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Vivo Scientist information

What is a vivo scientist?

Vivo Scientists are researchers who specialize in conducting experiments and studies involving living organisms, such as animals or humans, to understand biological processes and disease mechanisms. Their work is crucial in fields like drug development, toxicology, and biomedical research. They use in vivo (within the living) models to assess the effects of drugs, treatments, or interventions before they progress to clinical trials. Vivo Scientists often collaborate with other scientists and must adhere to ethical guidelines and regulations governing animal or human research.

What skills and qualifications are needed to thrive as a vivo scientist?

To thrive as a Vivo Scientist, you need a solid background in biology or related fields, with expertise in in vivo experimental techniques and often a relevant advanced degree. Familiarity with laboratory animal handling, data analysis software, and compliance with animal care regulations is typically required. Attention to detail, problem-solving, and effective teamwork are crucial soft skills for this position. These competencies ensure rigorous, ethical research and reliable experimental results in preclinical studies.

What are common challenges a vivo scientist faces when managing in vivo studies, and how can they be addressed?

A key challenge for Vivo Scientists is ensuring the reproducibility and reliability of animal study results, which requires meticulous planning, precise dosing, and strict adherence to ethical guidelines. Coordinating with cross-functional teams—such as veterinarians, regulatory staff, and data analysts—can also be complex, as it involves clear communication and thorough documentation. Proactively addressing these challenges through detailed protocols, regular team meetings, and ongoing training helps maintain high scientific and ethical standards, while promoting efficient project progress.

What is the difference between Vivo Scientist vs In Vitro Scientist?

AspectVivo ScientistIn Vitro Scientist
Required CredentialsBachelor's or Master's in Biology, Pharmacology, or related fields; lab experienceBachelor's or Master's in Biology, Biochemistry, or related fields; lab experience
Work EnvironmentAnimal facilities, live animal studies, in vivo experimentsLaboratories focusing on cell cultures, biochemical assays, in vitro experiments
Industry UsagePharmaceutical, biotech, academic research involving live modelsPharmaceutical, biotech, academic research involving cell-based assays
Common Search/ComparisonVivo Scientist vs In Vitro Scientist

The main difference between a Vivo Scientist and an In Vitro Scientist lies in their focus: Vivo Scientists conduct experiments involving live animals or organisms, while In Vitro Scientists work with cell cultures and biochemical assays outside of living organisms. Both roles require similar educational backgrounds and are essential in biomedical research, but they differ in work environment and experimental methods.

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Vivo Scientist jobs near you
Infographic showing various Vivo Scientist job openings in the United States as of August 2026, with employment types broken down into 1% Internship, 1% As Needed, 84% Full Time, 10% Part Time, and 4% Contract. Highlights an 84% Physical, 3% Hybrid, and 13% Remote job distribution.

Principal Scientist II - Pharmacology

Cambridge, MA • On-site

Novartis Pharmaceuticals Corporation
10K+ employees
Learn more about Novartis Pharmaceuticals Corporationexternal

$126K - $234K/yr

Full-time

Medical, Life, Retirement, PTO

Re-posted 13 days ago

Job description

Band

Level 4


Job Description Summary

#LI-Onsite
Location: Cambridge, MA
This position is located in Cambridge, MA and does not have the ability to be located remotely. Please only apply if this area is accessible to you.
Over 40 therapies in the clinic! NIBR Oncology strives to reimagine medicines for cancer patients through a combination of treatment approaches including targeted therapies, immunotherapies, CAR-T, and radioligand therapy. NIBR is seeking an in vivo scientist to join our Oncology Pharmacology team in Cambridge, MA. The successful candidate will join a dynamic, multi-disciplinary team and play a key role in the development and application of in vivo models for evaluating novel cancer therapies and advancing the early-stage drug discovery pipeline. This is a labhead-based position, where the ideal candidate is expected to lead efforts in the design and execution of in vivo anti-tumor efficacy and PK/PD studies aimed at evaluating drug candidates in CDX, PDX, and syngeneic models. Applicants are expected to develop novel in vivo assays to interrogate key scientific questions and deliver high-value translationally relevant data that can inform clinical development. Qualified candidates will have extensive experience in a variety of molecular biology skills. A strong background and expertise in antibody drug conjugates is preferred. We are looking for highly motivated, inquisitive, and creative individuals, who thrive in a highly matrixed work environment, and can effectively communicate within multidisciplinary project teams.


Job Description

Responsibilities:

  • Design pre-clinical in vivo studies to explore novel hypotheses, screen candidate molecules, and establish proof-of-concept of new modalities

  • Develop in vivo CDX, PDX, and syngeneic models to evaluate anti-tumor activity, PK/PD relationships, relevant biomarkers, and key translational questions

  • Manage associate-level scientists

  • Collaborate with cross-functional project teams

  • Critically analyze and present results within a multidisciplinary team environment

  • Careful adherence to animal protocols and proper documentation of data and methods in electronic laboratory notebook

Qualifications:

  • PhD with 5-8 years of research experience as a postdoc or in the pharmaceutical/biotech industry

  • Deep knowledge of antibody drug conjugates

  • Extensive experience working with CDX and PDX xenograft tumor models and/or syngeneic models

  • Expertise in cell culture, PCR, ELISA, western blot, and flow cytometry

  • Strong analytical, communication (written and verbal), and organizational skills, including a proficiency with PowerPoint and commonly used data analysis programs, such as Prism and Excel

Novartis Compensation and Benefit Summary:

The salary for this position is expected to range between $126,000 and $234,000 per year.

The final salary offered is determined based on factors like, but not limited to, relevant skills and

experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published

salary range based on company and market factors.

Your compensation will include a performance-based cash incentive and, depending on the level of the

role, eligibility to be considered for annual equity awards.

US-based eligible employees will receive a comprehensive benefits package that includes health, life and

disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves.


EEO Statement:

The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.


Accessibility and reasonable accommodations

The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please send an e-mail to tas.nacomms@novartis.com call +1 (877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
https://www.novartis.com/careers/careers-research/notice-all-applicants-us-job-openings


Salary Range

$126,000.00 - $234,000.00


Skills Desired

Analytical Skill (Inactive), Analytical Skill (Inactive), Analytical Thinking, Chemical Biology, Chemistry, Clinical Trials, Collaboration, Communication Skills (Inactive), Curious Mindset, Data (Inactive), Data Analysis, Design of Experiments (DOE), Detail-Oriented, Drug Development, Drug Discovery Process, Ethics, Gene Therapy, Immunology, Inventory Management, Laboratory (Inactive), Leading Project Teams, Lifesciences (Inactive), Machine Learning (ML), Management (Inactive), Medical Research {+ 10 more}

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