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Toxicology Data Science Jobs (NOW HIRING)

Interpret toxicology data and communicate results to program teams and senior management. * Write ... Lead issue-resolution teams, driving the science for investigative and discovery toxicology as ...

The Computational Toxicology Group within Nonclinical Drug Safety (NDS) seeks a senior AI/ML ... Computational Biology, Computational Chemistry, Data Engineering, Data Modeling, Data Science, Data ...

The Computational Toxicology Group within Nonclinical Drug Safety (NDS) seeks a senior AI/ML ... Computational Biology, Computational Chemistry, Data Engineering, Data Modeling, Data Science, Data ...

Oversee GLP and non-GLP toxicology and safety pharmacology studies at CROs, ensure scientific rigor, data integrity, and regulatory compliance (GLP, animal welfare, and safety), SOPs, and technical ...

Oversee GLP and non-GLP toxicology and safety pharmacology studies at CROs, ensure scientific rigor, data integrity, and regulatory compliance (GLP, animal welfare, and safety), SOPs, and technical ...

... data in the context of regulatory expectations. * Oversee and manage multiple contract research organizations (CROs) supporting outsourced toxicology studies, ensuring scientific quality, adherence ...

The department is composed of highly collaborative scientists and offers a supportive environment ... Experience generating, integrating, reviewing, and interpreting toxicology data * Experience ...

... data in the context of regulatory expectations. * Oversee and manage multiple contract research organizations (CROs) supporting outsourced toxicology studies, ensuring scientific quality, adherence ...

Manager NA-Toxicology Location: North America, United States, New Jersey, Summit Work Location: Hybrid What you will do In this role, you will leverage advanced computational, omics, and data science ...

Manager NA-Toxicology Location: North America, United States, New Jersey, Summit Work Location: Hybrid What you will do In this role, you will leverage advanced computational, omics, and data science ...

Manager NA-Toxicology Location: North America, United States, New Jersey, Summit Work Location: Hybrid What you will do In this role, you will leverage advanced computational, omics, and data science ...

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Toxicology Data Science information

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How much do toxicology data science jobs pay per year?

As of Jun 18, 2026, the average yearly pay for toxicology data science in the United States is $142,460.00, according to ZipRecruiter salary data. Most workers in this role earn between $118,500.00 and $166,500.00 per year, depending on experience, location, and employer.
Infographic showing various Toxicology Data Science job openings in the United States as of June 2026, with employment types broken down into 69% Full Time, 23% Part Time, and 8% Contract. Highlights an 88% Physical, 3% Hybrid, and 9% Remote job distribution, with an average salary of $142,460 per year, or $68.5 per hour.
Principal Scientist, Toxicology

Principal Scientist, Toxicology

Dyne Therapeutics

Waltham, MA • On-site

Other

Posted 28 days ago


Job description

Role Summary:

The Principal Scientist, Toxicology is a key member of preclinical development teams and is responsible for the strategic planning and execution of nonclinical safety plans for Dyne's portfolio programs, supporting late discovery through first-in-human and proof-of-concept clinical studies of investigational antibody oligonucleotide therapeutics to treat serious muscle diseases. The role applies an in-depth understanding of regulatory guidance related to nonclinical development and designs, oversees, and critically evaluates exploratory and GLP-compliant toxicology studies. The Principal Scientist authors and reviews nonclinical regulatory documents and participates in interactions with regulatory authorities.

This is a full-time position based in Waltham, MA


Primary Responsibilities:

  • Represent toxicology on program teams, providing expertise and guidance from discovery through development.
  • Design and execute nonclinical safety plans for Dyne candidate therapeutics.
  • Serve as the principal contact to external CROs executing these studies, ensuring studies are conducted in line with the appropriate quality and regulatory standards and guidelines (FDA, CHMP, WHO and GLP).
  • Interpret toxicology data and communicate results to program teams and senior management.
  • Write submission-ready documentation and appropriate toxicology content of regulatory submissions.
  • Lead issue-resolution teams, driving the science for investigative and discovery toxicology as needed.

Education and Skills Requirements:

  • PhD or equivalent experience in a scientific discipline and a minimum of 8+ years related experience.
  • Relevant board certification preferred.
  • Demonstrated expertise in nonclinical safety assessment and the ability to provide scientific leadership across development programs.
  • Experience designing, managing, and overseeing nonclinical toxicology studies, including work conducted at contract research organizations.
  • Strong understanding of regulatory requirements governing nonclinical safety, with experience ensuring compliant study execution and documentation.
  • Proven ability to interpret and critically evaluate toxicology data and author or review high-quality study reports and regulatory documentation.
  • Ability to anticipate, assess, and address nonclinical safety and regulatory risks in complex development environments.
  • Experience applying or advancing toxicological methods, technologies, or approaches.
  • Experience assessing toxicity of antibody-drug conjugates and or oligonucleotide-based therapeutics is a plus.
  • Expertise in immunology or immunotoxicology is a plus.
  • Excellent written and verbal communication skills, with the ability to communicate complex scientific concepts to cross-functional stakeholders.
  • Demonstrated ability to work effectively in a collaborative, fast-paced environment while managing multiple priorities and timelines.

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