend Physician Assistant information

See Raleigh, NC salary details

$56.9K

$116.9K

$172.5K

How much do weekend physician assistant jobs pay per year?

As of Sep 2, 2026, the average yearly pay for weekend physician assistant in Raleigh, NC is $116,856.00, according to ZipRecruiter salary data. Most workers in this role earn between $97,200.00 and $131,700.00 per year, depending on experience, location, and employer.

What is a weekend physician assistant?

A Weekend Physician Assistant (PA) is a licensed medical professional who works primarily on weekends, providing patient care in hospitals, urgent care clinics, or other healthcare settings. Responsibilities include performing physical exams, diagnosing illnesses, prescribing medications, and assisting in medical procedures under a physician's supervision. These roles are ideal for PAs seeking flexible schedules or supplemental income. Weekend PAs play a crucial role in maintaining continuous patient care, especially in high-demand facilities.

What are the key skills and qualifications needed to thrive in the weekend physician assistant position, and why are they important?

To thrive as a Weekend Physician Assistant, you need a master's degree from an accredited PA program, national certification (NCCPA), and active state licensure, along with strong clinical skills in patient evaluation, diagnosis, and management. Familiarity with electronic health record (EHR) systems, diagnostic tools, and point-of-care testing is crucial for efficient documentation and patient care. Outstanding interpersonal communication, adaptability, and time management are key soft skills, as weekend shifts often require working independently and collaborating with diverse teams. These skills and credentials are essential to provide safe, effective care during off-peak hours and to ensure smooth coordination with other healthcare professionals.

What can I expect in terms of work environment and team structure as a weekend physician assistant?

As a Weekend Physician Assistant, you will typically work in a fast-paced clinical setting such as a hospital, urgent care, or large outpatient practice where weekend coverage is crucial. You’ll frequently collaborate with physicians, nurses, and allied healthcare staff, but may have a higher degree of autonomy during weekends compared to weekday shifts. Staffing levels may be leaner, requiring flexibility and proactive communication in managing patient flow and acute care scenarios. This environment offers the opportunity to build strong multidisciplinary relationships while honing your decision-making and patient management skills. Weekend roles often provide valuable experience and can serve as a stepping stone for future advancement within the healthcare organization.

What cities near Raleigh, NC are hiring for Weekend Physician Assistant jobs?

Cities near Raleigh, NC with the most Weekend Physician Assistant job openings:

Infographic showing various Weekend Physician Assistant job openings in Raleigh, NC as of August 2026, with employment types broken down into 1% As Needed, 76% Full Time, 20% Part Time, 1% Temporary, and 2% Contract. Highlights an 97% Physical, 1% Hybrid, and 2% Remote job distribution, with an average salary of $116,856 per year, or $56.2 per hour.

Physician Assistant

MainStreet Family Care

Wake Forest, NC • On-site

$85K - $116K/yr

Per diem

This job post has expired today. Applications are no longer accepted.


MainStreet Family Care rating

2.5

Company rating: 2.5 out of 10

Based on 7 frontline employees who took The Breakroom Quiz


Job description

PRN Physician Assistant - Wake Forest, NC
Looking for supplemental income? Or maybe you work in a specialized setting and want to keep your full skill set sharp?
At MainStreet Family Care, we're growing fast and looking for fast, fun, and friendly PRN Physician Assistants (PAs) to work across multiple clinics in your region. Our providers help patients feel better FAST! Boom!
This role is ideal for someone who enjoys variety, thrives in a high-volume environment, and is flexible working with different teams and clinics. New grads are encouraged to apply - haven't taken boards yet? That's okay too!
Responsibilities:
  • Urgent care, primary care, occupational medicine, and telemedicine
  • Minor procedures including toenail removals and foreign body removals
  • Suturing and splinting
  • General orthopedic evaluations and management
  • X-ray review (with Radiologist over-read)
  • EKG interpretation
  • General dermatology, eye complaints, and GYN care
  • Treating patients of all ages
  • Emergency management skills in a fast-paced setting

Schedule:
  • Shifts determined approximately two months in advance

MainStreet Clinic Hours:
  • Monday - Friday: 8:00 a.m. - 8:00 p.m.
  • Saturday & Sunday: 9:00 a.m. - 4:00 p.m.

KidsStreet Clinic Hours (select locations only):
  • Monday - Friday: 8:00 a.m. - 8:00 p.m.
  • Saturday & Sunday: 9:00 a.m. - 9:00 p.m.

Hours are subject to change based on company needs, training, float coverage, etc.
Qualifications:
  • Physician Assistant certification required prior to start date
  • Master's degree or higher required
  • Excellent written and verbal communication skills
  • EMR and Microsoft Office experience preferred

Compensation & Benefits:
  • Competitive hourly pay + bonus incentives
  • Malpractice insurance
  • $750 CME allowance annually
  • UpToDate subscription
  • Mileage reimbursement
  • Paid orientation and training

MAINSTREET FAMILY CARE IS AN EQUAL OPPORTUNITY EMPLOYER
Standard pre-employment background checks and drug screens are performed.

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