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Transcriptomics Jobs in Seattle, WA (NOW HIRING)

Uw

Research Scientist/Engineer 3

Seattle, WA

This position is engaged in the field of Spatial transcriptomics and bioinformatics. This position supports the analysis of spatial transcriptomic data generated from kidney biopsy tissue using 10x ...

Vrtx

Director-Head of Molecular Profiling

Seattle, WA · On-site

$203K - $304K/yr

Proven expertise in spatial transcriptomics, CYTOF, single-cell sequencing, and proteomics. * Demonstrated experience in complex data analysis, including the application of AI/ML methods to derive ...

Uw

Research Scientist/Engineer 1

Seattle, WA

$70K/yr

Computational biology/bioinformatics with emphasis on spatial transcriptomics, proteomics, and immunosequencing using Pixelseq and an immune receptorfocused multimodal expansion ("ImmunoPixelseq"

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All JobsTranscriptomics JobsTranscriptomics Jobs in Seattle, WA

Transcriptomics information

See Seattle, WA salary details

$55.8K

$231.6K

$455.2K

How much do transcriptomics jobs pay per year?

As of Jul 15, 2026, the average yearly pay for transcriptomics in Seattle, WA is $231,552.00, according to ZipRecruiter salary data. Most workers in this role earn between $89,300.00 and $455,200.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Transcriptomics Scientist, and why are they important?

To thrive as a Transcriptomics Scientist, you need a strong background in molecular biology, genomics, and bioinformatics, typically supported by an advanced degree in a relevant field. Familiarity with next-generation sequencing (NGS) platforms, RNA-seq analysis pipelines, and programming languages like R or Python is essential. Attention to detail, problem-solving abilities, and effective communication skills set outstanding candidates apart. These competencies are vital for generating accurate transcriptomic data, interpreting complex results, and collaborating within multidisciplinary research teams.

What does transcriptomics do?

Transcriptomics is a field within molecular biology that studies the complete set of RNA transcripts produced by a genome under specific conditions. Professionals in this area analyze gene expression patterns using tools like RNA sequencing to understand cellular functions and disease mechanisms.

What biology jobs pay over $100k?

In the field of transcriptomics, roles such as senior research scientist, bioinformatics director, and molecular biology manager often have salaries exceeding $100,000 annually. These positions typically require advanced degrees, extensive experience, and skills in data analysis, programming, and laboratory techniques.

What is transcriptomics?

Transcriptomics is the study of the complete set of RNA transcripts produced by the genome under specific circumstances or in a specific cell. It provides insights into gene expression patterns, how genes are regulated, and how cells respond to various conditions. By analyzing the transcriptome, researchers can better understand biological processes, disease mechanisms, and identify potential targets for therapy. Technologies such as RNA sequencing (RNA-seq) are commonly used in transcriptomics research.

What are some common challenges faced by professionals working in transcriptomics, and how can they be addressed?

Professionals in transcriptomics frequently encounter challenges such as handling large and complex datasets, ensuring data quality, and staying current with rapidly evolving analytical tools and technologies. Working closely with bioinformaticians and statisticians is essential for effective data analysis and interpretation. Additionally, clear communication and collaboration with wet-lab biologists and clinicians help bridge the gap between raw data and meaningful biological insights. Regular training and professional development can help transcriptomics professionals stay updated with the latest best practices and software advancements.

What is the highest paying job in genetics?

In genetics, roles such as genetic counselors, research directors, and senior clinical geneticists tend to have the highest salaries, often exceeding six figures annually. Positions requiring advanced degrees, specialized skills, and leadership responsibilities typically offer the highest compensation in the field.

What is the highest paying job in bioinformatics?

In bioinformatics, senior roles such as bioinformatics directors, principal scientists, or lead data scientists tend to have the highest salaries, often exceeding $150,000 annually. These positions typically require advanced skills in programming, data analysis, and experience with large-scale genomic or transcriptomic data, along with leadership responsibilities.

What is the difference between Transcriptomics vs Bioinformatics?

AspectTranscriptomicsBioinformatics
Required credentialsBachelor's or Master's in Biology, Genetics, or related fields; experience with sequencing technologiesBachelor's or Master's in Computer Science, Bioinformatics, or related fields; programming skills
Work environmentLaboratories, research institutions, biotech companiesResearch labs, biotech firms, academic institutions, data analysis centers
Industry usageGenomics, molecular biology, medical researchData analysis, software development, computational biology

While both Transcriptomics and Bioinformatics involve analyzing biological data, Transcriptomics focuses on studying gene expression profiles using sequencing technologies, whereas Bioinformatics encompasses a broader range of computational methods to analyze various biological datasets. Professionals in both fields often collaborate but have distinct skill sets and work environments.

What are popular job titles related to Transcriptomics jobs in Seattle, WA? For Transcriptomics jobs in Seattle, WA, the most frequently searched job titles are:
What job categories do people searching Transcriptomics jobs in Seattle, WA look for? The top searched job categories for Transcriptomics jobs in Seattle, WA are:
Transcriptomics jobs near you
Immunology Senior Research Scientist - Spatial Transcriptomics

Immunology Senior Research Scientist - Spatial Transcriptomics

Vertex Pharmaceuticals

Seattle, WA • On-site

$124K - $186K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 9 days ago

Job description

Job Description
At Vertex, we invest in scientific innovation to create transformative medicines for people with serious diseases. Our growing Molecular Profiling team is seeking a Senior Scientist, Spatial Transcriptomics to provide scientific and deep technical expertise in spatial biology to support discovery, translational, and development programs. This role will be instrumental in driving mechanistic insights into disease biology, tissue microenvironments, and therapeutic response through spatial profiling of gene expression in tissue context.
The ideal candidate will bring deep expertise in spatial transcriptomics, tissue-based molecular profiling, experimental design, and data interpretation, along with strong cross-functional collaboration skills and a passion for technical innovation.
Key Duties and Responsibilities:
  • Lead the design, execution, and optimization of spatial transcriptomics studies to address key biological questions in disease-relevant tissues and model systems
  • Lead efforts to characterize tissue architecture, cellular microenvironments, cell-cell interactions, and spatial organization of biological processes
  • Generate and interpret high-quality spatial data to derive biological insights that support disease biology, target biology, mechanism of action, and biomarker strategies
  • Integrate spatial transcriptomics data with complementary datasets, including single-cell RNA-seq, proteomics, imaging, histology, and other molecular profiling approaches to enable multi-modal biological insights
  • Develop, validate, and implement robust workflows for sample preparation, assay execution, quality control, and data review
  • Evaluate and apply emerging spatial biology technologies to expand research capabilities and enable innovative scientific applications
  • Drive adoption of best practices and contribute to establishing robust spatial biology workflows and standards across the team
  • Partner closely with cross-functional teams across disease biology, pharmacology, translational medicine, biomarker sciences, bioinformatics, and clinical development to inform study design, data interpretation, and program strategy
  • Contribute to internal scientific strategy through clear communication of results, technical recommendations, and experimental insights
  • Prepare technical documentation, protocols, study summaries, and presentations
  • Mentor junior scientists and help build a collaborative, high-performing team environment

Knowledge and Skills:
  • Deep expertise in spatial transcriptomics and tissue-based molecular profiling
  • Strong understanding of transcriptomics, RNA biology, tissue architecture, and cellular heterogeneity
  • Experience with fresh frozen and FFPE tissue processing, tissue quality assessment, and assay optimization
  • Familiarity with one or more spatial biology platforms, including sequencing-based and imaging-based technologies
  • Experience integrating spatial data with single-cell, proteomic, imaging, and histologic datasets
  • Working knowledge of computational approaches for spatial data analysis, visualization, and interpretation, including proficiency in R and/or Python and familiarity with relevant analysis tools and workflows
  • Strong experimental rigor, problem-solving ability, and attention to data quality and reproducibility
  • Excellent communication skills and ability to work effectively in a matrixed, multidisciplinary environment

Education and Experience:
  • PhD in Immunology, Cell Biology, Molecular Biology, Biology, Biomedical Sciences, or related discipline with 2+ years of relevant experience; or
  • Master's degree with 6+ years of relevant experience; or
  • Bachelor's degree with 8+ years of relevant experience

Preferred Qualifications:
  • Hands-on experience with one or more spatial transcriptomics platforms (e.g., sequencing-based or imaging-based such as 10x Genomics Visium, Nanostring CosMx or similar technologies)
  • Experience with histology, immunofluorescence, image analysis, and multiplexed tissue profiling
  • Experience supporting drug discovery, translational research, or clinical biomarker development, ideally in immunology or inflammation
  • Familiarity with single-cell RNA-seq analysis and integration of multi-omics datasets
  • Experience in immunology and inflammation disease areas
  • Knowledge of spatial proteomics or broader tissue-based profiling approaches

Pay Range:
$124,200 - $186,400
Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation:
On-Site Designated
Flex Eligibility Status:
In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.
#LI-Onsite
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

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