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Trial Master File Associate Jobs in Chicago, IL (NOW HIRING)

Associate Attorney (Remote)

Chicago, IL ยท Remote

$100K - $155K/yr

Draft pleadings, motions, written discovery, and other litigation-related filings * Take and defend ... Gain hands-on experience in all phases of litigation through trial and resolution This role is ...

Credit Clerk

Woodridge, IL ยท On-site

$19/hr

Preferred: SAP experience, Associate Degree, credit experience in distribution or manufacturing ... Makes necessary changes to customer's master file requested by Credit Management * Effectively ...

0162 - Associate Attorney

Chicago, IL ยท On-site

$100K - $120K/yr

Manage a caseload of bodily injury litigation files from suit through trial * Draft pleadings, motions, discovery requests/responses, and legal correspondence * Attend court hearings, depositions ...

0162 - Associate Attorney

Chicago, IL ยท On-site

$100K - $120K/yr

Manage a caseload of bodily injury litigation files from suit through trial * Draft pleadings, motions, discovery requests/responses, and legal correspondence * Attend court hearings, depositions ...

Senior Clinical Research Associate

Chicago, IL ยท On-site +1

$110K - $138K/yr

... trial lifecycle. This Sr. CRA role will support the client's Oncology clinical trials to ensure ... Manage site essential document collection and TMF reconciliation with site files * Support sites ...

Associate Manager, Fund Accountant

Chicago, IL ยท On-site

$80K - $125K/yr

Review the daily work prepared by their associates including corporate action processing, pricing downloads, security master file setup, and other data * Proficient with the various software programs ...

Showing results 41-60

Trial Master File Associate information

What are some common challenges Trial Master File Associates face when managing clinical trial documentation?

Trial Master File Associates often encounter challenges such as maintaining completeness and accuracy of documentation, ensuring timely filing of essential documents, and staying updated with evolving regulatory requirements. Managing large volumes of documents across multiple studies and coordinating with cross-functional teams can also be demanding. Effective organization, attention to detail, and strong communication skills are essential to overcome these challenges and ensure compliance with Good Clinical Practice (GCP) guidelines.

What are the key skills and qualifications needed to thrive as a Trial Master File Associate?

To thrive as a Trial Master File (TMF) Associate, you need a solid understanding of clinical research processes, regulatory requirements, and document management, often supported by a degree in life sciences or a related field. Familiarity with electronic TMF (eTMF) systems and knowledge of industry standards like ICH-GCP are typically required. Strong attention to detail, organizational skills, and effective communication help ensure completeness and accuracy in documentation. These skills are crucial for maintaining compliance, supporting clinical trial integrity, and facilitating successful regulatory inspections.

What is the difference between Trial Master File Associate vs Clinical Trial Coordinator?

AspectTrial Master File AssociateClinical Trial Coordinator
CertificationsMay require GCP or regulatory document management certificationsOften requires GCP training, clinical research certifications
Work EnvironmentFocuses on document management within clinical trialsOversees trial operations, patient coordination, site management
Industry UsageCommonly used in pharmaceutical and biotech companiesUsed across clinical research sites and CROs

The Trial Master File Associate primarily manages and maintains essential trial documentation, ensuring compliance and readiness for audits. In contrast, the Clinical Trial Coordinator oversees the overall conduct of clinical trials, including site management and patient coordination. While both roles require knowledge of GCP and clinical research processes, the Associate focuses on document control, whereas the Coordinator handles broader trial operations.

What is a Trial Master File Associate?

A Trial Master File Associate is a clinical research professional responsible for managing and maintaining the Trial Master File (TMF), which is the collection of essential documents for a clinical trial. Their role ensures that all documentation is complete, accurate, and audit-ready throughout the study. TMF Associates support regulatory compliance by organizing, tracking, and archiving documents, often using electronic systems. They work closely with clinical teams and regulatory authorities to facilitate successful trial conduct and inspections.
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Infographic showing various Trial Master File Associate job openings in Chicago, IL as of August 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution.

Associate Attorney (Remote)

Segal McCambridge

Chicago, IL โ€ข Remote

$100K - $155K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 3 days ago


Job description

Segal McCambridge, a nationally recognized litigation firm, is seeking an Associate Attorney to join our General Liability and Complex Litigation team in our Chicago office. This practice handles sophisticated, high-exposure matters involving product liability, catastrophic personal injury, medical malpractice, pharmaceutical and professional negligence, transportation, construction defect, and other complex civil litigation.

This is an outstanding opportunity for attorneys who want meaningful hands-on litigation experience, direct client exposure, and the ability to manage cases while working alongside highly respected trial attorneys in a collaborative, team-oriented environment.

Our associates are given substantial responsibility early and are supported by partners who are deeply committed to mentorship, training, and long-term professional growth.

This is a hybrid position with two in-office days per week.

What You'll Do

As an associate at Segal McCambridge, you will:

  • Manage an active litigation caseload with partner guidance and support
  • Draft pleadings, motions, written discovery, and other litigation-related filings
  • Take and defend depositions, appear in court, and participate in mediations and arbitrations
  • Handle day-to-day case strategy and client communication
  • Work on complex, high-stakes matters for sophisticated national clients
  • Gain hands-on experience in all phases of litigation through trial and resolution

This role is ideal for attorneys seeking increased responsibility, courtroom exposure, and the opportunity to develop as trial lawyers within a highly collaborative litigation team.

What We're Looking For

  • Active license to practice law in Illinois
  • Minimum of 2 years of civil defense litigation experience
  • Strong legal research, writing, motion practice, and advocacy skills
  • Experience handling depositions, discovery, client reporting, and case management responsibilities
  • Ability to manage multiple deadlines and work effectively in a fast-paced environment
  • Strong interpersonal, organizational, and communication skills
  • A proactive mindset and willingness to take ownership of assignments and client matters

Preferred qualifications include:

  • Trial experience
  • Federal court experience
  • Experience handling mediations and arbitrations
  • Dual licensure in another jurisdiction

Why Join Segal McCambridge?

At Segal McCambridge, associates are trusted with meaningful work and given the opportunity to build real litigation experience from day one. You'll work closely with experienced trial attorneys on sophisticated matters while receiving the mentorship and support necessary to grow your practice and advance your career.

We offer:

  • Competitive compensation with bonus opportunities
  • Significant courtroom and litigation experience
  • A collaborative and supportive team culture
  • Clear opportunities for advancement within a growing national firm
  • A flexible hybrid work environment

Compensation & Benefits

Salary range: $100,000 $155,000, commensurate with experience.

In addition to competitive compensation and bonus opportunities, we offer a comprehensive benefits package, including:

  • 401(k) with firm match
  • Health, dental, and vision insurance
  • Health savings and flexible spending accounts
  • Life insurance
  • Paid time off and parental leave
  • Employee assistance program
  • Professional development support
  • Referral bonus program

About Segal McCambridge

Founded in 1986, Segal McCambridge has grown from a four-lawyer firm in Chicago into a nationally recognized litigation firm with offices across the United States. Our attorneys represent Fortune 500 companies, corporations, and individuals in complex litigation matters spanning asbestos, class action, construction, employment, environmental, insurance, life sciences, product liability, professional liability, technology and cyber risk, transportation, warranty, and more.

We are committed to building a culture where talented attorneys are challenged, supported, and given the opportunity to thrive.

If you are looking for sophisticated litigation work, hands-on responsibility, and a firm that values mentorship and professional development, we encourage you to apply and submit your resume.