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Upstream Process Development Research Associate Jobs in Boston, MA

Amgen

Process Development Associate

Cambridge, MA · On-site

... we research, manufacture, and deliver innovative medicines to help people live longer, fuller ... Perform small-scale bioprocess experiments that encompass both upstream (cell culture) and ...

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All JobsUpstream Process Development Research Associate JobsUpstream Process Development Research Associate Jobs in Boston, MA

Upstream Process Development Research Associate information

See Boston, MA salary details

$20

$36

$53

How much do upstream process development research associate jobs pay per hour?

As of Sep 10, 2026, the average hourly pay for upstream process development research associate in Boston, MA is $36.59, according to ZipRecruiter salary data. Most workers in this role earn between $30.05 and $44.90 per hour, depending on experience, location, and employer.

What is the difference between Upstream Process Development Research Associate vs Downstream Process Development Research Associate?

AspectUpstream Process Development Research AssociateDownstream Process Development Research Associate
Primary FocusDeveloping and optimizing cell culture and fermentation processesPurification and recovery of bioproducts from cell cultures
Required SkillsBioprocessing, cell biology, fermentation techniquesChromatography, filtration, purification methods
Work EnvironmentLaboratories, bioreactors, pilot plantsLaboratories, purification facilities
Industry UsageBiotech, pharmaceutical manufacturingBiotech, pharmaceutical manufacturing

Both roles are essential in bioprocess development, with upstream associates focusing on cell culture processes and downstream associates handling product purification. They often collaborate but require different technical skills aligned with their specific stages in bioprocessing.

Infographic showing various Upstream Process Development Research Associate job openings in Boston, MA as of September 2026, with employment types broken down into 96% Full Time, and 4% Contract. Highlights an 96% In-person, 2% Hybrid, and 2% Remote job distribution, with an average salary of $76,114 per year, or $36.6 per hour.

Research Associate - Process Development

Watertown, MA • On-site

Artis BioSolutions
See more jobs at Artis BioSolutionsexternal

Full-time

Re-posted 3 days ago

Job description

The Process Development department at Landmark Bio/Artis BioSolutions supports a growing portfolio of advanced cell and gene therapies (CGT), including CAR-T, iPSC, AAV, LVV, and synthetic DNA products. We are immediately hiring a highly motivated Research Associate - Process Development to support the development and optimization of innovative manufacturing processes for advanced therapies.
In this role, you will execute hands-on cell culture and process development experiments, maintain cell lines, optimize culture conditions, analyze experimental data, and support the development and scale-up of robust manufacturing processes. You will collaborate closely with Process Development, Analytical Development, Manufacturing, Engineering, and Quality teams to advance programs from development through technology transfer and GMP manufacturing.
This is an exciting opportunity to join a fast-paced, collaborative team focused on translating cutting-edge research into life-changing medicines. This hands-on, lab-based role requires working on-site at Landmark Bio/Artis BioSolutions in Watertown, MA, with a flexible schedule based on experimental needs.
Responsibilities
  • Cell Culture: Perform mammalian cell culture activities including aseptic technique, media and buffer preparation, culture initiation, propagation, expansion, and cryopreservation.
  • Cell-Based Process Development: Culture and process a variety of cell types, including iPSC, MSC, and primary human cells.
  • Bioreactor Operations: Support the operation, monitoring, and optimization of bioreactor systems and associated upstream processes.
  • Genetic Manipulation: Perform cell transfection, transduction, and other genetic modification techniques using relevant viral and non-viral systems.
  • Process Optimization: Execute experiments to evaluate and optimize culture conditions, process parameters, yields, and overall process performance.
  • Experimental Execution: Prepare and execute laboratory protocols, collect samples, analyze experimental results, and troubleshoot technical challenges.
  • Technology Transfer: Support process scale-up, engineering runs, and transfer of developed processes into GMP manufacturing.
  • Documentation: Maintain accurate and reliable records including electronic laboratory notebooks, batch records, databases, protocols, and other technical documentation.
  • Technical Writing: Draft and/or contribute to SOPs, protocols, batch records, technical reports, and process development documentation.
  • Laboratory Operations: Perform routine laboratory activities including equipment maintenance, inventory management, and maintaining laboratory readiness.
  • Safety & Compliance: Follow all environmental health and safety, infection control, quality, and applicable regulatory requirements.
Qualifications
  • Education: Bachelor's degree in Biology, Bioengineering, Biotechnology, Biochemistry, Chemical Engineering, or a related scientific discipline.
  • Experience: 1-2+ years of relevant laboratory, biotechnology, or process development experience. Equivalent advanced-degree academic research experience may also be considered.
  • Cell Culture: Strong understanding of mammalian cell culture and aseptic techniques.
  • Technical Experience: Hands-on experience with cell culture, cell expansion, cryopreservation, transfection, transduction, or related process development techniques.
  • Viral Vectors: Willingness to work with viral vector systems, including lentiviral and AAV vectors, as well as biological samples.
  • Bioprocessing: Experience with bioreactors and/or other cell-based process development technologies is preferred.
  • Problem-Solving: Strong analytical and troubleshooting skills with the ability to interpret experimental data and contribute to process improvements.
  • Collaboration: Highly motivated team player who can also work independently in a fast-paced laboratory environment.
  • Communication: Strong verbal and written communication skills with excellent attention to detail

Landmark Bio/Artis BioSolutions is an Equal Opportunity, Affirmative Action employer. Minorities, women, veterans, and individuals with disabilities are encouraged to apply.
We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.

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