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Uplc Jobs (NOW HIRING)

Scientist

Baltimore, MD ยท On-site

HPLC/UPLC method development and validation experience is desired Experience with mammalian cell culture media, supplements and feeds is a differentiator. Excellent communication and interpersonal ...

Analytical Chemist

Sunnyvale, CA ยท On-site

$24 - $29/hr

Interpret chromatographic data from HPLC/UPLC and GC-MS instruments. * Identify, troubleshoot, and report manufacturing issues while recommending effective corrective actions. * Communicate ...

Scientist-I

Rahway, NJ ยท On-site

$66K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

The ideal candidate would possess: โ€ข Experience in modern liquid chromatography (Agilent UPLC preferably with Open Lab CDS) โ€ข Experience in preparing and analyzing samples for solubility ...

Analytical Chemist

Sunnyvale, CA ยท On-site

$24 - $29/hr

Interpret chromatographic data from HPLC/UPLC and GC-MS instruments. * Identify, troubleshoot, and report manufacturing issues while recommending effective corrective actions. * Communicate ...

Research Scientist 4

Staten Island, NY ยท On-site

$110K - $135K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

PRIMARY RESPONSIBILITIES: โ€ข Ability to successfully operate a UPLC (ultra performance liquid chromatography) mass spectrometry (UPLC-MS) system โ€ข Facilitate successful data extraction for ...

Perform analytical testing of raw materials, intermediates, finished products, and APIs using techniques such as HPLC, UPLC, GC, FTIR, KF, NMR, and other laboratory methods * Review, analyze, and ...

Research Scientist 4

Staten Island, NY

$110K - $135K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Ability to successfully operate a UPLC (ultra performance liquid chromatography) mass spectrometry (UPLC-MS) system Facilitate successful data extraction for analysis and engage in productive ...

$28 - $31/hr

AKTA, LC-MS, UPLC, LTQ, QDA analytical instruments are used. This person will assist with training new staff, work on multiple projects simultaneously and stay current with new modifications of ...

New

$28 - $31/hr

AKTA, LC-MS, UPLC, LTQ, QDA analytical instruments are used. This person will assist with training new staff, work on multiple projects simultaneously and stay current with new modifications of ...

New

Showing results 41-60

UPLC information

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$28.5K

$59.6K

$100K

How much do uplc jobs pay per year?

As of Aug 16, 2026, the average yearly pay for uplc in the United States is $59,606.00, according to ZipRecruiter salary data. Most workers in this role earn between $45,500.00 and $69,000.00 per year, depending on experience, location, and employer.

What are some common challenges encountered by UPLC operators, and how can they be addressed?

UPLC operators often face challenges such as dealing with instrument maintenance, troubleshooting unexpected results, and managing complex sample matrices. Ensuring proper calibration and regular maintenance of the system can prevent many technical issues. Additionally, thorough training on method development and data analysis helps operators quickly identify and resolve anomalies, leading to more reliable results. Collaborating closely with chemists and laboratory technicians can also facilitate problem-solving and knowledge sharing within the team.

What are the key skills and qualifications needed to thrive as a UPLC specialist?

To thrive as a UPLC Specialist, you need a solid background in analytical chemistry, laboratory techniques, and experience with chromatographic separation, usually supported by a relevant science degree. Proficiency in operating UPLC instruments, chromatographic data software (such as Empower or Chromeleon), and understanding regulatory requirements like GLP or GMP are commonly expected. Attention to detail, problem-solving, and strong organizational skills help professionals excel in troubleshooting and managing complex analytical workflows. These competencies ensure accurate data generation, compliance, and high-quality results in research or quality control environments.

What is UPLC?

UPLC stands for Ultra Performance Liquid Chromatography. It is an advanced form of liquid chromatography that uses columns with smaller particle sizes and higher pressures to achieve faster, more sensitive, and more efficient separation of compounds in a mixture. UPLC is commonly used in pharmaceutical, environmental, and food industries for qualitative and quantitative analysis. Its high resolution and speed make it a preferred technique for analyzing complex samples with precision.

What is the difference between Uplc vs UPLC Developer?

AspectUplcUPLC Developer
CredentialsTypically requires knowledge of Uplc language and blockchain fundamentalsRequires expertise in Uplc, smart contract development, and blockchain protocols
Work EnvironmentBlockchain projects, smart contract coding, testing, and deploymentDeveloping, testing, and maintaining Uplc-based smart contracts and blockchain applications
Industry UsageUsed in blockchain and decentralized application developmentFocuses on creating and optimizing smart contracts on blockchain platforms

Uplc is a language used for blockchain smart contracts, while a UPLC Developer specializes in developing and deploying these contracts. The roles overlap in blockchain environments but differ in focus: Uplc is the language, and UPLC Developer is the professional implementing it.

More about UPLC jobs
Infographic showing various Uplc job openings in the United States as of August 2026, with employment types broken down into 82% Full Time, 3% Temporary, and 15% Contract. Highlights an 97% Physical, 2% Hybrid, and 1% Remote job distribution, with an average salary of $59,606 per year, or $28.7 per hour.

Scientist II, Formulation Development

Ptc Therapeutics, Inc.

Bridgewater, NJ โ€ข On-site

Full-time

Medical, Dental, Vision, Retirement

Posted 29 days ago


Job description

PTC Therapeutics is a global commercial biopharmaceutical company. For over 25 years our team has been deeply committed to a unified purpose: Extending life's moments for children and adults living with a rare disease.

At PTC, we cultivate an inclusive culture where everyone feels valued, respected, and empowered. We welcome candidates from all backgrounds to join our team, fostering a strong sense of belonging.

Visit our website to learn more about our company and culture!
Site: www.ptcbio.com

Job Description Summary: The Scientist II, Formulation Development actively contributes to drug discovery and drug product development by designing, manufacturing, and characterizing phase-appropriate formulations and process; ensuring a timely supply of formulations or drug product for discovery, preclinical, and clinical studies. This involves performing lab activities, analyzing the data, planning studies and communicating lab results to cross-functional team members and line management, and presenting results to stakeholders as required.
The incumbent works cross-functionally with internal departments and external partners on formulation development related issues.
The Scientist II, Formulation Development supports adherence to relevant regulatory requirements and company Standard Operating Procedures (SOPs) as appropriate.
.Job Description:

ESSENTIAL FUNCTIONS

Primary duties/responsibilities:

  • Designs and develops robust formulations and manufacturing processes for small molecule compounds from drug discovery and/or development programs for preclinical and clinical studies.
  • Prepares experimental designs, evaluates data, coordinates and executes pre-formulation, formulation, and process development studies and identifies pharmaceutical development challenges, and recommends potential solutions.
  • Conducts pre-formulation and formulation studies using various techniques (TGA/DSC, XRPD, PSD, HPLC/UPLC, UPLC/MS, light microscopy, pH, etc.).
  • Works with internal and external partners as necessary to meet formulations needs.
  • Develops safe, viable and robust formulations using pharmaceutically acceptable inactive ingredients that enable the delivery of water insoluble compounds by multiple routes of administration.
  • Conducts formulation and process technology transfers to external partner sites and monitors activities at CDMOs to meet PTC's project timelines.
  • Designs studies and conducts phase-appropriate risk assessments as per target product profiles to build in quality-by-design (QbD) during formulation and process development.
  • Conducts formulation & process scale up and optimization studies using various QbD tools including design of experiments (DoE) and other modeling and scale-up tools.
  • Provides pre-formulation, formulation, and manufacturing support for drug product formulation development; and for the transfer of formulation development to contract manufacturing organizations, as necessary.
  • Independently oversees the maintenance and calibration of laboratory instrumentation within the group (TGA/DSC, XRPD, PSD, HPLC/UPLC, UPLC/MS, light microscopy, pH, etc.).
  • Maintains safe laboratory working conditions and maintains a steady uninterrupted supply of raw materials, reagents, supplies, and any required tools as necessary.
  • Summarizes experimental work in reports, presents the study plans and results to broader teams in a timely manner.
  • Authors the drug product sections of regulatory submissions such as Investigational New Drug applications (INDs), Clinical Trial Applications (CTAs), or their amendments, New Drug Applications (NDAs), Marketing Authorization Applications (MAAs) as necessary.
  • Maintains appropriate experimental records in laboratory notebooks.
  • Mentors and coaches junior team members.
  • Performs other tasks and assignments as needed and specified by management.

KNOWLEDGE/SKILLS/ABILITIES REQUIRED

Minimum level of education and years of relevant work experience:

  • PhD degree in pharmaceutical science, material science, chemistry or other related scientific discipline with minimum 2 years of relevant experience OR Master's degree in these same disciplines with min 4 years of relevant experience OR a Bachelor's degree in these same disciplines and a minimum of 6 years of relevant experience in discovery formulation, pre-formulation or formulation development in a pharmaceutical, biotechnology or other related environment.

Special knowledge or skills needed and/or licenses or certificates required:

  • Hands-on experience and demonstrated proficiency with basic laboratory skills, design, development, and characterization of liquid and solid dosage forms using formulation equipment such as blenders, granulators, roller compactors, tablet presses, coaters, fluid-bed dryers etc.
  • Proven understanding of physical pharmacy & engineering concepts in formulation and process development and related scale-up principles.
  • Proficiency in working with and overseeing CMOs for formulation development and manufacture for PTC projects is desirable.
  • Proficiency with Microsoft Office applications.
  • Excellent verbal and written communication skills.
  • Ability to work independently and collaboratively, as required, in a fast-paced, matrixed, team environment consisting of internal and external team members.
  • Analytical thinker with excellent problem-solving skills and the ability to adapt to changing priorities and deadlines.
  • Excellent planning, organization and time management skills including the ability to support and prioritize multiple projects.

Special knowledge or skills and/or licenses or certificates preferred:

  • Familiarity with the preparation of formulations for drug discovery and clinical support by both oral and parental routes of administration.
  • Understanding of physical chemistry and physical pharmacy as they relate to concepts in preformulation and formulation.
  • Experience using electronic lab notebook.
  • Hands-on experience using and troubleshooting analytical instruments (e.g., High Pressure Liquid Chromatography (HPLC), differential scanning calorimetry (DSC), light microscopy, Karl Fisher (KF), X-ray diffractometer), hot stage microscopy, thermogravimetric analyzer (TGA), etc.
  • Working knowledge of US and international Chemistry, Manufacturing and Control (CMC) regulations and guidance, including Good Manufacturing Practice (GMP), the US Code of Federal Regulations (21CFR) and International Conference of Harmonization (ICH) guidelines is desired.

Travel requirements:

  • 0-10%

Expected Base Salary Range:

  • $133,100- $158,000. The base salary offered will be contingent on assessment of candidate education level, background, and experience relative to the requirements of the position they are being considered for, as well as review of internal equity. In addition to base salary, PTC employees are also eligible for short- and long-term incentives.All eligible employees may also enroll in PTC's medical, dental, vision, and retirement savings plans.

EEO Statement:

PTC Therapeutics is an equal opportunity employer. We welcome applications from all individuals, regardless of race, color, national origin, gender, age, physical characteristics, social origin, disability, religion, family status, pregnancy, sexual orientation, gender identity, gender expression, disability, veteran status or any unlawful criterion under applicable law. We are committed to treating all applicants fairly and avoiding discrimination.

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