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Usa Python Jobs in Downingtown, PA (NOW HIRING)

AI-ML Tech Lead

Wilmington, DE · On-site

$42K - $55K/yr

... Python, TypeScript, or Java. • Experience with cloud-native architectures (AWS/Azure/GCP ... Founded in 2010, the company is headquartered in Iselin, USA, with a team of 501-1000 employees.

... Python, Java Spring Boot, .Net, etc.) • Experience and exposure to observability tools such as ... Founded in 2000, the company is headquartered in New York, USA, with a team of 10001+ employees.

Site Reliability Engineer

King Of Prussia, PA · On-site

$56.75 - $75.50/hr

Proficiency in scripting and automation (e.g., Bash, Python, Go) and software engineering concepts ... Must be a USA Citizen or be in process to become one by January 2027 * Ability to take a rotating ...

IS Developer

Exton, PA · On-site +1

Development experience using Python, Java, JavaScript, and/or Microsoft .NET * Working knowledge of ... USA * Comprehensive Medical, Dental, and Vision insurance plans * 401K, including company match

Strong scripting experience (Python preferred) * Experience operating security platforms at ... We have won several employer recognition awards, including Top Workplace USA, Great Places to Work ...

New

... a top workplace by USA Today, Fortune , The American Lawyer, Vault and others. We are also ... Strong SQL and Python skills, with experience building scalable workflows, structured data ...

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Usa Python information

See Downingtown, PA salary details

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How much do usa python jobs pay per hour?

As of Aug 10, 2026, the average hourly pay for usa python in Downingtown, PA is $60.78, according to ZipRecruiter salary data. Most workers in this role earn between $50.10 and $69.04 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Python developer?

To thrive as a Python Developer, you need strong programming skills in Python, understanding of software development principles, and often a degree in computer science or related fields. Familiarity with frameworks like Django or Flask, version control systems such as Git, and experience with databases are typically required. Problem-solving ability, attention to detail, and effective communication are essential soft skills for collaborating with teams and troubleshooting code. These skills and qualifications ensure the delivery of robust, scalable, and maintainable software solutions.

What are some common challenges faced by Python developers working in the USA, and how can they overcome them?

Python developers in the USA often encounter challenges such as keeping up with rapidly evolving technologies, integrating Python with legacy systems, and collaborating across multidisciplinary teams. To overcome these hurdles, it's important to stay updated with industry trends through continuous learning, participate in code reviews, and leverage robust testing practices. Additionally, effective communication and teamwork are vital for integrating solutions and ensuring project success in diverse, agile environments.

What does a Python developer do in the USA?

A Python developer in the USA primarily writes, tests, and maintains code using the Python programming language. They work on a variety of projects, including web development, data analysis, machine learning, automation, and scripting. Python developers often collaborate with other team members to design software solutions, debug applications, and ensure the performance and scalability of their code. Their roles can vary depending on the industry, ranging from building backend web services to analyzing big data or developing artificial intelligence models.

How much do Python programmers make in the US?

Python programmers in the US typically earn an average salary ranging from $70,000 to $120,000 annually, depending on experience, location, and industry. Entry-level roles may start around $60,000, while senior positions with specialized skills or certifications can exceed $130,000. Knowledge of frameworks, data analysis, or machine learning can influence earning potential.

What is the difference between Usa Python vs Usa Data Analyst?

AspectUsa PythonUsa Data Analyst
Required SkillsPython programming, data manipulation, scriptingData visualization, statistical analysis, Excel
Work EnvironmentSoftware development, data engineering teamsBusiness units, reporting teams
CertificationsPython certifications, data science coursesExcel, Tableau, SQL certifications

While both roles involve working with data, Usa Python focuses on coding, automation, and data engineering tasks, whereas Usa Data Analyst emphasizes interpreting data, creating reports, and visualizations. The roles often collaborate but serve different functions within data projects.

What job categories do people searching Usa Python jobs in Downingtown, PA look for? The top searched job categories for Usa Python jobs in Downingtown, PA are:
What cities near Downingtown, PA are hiring for Usa Python jobs? Cities near Downingtown, PA with the most Usa Python job openings:

Senior Director, Agentic AI and Automation

Madrigal Pharmaceuticals

Conshohocken, PA • On-site

Full-time

Re-posted 19 days ago


Job description

Job Summary:
Madrigal Pharmaceuticals is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH). They are seeking a Senior Director for Agentic AI and Automation to lead the vision and deployment of AI-enabled workflows that enhance decision-making and operational efficiency across various functions.
Responsibilities:
• Define and execute a multi‑year agentic AI & RPA roadmap converging hyperautomation, process‑mining, and LLM‑driven workflows.
• Operationalize an Agentic Automation Center of Excellence (CoE) governing standards, reusable assets, and ROI tracking.
• Partner with cross‑functional executives to prioritise high‑value automations across the business.
• Define and execute a multi‑year roadmap converging agentic AI, RPA, and process‑mining.
• Operationalize an Agentic Automation CoE—governing standards, reusable templates, and ROI tracking.
• Partner with executive stakeholders to prioritise high‑value automations (clinical, commercial, PV, manufacturing).
• Champion MCP and agent‑orchestration patterns for future‑proof integration.
• Architect modular multi‑agent systems powered by frontier LLMs and leading agent frameworks (LangChain family, AutoGen, CrewAI, etc.).
• Design secure agent‑to‑agent (A2A) communication with shared memory, credential vaults, RBAC.
• Implement enterprise MCP engine and Agent Protocol standards enabling human–agent–bot collaboration.
• Standardise integration with vector stores and cloud MLOps platforms (Azure AI Search, Databricks, SageMaker, Vertex AI).
• Build event‑driven, low‑code pipelines (n8n, Dify, Glean) to trigger agentic RPA tasks in real time.
• Implement observability and governance (Arcade.dev, AgentOps, Langfuse).
• Establish robust testing harnesses and GxP‑compliant validation for every autonomous workflow.
• Leverage process‑ & task‑mining insights to auto‑generate automation backlogs and measure value.
• Lead a multi‑disciplinary squad of AI automation architects, prompt engineers, and product managers.
• Drive iterative product delivery using agile OKRs, rapid POCs, and continual KPI evaluation.
• Experiment with cutting‑edge agent research (ReWOO, SuperAGI, CAMEL) and open‑source Agentic RPA.
• Collaborate with open‑source communities, cloud partners, and leading vendors.
• Set standards for agent safety, ethical AI, and closed‑loop feedback.
• Forge deep partnerships with Enterprise Data, IT Infrastructure, and Cybersecurity teams.
Qualifications:
Required:
• Advanced degree (Ph.D. preferred) in AI, Data Science, Computer Science, Applied Mathematics, Engineering, Physics, or related field.
• 15+ years leading AI/ML or intelligent‑automation initiatives; 10+ years hands‑on with Python, SQL, R, MATLAB, PyTorch, Keras, Git.
• 12+ years architecting ML/deep‑learning solutions incl. LLMs (GPT‑4, BERT, LLaMA, Dolly) and RAG pipelines.
• 8+ years building web apps (Dash, Streamlit, Shiny) and advanced data products.
• 8+ years implementing scalable AI/ML on platforms like Databricks or Dataiku, with strong AI/MLOps.
• Deep knowledge of cloud data platforms (AWS, Azure, GCP) and compliance (GxP, HIPAA, GDPR).
• Strong theoretical foundation in ML/AI with contributions to papers and presentations.
• Exceptional written & verbal communication skills translating complex research to executives.
• Extensive leadership experience managing cross‑functional technology teams in regulated industries.
Company:
Madrigal Pharmaceuticals is a biopharmaceutical company developing therapeutics for the treatment of cardiovascular-metabolic diseases. Founded in 2016, the company is headquartered in Conshohocken, USA, with a team of 501-1000 employees. The company is currently Late Stage.