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Transcriptomics Jobs in Tennessee (NOW HIRING)

Vanderbilt University

Staff Scientist

Nashville, TN · On-site

By integrating single-cell and spatial transcriptomics, CRISPR genome engineering, tissue clearing, advanced microscopy, and functional studies in zebrafish and mouse models, we seek to identify ...

Vanderbilt University

Research Assistant

Nashville, TN · On-site

$18.50 - $25.50/hr

We deploy frontline genetics, transcriptomics, epigenomics, in vivo cellular, molecular, and behavioral approaches in zebrafish and mouse models to uncover innate mechanisms of spinal cord ...

ORAU

Research Associate 2

Oak Ridge, TN · On-site +1

$35.19 - $48.95/hr

... transcriptomics, proteomics, metabolomics) and biological entities (e.g., cell, connectivity, tissue, drug, organ). * Regular engagement and meetings with selected mentor to ensure guidance on ...

ORAU

Research Associate 2

Oak Ridge, TN · On-site +1

$35.19 - $48.95/hr

... transcriptomics, proteomics, metabolomics) and biological entities (e.g., cell, connectivity, tissue, drug, organ). * Regular engagement and meetings with selected mentor to ensure guidance on ...

ORAU

Research Associate 2

Oak Ridge, TN · On-site +1

$35.19 - $48.95/hr

... transcriptomics, proteomics, metabolomics) and biological entities (e.g., cell, connectivity, tissue, drug, organ). * Regular engagement and meetings with selected mentor to ensure guidance on ...

All JobsTranscriptomics JobsTranscriptomics Jobs in Tennessee

Transcriptomics information

What are the key skills and qualifications needed to thrive as a transcriptomics scientist, and why are they important?

To thrive as a Transcriptomics Scientist, you need a strong background in molecular biology, genomics, and bioinformatics, typically supported by an advanced degree in a relevant field. Familiarity with next-generation sequencing (NGS) platforms, RNA-seq analysis pipelines, and programming languages like R or Python is essential. Attention to detail, problem-solving abilities, and effective communication skills set outstanding candidates apart. These competencies are vital for generating accurate transcriptomic data, interpreting complex results, and collaborating within multidisciplinary research teams.

What is transcriptomics?

Transcriptomics is the study of the complete set of RNA transcripts produced by the genome under specific circumstances or in a specific cell. It provides insights into gene expression patterns, how genes are regulated, and how cells respond to various conditions. By analyzing the transcriptome, researchers can better understand biological processes, disease mechanisms, and identify potential targets for therapy. Technologies such as RNA sequencing (RNA-seq) are commonly used in transcriptomics research.

What are some common challenges faced by professionals working in transcriptomics, and how can they be addressed?

Professionals in transcriptomics frequently encounter challenges such as handling large and complex datasets, ensuring data quality, and staying current with rapidly evolving analytical tools and technologies. Working closely with bioinformaticians and statisticians is essential for effective data analysis and interpretation. Additionally, clear communication and collaboration with wet-lab biologists and clinicians help bridge the gap between raw data and meaningful biological insights. Regular training and professional development can help transcriptomics professionals stay updated with the latest best practices and software advancements.

What is the difference between Transcriptomics vs Bioinformatics?

AspectTranscriptomicsBioinformatics
Required credentialsBachelor's or Master's in Biology, Genetics, or related fields; experience with sequencing technologiesBachelor's or Master's in Computer Science, Bioinformatics, or related fields; programming skills
Work environmentLaboratories, research institutions, biotech companiesResearch labs, biotech firms, academic institutions, data analysis centers
Industry usageGenomics, molecular biology, medical researchData analysis, software development, computational biology

While both Transcriptomics and Bioinformatics involve analyzing biological data, Transcriptomics focuses on studying gene expression profiles using sequencing technologies, whereas Bioinformatics encompasses a broader range of computational methods to analyze various biological datasets. Professionals in both fields often collaborate but have distinct skill sets and work environments.

What are popular job titles related to Transcriptomics jobs in Tennessee? For Transcriptomics jobs in Tennessee, the most frequently searched job titles are:
What job categories do people searching Transcriptomics jobs in Tennessee look for? The top searched job categories for Transcriptomics jobs in Tennessee are:
What cities in Tennessee are hiring for Transcriptomics jobs? Cities in Tennessee with the most Transcriptomics job openings:
Transcriptomics jobs near you
Infographic showing various Transcriptomics job openings in Tennessee as of August 2026, with employment types broken down into 100% Full Time. Highlights an 89% In-person, and 11% Hybrid job distribution.

Scientist/Sr Scientist- Immunology

St. Jude Children's Research Hospital

Memphis, TN • On-site

Full-time

Posted 12 days ago

St. Jude Children's Research Hospital rating

8.6

Company rating: 8.6 out of 10

Based on 12 frontline employees who took The Breakroom Quiz

40th of 1,055 rated hospitals

Job description

The World's Brightest Minds Always Innovate
At St. Jude Children's Research Hospital, we know what can be achieved when the brightest scientific minds face the fewest barriers. That's why we provide world-class facilities. State-of-the-art technologies. Extraordinary support. And a collaborative, bench-to-bedside environment where you can see, firsthand, how your science translates into survival for the children we serve. Quite simply, at St. Jude, we encourage you to dream big and stop at nothing when it comes to finding cures and saving children.
We are seeking a highly collaborative Scientist or Sr. Scientist in spatial metabolomics and immunophenotyping to join the Department of Immunology, St. Jude Children's Research Hospital. The successful candidate will oversee the day-to-day operations, instrument maintenance, method development, and user training for cutting-edge MALDI mass spectrometry imaging (MSI) platform. This role is uniquely positioned at the intersection of immunology, metabolism, and spatial biology. The primary responsibility centers on optimizing MALDI-MSI tissue workflows, including instrument purchase and management, method development, sample preparation, data acquisition, and data analysis.
Additionally, the scientist will also play a pivotal role in collaborating with other cores and shared resources to integrate spatial metabolomics datasets with high-dimensional data acquired from additional platforms such as spatial transcriptomics and proteomics (multi-omics) platforms. As a key technical consultant for collaborations with principal investigators and/or lab personnel, the scientist will help them design well-powered spatial immunology experiments and provide support for grant and paper preparations.
The ideal candidate should have extensive hands-on experience in operating and troubleshooting MSI instrumentation, familiarity with MSI data analysis, computational methodologies and integrative analysis of MSI and other high-dimensional datasets (e.g., spatial transcriptomics and multiplexed antibody imaging), and a strong understanding of immune or cancer metabolism, particularly in tissue-specific contexts.
As the scientific lead for the spatial metabolomics platform, you will:
  • Develop, execute, and oversee specialized methods for mapping metabolites, lipids, proteins/peptides, and other small molecules in diverse immune and tumor microenvironments.
  • Oversee daily operations, calibration, optimization, and routine maintenance of core MALDI/DESI imaging mass spectrometers.
  • Analyze complex spatial metabolomics and related datasets, integrate them with multi-omics datasets (e.g., spatial transcriptomics and multiplexed antibody imaging) as needed, and interpret tissue features and biological insights.
  • Coordinate multiple aspects of research projects and execute laboratory experiments utilizing appropriate laboratory techniques, tools, and methods.
  • Provide inputs regarding research protocols and experiments, set up protocols, and assist in developing new laboratory techniques as required.
  • Identify, process, organize, summarize, review, and report relevant experimental data.
  • Draft sections of research manuscripts and grants as directed.
  • Support monitoring and stocking of supplies, and calibration, maintenance, troubleshooting, and purchase of equipment within the area. Instruct other staff in basic laboratory techniques and procedures.
  • Design, troubleshoot, and refine experimental approaches to answer critical research questions.
  • Process, organize, and analyze complex datasets, providing detailed reports on findings
  • Provide technical support for ongoing projects, including maintaining datasets, lab documentation, and compliance with safety regulations.
  • Engage in collaborative research projects with internal and external teams to advance research and translation in immunology.

Minimum Education:
  • Bachelor's degree in relevant scientific area is required

Senior Scientist Minimum Experience:
  • Ten (10) years relevant work experience is required
  • Eight (8) years of relevant work experience is required with a Master's degree
  • Five (5) years of relevant work experience is required with a PhD

Scientist Minimum Experience:
  • Eight (8) years of relevant work experience is required
  • Six (6) years of relevant work experience is required with a Master's degree
  • Three (3) years of relevant work experience is required with a PhD

Compensation
In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $104,000 - $186,160 per year for the role of Scientist/Sr Scientist- Immunology.
Explore our exceptional benefits!
St. Jude is an Equal Opportunity Employer
No Search Firms
St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

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