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Postdoctoral Associate in Developmental Neurobiology and Neural Circuit Regeneration (University of Pittsburgh)

The Department of Neurobiology at the University of Pittsburgh School of Medicine invites applications for a highly motivated Postdoctoral candidate to join the laboratory of Dr. Vibhu Sahni. The laboratory investigates the molecular and developmental mechanisms that establish long-range corticofugal connectivity and determine developmental processes that contribute to the regenerative failure of this circuit. Using mouse genetic models, viral tools, molecular profiling, and anatomical and functional analyses, the laboratory seeks to define how developmental programs shape neural circuit assembly and identify strategies to restore axon growth and functional recovery following injury.

The successful candidate will develop an independent research program while contributing to ongoing laboratory projects investigating the development and regeneration of descending motor pathways. Current research focuses on understanding how developmental gene regulatory programs control the formation of cortical projections to the brainstem and spinal cord, how these programs contribute to the developmental loss of axon regenerative capacity, and how these mechanisms can be manipulated to promote regeneration after injury.

The candidate will employ a combination of molecular biology, mouse genetics, viral gene delivery, histology, microscopy, neural circuit tracing, and computational analysis. Additional responsibilities include mentoring graduate and undergraduate trainees, participating in laboratory management, presenting research at national and international meetings, and contributing to manuscript and grant preparation. The successful applicant will join a vibrant neuroscience community at the University of Pittsburgh with extensive opportunities for collaboration across the Department of Neurobiology, the Center for Neuroscience, and affiliated research centers.

Applicants must have a Ph.D. in Neuroscience, Developmental Biology, Molecular Biology, Biomedical Engineering, or a closely related field. Experience in one or more of the following areas is desirable: developmental neuroscience, neural regeneration, mouse genetics, molecular biology, viral vector approaches, imaging, neuroanatomy, transcriptomics, or computational analysis of biological data. Strong written and verbal communication skills, a demonstrated publication record, and the ability to work both independently and collaboratively are expected.

Interested candidates should attach a brief statement of research interests and CV to requisition #26004639.