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Weekend Operating Room Nurse Jobs in O Fallon, IL

Mercy

RN Weekend - Operating Room

Saint Louis, MO · On-site

$16K/mo

Louis Hospital Main Operating Room RN Weekend- Experienced OR RNs Only! $7,500 Sign On Bonus for Experienced OR RNs Who We Are: The Main Operating Room at Mercy St. Louis Hospital is a Level I Trauma ...

Mercy

RN Weekend - Operating Room

Saint Louis, MO · On-site

$16K/mo

Louis Hospital Main Operating Room RN Weekend- Experienced OR RNs Only! $7,500 Sign On Bonus for Experienced OR RNs Who We Are: The Main Operating Room at Mercy St. Louis Hospital is a Level I Trauma ...

JobAdX

RN Weekend - Operating Room

Saint Louis, MO · On-site

$16K/mo

Louis Hospital Main Operating Room RN Weekend- Experienced OR RNs Only! $7,500 Sign On Bonus for Experienced OR RNs Who We Are: The Main Operating Room at Mercy St. Louis Hospital is a Level I Trauma ...

New

Mercy

RN Weekend - Operating Room

Saint Louis, MO · On-site

$16K/mo

Louis Hospital Main Operating Room RN Weekend- Experienced OR RNs Only! $7,500 Sign On Bonus for Experienced OR RNs Who We Are: The Main Operating Room at Mercy St. Louis Hospital is a Level I Trauma ...

Mercy

RN Weekend - Operating Room

Saint Louis, MO · On-site

$16K/mo

Louis Hospital Main Operating Room RN Weekend- Experienced OR RNs Only! $7,500 Sign On Bonus for Experienced OR RNs Who We Are: The Main Operating Room at Mercy St. Louis Hospital is a Level I Trauma ...

Mercy

RN Weekend - Operating Room

Saint Louis, MO · On-site

$16K/mo

Louis Hospital Main Operating Room RN Weekend- Experienced OR RNs Only! $7,500 Sign On Bonus for Experienced OR RNs Who We Are: The Main Operating Room at Mercy St. Louis Hospital is a Level I Trauma ...

Mercy

RN Weekend - Operating Room

Saint Louis, MO · On-site

$16K/mo

Louis Hospital Main Operating Room RN Weekend- Experienced OR RNs Only! $7,500 Sign On Bonus for Experienced OR RNs Who We Are: The Main Operating Room at Mercy St. Louis Hospital is a Level I Trauma ...

Mercy

RN Weekend - Operating Room

Saint Louis, MO · On-site

$16K/mo

Louis Hospital Main Operating Room RN Weekend- Experienced OR RNs Only! $7,500 Sign On Bonus for Experienced OR RNs Who We Are: The Main Operating Room at Mercy St. Louis Hospital is a Level I Trauma ...

Mercy

RN Weekend - Operating Room

Saint Louis, MO · On-site

$16K/mo

Louis Hospital Main Operating Room RN Weekend- Experienced OR RNs Only! $7,500 Sign On Bonus for Experienced OR RNs Who We Are: The Main Operating Room at Mercy St. Louis Hospital is a Level I Trauma ...

Mercy

RN Weekend - Operating Room

Saint Louis, MO · On-site

$16K/mo

Louis Hospital Main Operating Room RN Weekend- Experienced OR RNs Only! $7,500 Sign On Bonus for Experienced OR RNs Who We Are: The Main Operating Room at Mercy St. Louis Hospital is a Level I Trauma ...

Mercy

RN Weekend - Operating Room

Saint Louis, MO · On-site

$16K/mo

Louis Hospital Main Operating Room RN Weekend- Experienced OR RNs Only! $7,500 Sign On Bonus for Experienced OR RNs Who We Are: The Main Operating Room at Mercy St. Louis Hospital is a Level I Trauma ...

BJC

Operating Room Nurse - Experienced

Saint Louis, MO · On-site

$36.25 - $49.25/hr

Operating Room Nurse Opportunity At Barnes-Jewish Hospital, OR nurses find the kind of fast-paced environment that will test their professional judgment and critical thinking skills and encourage ...

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Weekend Operating Room Nurse information

See O Fallon, IL salary details

$15

$42

$76

How much do weekend operating room nurse jobs pay per hour?

As of Aug 29, 2026, the average hourly pay for weekend operating room nurse in O Fallon, IL is $42.41, according to ZipRecruiter salary data. Most workers in this role earn between $33.41 and $45.53 per hour, depending on experience, location, and employer.

What is a weekend operating room nurse?

Weekend Operating Room Nurses are registered nurses who specialize in providing patient care in the operating room during weekends. They are responsible for assisting surgeons, preparing the operating room, monitoring patients before, during, and after surgical procedures, and ensuring a sterile environment. These nurses work non-traditional hours, often covering shifts on Saturdays and Sundays to support hospitals that offer 24/7 surgical services. Weekend OR nurses must have strong clinical skills, the ability to work under pressure, and a thorough understanding of surgical procedures and protocols.

What are some unique challenges of working as a weekend operating room nurse compared to a weekday OR nurse?

Weekend Operating Room Nurses often handle cases with limited support staff and may need to adapt quickly to unexpected emergencies, as weekend surgeries are typically urgent or emergent rather than elective. This role requires strong collaboration skills, as nurses frequently coordinate closely with on-call surgeons, anesthesiologists, and a smaller perioperative team. Flexibility and the ability to work independently are important, as resources and immediate assistance may be more limited than during weekdays. However, many nurses find the weekend shifts offer a different pace and unique opportunities for professional growth.

What are the key skills and qualifications needed to thrive as a weekend operating room nurse, and why are they important?

To thrive as a Weekend Operating Room Nurse, you need solid clinical skills in perioperative nursing, surgical procedures, and patient assessment, usually supported by an active RN license and operating room experience. Familiarity with surgical instruments, anesthesia monitoring systems, and electronic health records (EHRs) is essential, and certifications such as CNOR (Certified Nurse Operating Room) are often preferred. Strong communication, teamwork, and the ability to stay calm under pressure are crucial soft skills, especially during high-stress surgical cases. These abilities ensure patient safety, efficient surgical workflow, and effective collaboration with surgical teams during critical weekend shifts.

What is the difference between Weekend Operating Room Nurse vs Weekend Surgical Technologist?

AspectWeekend Operating Room NurseWeekend Surgical Technologist
CredentialsRN license, OR nursing certificationCertified Surgical Technologist (CST)
Work EnvironmentHospitals, surgical centers, clinicsOperating rooms, surgical centers
Job RolePatient care, assisting during surgeries, monitoring vital signsPreparing operating rooms, passing instruments, maintaining sterile environment

Weekend Operating Room Nurses and Weekend Surgical Technologists both work in surgical settings, but nurses focus on patient care and monitoring, while technologists handle instrument preparation and sterile procedures. Both roles require specific certifications and are essential for smooth surgical operations during weekend shifts.

What cities near O Fallon, IL are hiring for Weekend Operating Room Nurse jobs?

Cities near O Fallon, IL with the most Weekend Operating Room Nurse job openings:

Weekend Operating Room Nurse jobs near you
Infographic showing various Weekend Operating Room Nurse job openings in O Fallon, IL as of August 2026, with employment types broken down into 1% As Needed, 79% Full Time, 15% Part Time, 4% Contract, and 1% Nights. Highlights an 95% Physical, 1% Hybrid, and 4% Remote job distribution, with an average salary of $88,219 per year, or $42.4 per hour.

RN Weekend - Operating Room

Saint Louis, MO • On-site

Mercy
Health Care and Social Assistance • 10K+ employees

6.5

Company rating: 6.5 out of 10

Based on 209 frontline employees who took The Breakroom Quiz

611th of 895 rated healthcare providers

People enjoy working here

Recommended by students

Recommended by parents

Learn more about Mercyexternal

$16K/mo

Full-time

Medical, Dental, Vision, Retirement, PTO

This job post has expired today. Applications are no longer accepted.

Job description

Find your calling at Mercy!Utilizes the nursing process to provide patient care. Maintains professional accountability for provision of patient care. Evaluates the overall effectiveness of care provided by other direct caregivers. Coordinates the patient care in conjunction with other departments. Maintains patient rights and confidentiality of patient information. Performs duties and responsibilities in a manner consistent with our mission, values, and Mercy Service Standards.Position Details:Join Mercy St. Louis HospitalMain Operating Room RN Weekend- Experienced OR RNs Only!

$7,500 Sign On Bonus for Experienced OR RNs

Who We Are:

The Main Operating Room at Mercy St. Louis Hospital is a Level I Trauma Center and Burn Center, delivering high-quality surgical care to patients of all ages, including pediatrics.

27 Operating Rooms

Breakdown of Teams:

  • General Surgery: general, burn, plastics, bariatric, colorectal

  • Gyn Service Line: GYN, urology, and robotics

  • Specialty Service Line: ortho & neuro

  • ENT Service Line: ENT, OMF, dental, peds, and ophthalmology

  • Off shift

At Mercy, we believe careers should align not only with your skills, but also with your heart. We support individuality, purpose, and professional growth—and we’re proud to be recognized by Modern Healthcare Magazine as one of the “Top 100 Places to Work.”

Qualifications:

Required Education:

  • Nursing degree from an accredited school

License:

  • Current Registered Nurse (RN) license in the State of Missouri

Certifications:

  • BLS required

We Offer Great Benefits!

Eligible coworkers enjoy an extensive benefits package, starting day one, including:

Financial & Career Support

  • Stay Pay Program

  • ASN to BSN Bridge Program – up to $16,000

  • BSN to MSN Bridge Program – up to $16,000

  • Tuition Reimbursement – up to $2,000 annually

  • Annual merit increases based on performance

  • Competitive salary

  • Future career growth opportunities

  • Relocation assistance available

Health & Wellness

  • Day-one medical, dental, and vision insurance

  • Paid parental leave

  • Generous PTO

  • 401(k) with employer match

  • $100/month annual contribution to eligible coworkers enrolled in the Dependent Care FSA

Questions or Interested in Learning More?

Please contact:
Stephanie Royer, Nurse Recruiter
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Why Mercy?

From day one, Mercy offers outstanding benefits - including medical, dental, and vision coverage, paid time off, tuition support, and matched retirement plans for team members working 32+ hours per pay period.

Join a caring, collaborative team where your voice matters. At Mercy, you'll help shape the future of healthcare through innovation, technology, and compassion. As we grow, you'll grow with us.

Powered by SonicJobs (an advertiser on Veritone). By applying, you consent to share your data with SonicJobs and the employer. Veritone or SonicJobs does not store or use your application data beyond facilitating the application.
See Mercy Terms & Conditions at and Privacy Policy at and SonicJobs Privacy Policy at and Terms of Use at Category:Healthcare, Keywords:Operating Room Nurse, Location:St. Louis, MO-63110

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About Mercy

Sourced by ZipRecruiter

Our mission is clear. We bring to life a healing ministry through our compassionate care and exceptional service. At Mercy, we believe in careers that match the unique gifts of unique individuals - careers that not only make the most of your skills and talents, but also your heart.

Industry

Health care and social assistance

Company size

10,000+ Employees

Headquarters location

Chesterfield, MO, US

Year founded

1827

View All Mercy Jobs

What Mercy employees say

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