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Weekend Histology Technician Jobs in Rochester, MN

Mayo Clinic

Histotech Assistant - Histology

Rochester, MN

$23.29 - $33.36/hr

You must work towards completion of MCSHS Histology Technician program prerequisites: Prerequisites - Application Process - Mayo Clinic College of Medicine & Science Additional Requirements * Medical ...

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Weekend Histology Technician information

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How much do weekend histology technician jobs pay per hour?

As of Aug 31, 2026, the average hourly pay for weekend histology technician in Rochester, MN is $35.62, according to ZipRecruiter salary data. Most workers in this role earn between $25.91 and $42.26 per hour, depending on experience, location, and employer.

What is a weekend histology technician?

A Weekend Histology Technician is responsible for preparing and processing tissue samples in a laboratory setting, specifically working on weekends. They embed, section, stain, and analyze samples to assist pathologists in diagnosing diseases. This role requires knowledge of histology techniques, laboratory equipment, and safety procedures. It often suits individuals seeking part-time or flexible work schedules while still contributing to critical medical diagnostics.

What are the key skills and qualifications needed to thrive as a weekend histology technician?

To excel as a Weekend Histology Technician, you typically need a background in laboratory sciences, knowledge of tissue processing and staining techniques, and experience with histology equipment. Familiarity with laboratory information systems (LIS), microtomes, and compliance protocols such as CAP or CLIA is highly valued, along with relevant certifications like HT(ASCP). Attention to detail, strong organizational skills, and reliability are important soft skills in this field. These qualifications and attributes ensure accurate specimen preparation, efficient workflow, and adherence to safety and quality standards during weekend lab operations.

What are the typical responsibilities and work environment for a weekend histology technician?

As a Weekend Histology Technician, your main duties include preparing tissue samples, embedding and sectioning specimens, performing stains, and ensuring all slides are ready for pathologist review. You will often work independently or with a small team in a clinical laboratory setting, maintaining strict quality controls and following safety protocols due to reduced weekend supervision. Effective communication with pathologists and other lab staff is crucial for timely and accurate diagnoses. This role is ideal for those who enjoy hands-on laboratory work and require a more flexible schedule while still contributing significantly to patient care.

Are weekend histology technicians in demand?

Weekend histology technicians are in demand due to the need for continuous laboratory operations in healthcare and research settings. Employers often seek technicians with certification and experience to cover weekend shifts, especially in hospitals and diagnostic labs that operate 24/7.

Where do weekend histology technicians make the most money?

Weekend histology technicians tend to earn higher wages in regions with a higher cost of living and greater demand for healthcare services, such as metropolitan areas or regions with large medical centers. Salaries can also increase with experience, certifications, and working in specialized or high-volume laboratories. However, pay varies widely based on geographic location and employer, so researching local job markets provides the most accurate information.

What are the most commonly searched types of Histology Technician jobs in Rochester, MN?

The most popular types of Histology Technician jobs in Rochester, MN are:

What job categories do people searching Weekend Histology Technician jobs in Rochester, MN look for?

The top searched job categories for Weekend Histology Technician jobs in Rochester, MN are:

Weekend Histology Technician jobs near you
Infographic showing various Weekend Histology Technician job openings in Rochester, MN as of August 2026, with employment types broken down into 1% As Needed, 81% Full Time, 14% Part Time, 3% Contract, and 1% Nights. Highlights an 99% Physical, and 1% Remote job distribution, with an average salary of $74,098 per year, or $35.6 per hour.

Histology Technician or Histotechnologist (HT/HTL) - Neurology

Rochester, MN • On-site

Mayo Clinic
Hospitals • 10K+ employees

7.8

Company rating: 7.8 out of 10

Based on 705 frontline employees who took The Breakroom Quiz

133rd of 896 rated healthcare providers

People enjoy working here

Good employer

Recommended by students

Learn more about Mayo Clinicexternal

$32.43 - $48.66/hr

Full-time

Medical, Dental, Vision, Retirement

Re-posted 2 hours ago

Job description

Why Mayo Clinic

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans - to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.

Benefits Highlights
  • Medical: Multiple plan options.
  • Dental: Delta Dental or reimbursement account for flexible coverage.
  • Vision: Affordable plan with national network.
  • Pre-Tax Savings: HSA and FSAs for eligible expenses.
  • Retirement: Competitive retirement package to secure your future.

Responsibilities

Mayo Clinic is seeking Histology Technicians and Histotechnologists (HT/HTL) to join a dynamic and collaborative team within Neurology.

The Neurology Laboratories at Mayo Clinic process a high volume of peripheral nerve specimens. Our laboratories take pride in contributing to accurate patient diagnoses and advancing scientific knowledge through collaboration with pathologists, clinicians, and research investigators.

As an HT/HTL, you will play a critical role in preparing high-quality slides for pathologist review. Responsibilities may include embedding, microtomy, cryotomy, special staining, immunohistochemical techniques, and handling of fresh and complex specimens. The work requires attention to detail, adaptability, and a commitment to quality and patient care.

In addition, you will:

  • Support training and onboarding of students and new employees
  • Collaborate across multidisciplinary teams to ensure timely and accurate results
  • Contribute to a respectful, inclusive, and team-oriented work environment
  • Adapt to the unique demands and workflows of different subspecialty laboratories
     

Mayo Clinic offers extensive opportunities for professional growth and career advancement . Whether you are interested in developing technical expertise across multiple lab areas or specializing in a particular discipline, this role provides a strong foundation for long-term career development.

Don't miss the opportunity to be part of a team dedicated to excellence in patient care, innovation, and laboratory medicine.

Histology Technician / Histotechnologist (HT/HTL)

As a Histology Technician or Histotechnologist, you will perform a variety of technical procedures to prepare high-quality microscopic slide preparations used by pathologists for diagnostic and prognostic evaluation.

These procedures may include:

  • Specimen accessioning and identification
  • Specimen processing and embedding
  • Microtomy techniques, including: 
    • Paraffin
    • Frozen (cryotomy)
    • Plastic sections
  • Routine Hematoxylin and Eosin (H&E) staining
  • Special stains
  • Immunofluorescence
  • Immunohistochemical (IHC) staining
  • In situ hybridization

This vacancy is not eligible for sponsorship, and we will not sponsor or transfer visas for this position. 


Qualifications

Histology Technician (HT):

  • Associate degree required.
  • Coursework including 24 semester hours of the following: 
    • A minimum of 12 credit hours in chemistry, biology, or medical laboratory technology
    • 6 credit hours in chemistry
    • 6 credit hours in biology
  • Histology Technician (HT) certified by the American Society of Clinical Pathologists (ASCP) required by start date
     

Histotechnologist (HTL):

  • Bachelor's degree required.
  • Histotechnologist (HTL) certified by the American Society of Clinical Pathologists (ASCP) required by start date

Additional Qualifications

  • Graduate of a NAACLS accredited program preferred. 
  • Graduates of the Mayo Clinic School of Health Sciences Histology Technician Program will receive preference.
  • Ability to accommodate scheduling adjustments, off shifts, holidays, on-call, and weekend work assignments.
     

*Employees obtaining certification(s) after January 1, 2004, will be required to demonstrate evidence of ongoing maintenance of certification.


Exemption Status
Nonexempt
Compensation Detail
The pay range for Histology Technician is $26.52 - $39.32 per hour. The pay range for Histotechnologist is $32.43 - $48.66 per hour.
Benefits Eligible
Yes
Schedule
Full Time
Hours/Pay Period
80
Schedule Details
This is a daytime position Monday through Friday. Hours are slightly flexible but will be within 7 AM to 4:30 PM
Weekend Schedule
While weekend hours may be needed based on workload, there are no scheduled weekend hours at this time. There is a potential for weekend coverage once training is complete, but again nothing permanent at this time.
International Assignment
No
Site Description
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is. 

Equal Opportunity

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the 'EOE is the Law'.  Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.

Recruiter
Casie JohnsonQualifications:

Histology Technician (HT):

  • Associate degree required.
  • Coursework including 24 semester hours of the following: 
    • A minimum of 12 credit hours in chemistry, biology, or medical laboratory technology
    • 6 credit hours in chemistry
    • 6 credit hours in biology
  • Histology Technician (HT) certified by the American Society of Clinical Pathologists (ASCP) required by start date
     

Histotechnologist (HTL):

  • Bachelor's degree required.
  • Histotechnologist (HTL) certified by the American Society of Clinical Pathologists (ASCP) required by start date

Additional Qualifications

  • Graduate of a NAACLS accredited program preferred. 
  • Graduates of the Mayo Clinic School of Health Sciences Histology Technician Program will receive preference.
  • Ability to accommodate scheduling adjustments, off shifts, holidays, on-call, and weekend work assignments.
     

*Employees obtaining certification(s) after January 1, 2004, will be required to demonstrate evidence of ongoing maintenance of certification.

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About Mayo Clinic

Sourced by ZipRecruiter

Mayo Clinic is the largest integrated, not-for-profit medical group practice in the world. We're building the future, one where the best possible care is available to everyone — and more people can heal at home. Our relentless research turns into earlier diagnoses and new cures. That's how we inspire hope in those who need it most. At Mayo Clinic, experts work together to solve the most challenging unmet needs of patients. Our history of innovation dates back almost 150 years, when brothers Will and Charlie Mayo pioneered an integrated, team-based approach to medicine. Today, that trailblazing spirit drives innovations like Mayo Clinic Platform — which powers new technologies to change how care is delivered to all.

Industry

Hospitals

Company size

10,000+ Employees

Headquarters location

Rochester, MN, US

Year founded

1919

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