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Weekend Infusion Rn Jobs in Indianapolis, IN (NOW HIRING)

Innovative Hematology

Infusion Nurse (RN)

Indianapolis, IN · On-site

$35.25 - $46.75/hr

Infusion Nurse The Infusion Nurse is responsible for the safe initiation, administration, monitoring, and discontinuation of infusion therapies. This role encompasses the provision of direct patient ...

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Weekend Infusion Rn information

See Indianapolis, IN salary details

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$43

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How much do weekend infusion rn jobs pay per hour?

As of Aug 16, 2026, the average hourly pay for weekend infusion rn in Indianapolis, IN is $43.94, according to ZipRecruiter salary data. Most workers in this role earn between $34.71 and $48.03 per hour, depending on experience, location, and employer.

What is a Weekend Infusion RN?

A Weekend Infusion RN is a registered nurse who administers intravenous (IV) therapies, medications, and treatments to patients during weekends. They work in outpatient clinics, hospitals, or home health settings, ensuring safe and effective infusion therapy. Responsibilities include monitoring patients for reactions, maintaining IV access, and educating patients about their treatments. This role requires strong IV skills, attention to detail, and the ability to work independently. It is ideal for nurses seeking flexible weekend hours while providing critical care to patients requiring infusion services.

What are the typical responsibilities and work environment for a Weekend Infusion RN?

As a Weekend Infusion RN, you will primarily administer intravenous medications, monitor patients for side effects, and educate them about their treatment plans—often in outpatient clinics, specialty centers, or sometimes patients' homes. The work environment is usually focused and patient-centered, with collaboration between RNs, pharmacists, and physicians, especially for complex cases. Since the role is concentrated on weekends, you may work more independently and manage a smaller, more specialized patient load. This schedule offers flexibility and the opportunity to focus on building relationships with patients receiving ongoing infusion therapy.

What are the key skills and qualifications needed to thrive in the Weekend Infusion RN position, and why are they important?

Weekend Infusion RNs require a current RN license, strong IV therapy skills, and experience in administering infusion medications safely. Familiarity with infusion pumps, electronic health records (EHR), and up-to-date certifications like Basic Life Support (BLS) or Advanced Cardiac Life Support (ACLS) are typically expected. Excellent organizational skills, compassionate bedside manner, and the ability to work independently are valuable soft skills in this setting. Mastery of these competencies ensures reliable, high-quality patient care during weekends when resources may be limited.

Do infusion nurses get paid more?

Infusion nurses often earn higher wages compared to general nursing roles due to specialized skills in administering IV therapies and managing complex patient needs. Their compensation can also increase with experience, certifications, and working in high-demand settings or during overtime and weekend shifts. However, pay varies by location, employer, and individual qualifications.

What are the most commonly searched types of Infusion Rn jobs in Indianapolis, IN?

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What cities near Indianapolis, IN are hiring for Weekend Infusion Rn jobs?

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Weekend Infusion Rn jobs near you
Infographic showing various Weekend Infusion Rn job openings in Indianapolis, IN as of August 2026, with employment types broken down into 1% As Needed, 69% Full Time, 25% Part Time, 4% Contract, and 1% Nights. Highlights an 94% Physical, 1% Hybrid, and 5% Remote job distribution, with an average salary of $91,387 per year, or $43.9 per hour.

Home Infusion RN - Indianapolis, IN

Float Health, Inc.

Indianapolis, IN • On-site

$65 - $75/hr

Full-time

Re-posted 18 days ago

Job description

Are you an infusion center or oncology nurse looking for a flexible side gig? Are you a critical care RN or ER nurse interested in taking care of patients outside of the hospital? We are here for YOU!

Float Health is an on-demand nursing service company. Float partners with specialty pharmacies to connect patients and nurses for in-home medication administration. Each nurse works as an independent nurse contractor to provide patients with IV medications, including IVIGs and monoclonal antibodies. All jobs are when you want them, where you want them, and the best part is you get to choose your schedule. There is never any obligation to accept a job!

Previous job experience required:

  • 3-5+ years of hospital-based nursing or home infusion/infusion center

Responsibilities include:

  • Providing one-on-one patient care and education in the comfort of their own home
  • Utilize your clinical IV skills by placing and maintaining PIVs
  • Administer IV infusions and medications to patients in a safe and efficient manner

Previous job experience preferred:

  • Emergency Department, Infusion Center, Preoperative, Infusion Home Health, Critical Care, Transport

Required Education:

  • RN or BSN

Required Documents:

  • Current Active State Registered Nursing License or Compact Nurse License (NLC)
  • Current BLS
  • Proof of Nursing Liability Insurance

https://www.youtube.com/watch?v=GQcRgAAJUfU&t=8s

Pay: $65.00 - $75.00 per hour

Medical Specialty:

  • Allergy & Immunology
  • Critical & Intensive Care
  • Emergency Medicine
  • Hematology
  • Home Health
  • Infectious Disease
  • Oncology

Supplemental Pay:

  • Completion bonus
  • Referral bonus

Experience:

  • Hospital Nursing: 3 years (Required)

License/Certification:

  • BLS Certification (Required)
  • RN License (Required)

Work Location:

  • On the road