Technical Operations Scientist Jobs in Madison, WI

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Let’s do this! Let’s change the world!

In this vital role you will be responsible for developing, maintaining, and deploying first principles and/or machine learning models for biopharmaceutical processes, including but not limited to, cell culture, biologics formulation development, and fill/finish processes. You will be responsible for model design, selection of underlying technologies and infrastructure, and ensuring successful application of models in Process Development.

The ideal candidate will have a strong background in chemical engineering or mechanical engineering as well as expertise in data science to tackle challenging cross‑functional projects. Fundamental understanding of bioprocesses as well as first principles (i.e., transport phenomena, fluid mechanics, reaction kinetics) is preferred. The candidate will be part of cross-functional project teams with frequent interactions with Amgen’s SMEs and stakeholders as well as document and communicate the underlying technical basis of the models for use by engineers and scientists.

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  Design, develop, and deploy first principles, machine learning, and hybrid models to optimize biopharmaceutical processes.

  
  
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  Integrate modeling software with connectivity to real‑time equipment data to enable digital twins for improved process performance and understanding.

  
  
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  Build and maintain robust data pipelines and agentic workflows to streamline the effort required to generate impact‑level insights.

  
  
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  Collaborate with cross‑functional teams to translate scientific challenges into data‑driven solutions and ensure seamless model integration into process development workflows.

  
  
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  Champion best practices in software development, including version control, testing, and continuous integration to ensure model reliability, scalability, and reproducibility.

  
  

We are all different, yet we all use our unique contributions to serve patients. The Data Sciences professional we seek is an individual with these qualifications.

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  High school diploma / GED and 10 years of Data Sciences experience OR

  
  
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  Associate’s degree and 8 years of Data Sciences experience OR

  
  
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  Bachelor’s degree and 4 years of Data Sciences experience OR

  
  
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  Master’s degree and 2 years of Data Sciences experience OR

  
  
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  Doctorate degree

  
  

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  Ph.D. in Chemical Engineering, Mechanical Engineering, Applied Math, or related field

  
  
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  Strong background in mechanistic modeling and first principles (e.g., transport phenomena, fluid mechanics, reaction kinetics)

  
  
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  Experience in applying AI and ML algorithms to produce data‑driven solutions to engineering problems

  
  
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  Track record of leading modeling and data science projects

  
  
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  3+ yrs of coding experience in Python

  
  
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  Understanding of biopharmaceuticals process and related unit operations

  
  
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  Experience using Git for version control

  
  
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  Familiarity with DevOps and software best practices (i.e., version control, continuous integration, test driven development)

  
  
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  Experience with data engineering & visualization tools (e.g., Databricks, Spotfire) as well as cloud computing and data storage systems such as AWS

  
  
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  Experience leveraging AI tools to generate agentic solutions for scientific workflows

  
  
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  Independent, self‑motivated, organized, and able to multi‑task in time‑sensitive environments

  
  
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  Excellent communication skills (written and verbal)

  
  
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  Strong analytical skills with the ability to collect, organize, analyze, and disseminate significant amounts of information with attention to detail and accuracy

  
  

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well‑being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

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  A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts

  
  
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  A discretionary annual bonus program, or for field sales representatives, a sales‑based incentive plan

  
  
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  Stock‑based long‑term incentives

  
  
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  Award‑winning time‑off plans

  
  
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  Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

  
  

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.