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System Engineering Jobs in Pennsylvania (NOW HIRING)

System One

Lead System Engineer

Pittsburgh, PA · On-site

The position will contribute to system optimization, performance validation, and operational ... Collaborate with scientific and engineering teams to align device design with experimental ...

System One

Lead System Engineer

Pittsburgh, PA · On-site

The position will contribute to system optimization, performance validation, and operational ... Collaborate with scientific and engineering teams to align device design with experimental ...

System One

Lead System Engineer

Pittsburgh, PA · On-site

The position will contribute to system optimization, performance validation, and operational ... Collaborate with scientific and engineering teams to align device design with experimental ...

System One

Lead System Engineer

Pittsburgh, PA · On-site

The position will contribute to system optimization, performance validation, and operational ... Collaborate with scientific and engineering teams to align device design with experimental ...

System One

Lead System Engineer

Pittsburgh, PA · On-site

The position will contribute to system optimization, performance validation, and operational ... Collaborate with scientific and engineering teams to align device design with experimental ...

NDI Engineering

Senior Systems Engineer

Philadelphia, PA · On-site

$95K - $130K/yr

Position involves using digital models to manage and integrate system engineering activities, ensuring traceability, compliance, and performance across the product lifecycle and blends systems ...

Lockheed Martin

Systems Engineer

King Of Prussia, PA · Hybrid

As an Engineering Professional on the TTWCS program, you will perform system engineering efforts leading change packages to the existing software system, performing requirements development ...

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Showing results 21-40

All JobsSystem Engineering JobsSystem Engineering Jobs in Pennsylvania

System Engineering information

See Pennsylvania salary details

$53.6K

$127.5K

$167.4K

How much do system engineering jobs pay per year?

As of Aug 18, 2026, the average yearly pay for system engineering in Pennsylvania is $127,520.00, according to ZipRecruiter salary data. Most workers in this role earn between $98,200.00 and $157,400.00 per year, depending on experience, location, and employer.

What is system engineering?

System engineering is an interdisciplinary field that focuses on designing, integrating, and managing complex systems throughout their life cycles. It involves understanding and defining customer needs, translating them into system requirements, and creating solutions that span hardware, software, and processes. System engineers coordinate across various disciplines, ensuring that all parts of a project work together efficiently and effectively. Their work is crucial in industries such as aerospace, defense, IT, and manufacturing.

What are the key skills and qualifications needed to thrive as a system engineer?

To thrive as a System Engineer, you need a solid background in computer science or engineering, along with expertise in systems architecture, troubleshooting, and integration. Familiarity with operating systems (like Linux and Windows), scripting languages, cloud platforms, and certifications such as CompTIA, AWS, or Microsoft Certified: Azure are commonly required. Strong problem-solving abilities, communication, and collaboration skills help system engineers excel in cross-functional teams and resolve complex technical challenges. These skills and qualities are vital to ensure reliable, scalable, and secure IT infrastructure that meets organizational needs.

What are some common challenges faced by system engineers when working on cross-functional teams?

System Engineers often collaborate with professionals from software development, hardware design, quality assurance, and project management. A common challenge is ensuring clear communication across these teams, as each may use different technical jargon and have distinct priorities. System Engineers must bridge these gaps, translating requirements and constraints to all stakeholders while balancing technical feasibility with project timelines. Developing strong interpersonal skills and a proactive approach to problem-solving can help overcome these challenges and lead to successful project outcomes.

What is the difference between System Engineering vs Network Engineering?

AspectSystem EngineeringNetwork Engineering
Required CredentialsBachelor's in Engineering, certifications like INCOSE, PMPBachelor's in Computer Science or related, Cisco certifications (CCNA, CCNP)
Work EnvironmentDesigning and integrating complex systems across industriesDesigning, implementing, and maintaining computer networks
Employer & Industry UsageManufacturing, aerospace, defense, ITTelecommunications, IT services, enterprise networks
Common Search & ComparisonOften compared for technical scope and certificationsFocuses on network infrastructure and security

System Engineering and Network Engineering share overlapping skills in technical certifications and work environments, but differ in focus. System Engineers design complex systems across various industries, while Network Engineers specialize in network infrastructure. Both roles are vital in technology and engineering sectors, often requiring similar credentials but serving distinct functions.

Is a system engineering a high paying job?

System engineering is generally considered a well-paying profession, especially for those with specialized skills, certifications, and experience in areas like systems design, integration, and project management. Salaries can vary based on industry, location, and level of expertise, but it is often among the higher-paying engineering roles.

What is the job of a system engineer?

A system engineer designs, develops, and manages complex systems, ensuring they operate efficiently and meet requirements. They analyze system needs, integrate hardware and software components, and often use tools like modeling and simulation. Strong problem-solving skills and knowledge of engineering principles are essential for this role.

What jobs can you get as a system engineer?

A system engineer can work in roles such as systems analyst, network engineer, security engineer, or infrastructure engineer. These positions involve designing, implementing, and maintaining complex IT systems, often requiring knowledge of networking, scripting, and certifications like CompTIA or Cisco. Job opportunities are available across industries including technology, defense, healthcare, and manufacturing.
System Engineering jobs near you
Infographic showing various System Engineering job openings in Pennsylvania as of August 2026, with employment types broken down into 1% As Needed, 79% Full Time, 18% Part Time, and 2% Contract. Highlights an 91% Physical, 3% Hybrid, and 6% Remote job distribution, with an average salary of $127,520 per year, or $61.3 per hour.

Lead System Engineer

System One

Pittsburgh, PA • On-site

Full-time

Re-posted 28 days ago

Job description

Title: Lead Design Engineer Location: Onsite, Pittsburgh, PA 15213 Type: Direct-Hire/Permanent Hours: Standard business hours Start: May Overview: Join a cutting-edge lab to discover novel therapeutics that are seeking a highly motivated Lead Engineer to support the development, integration, and operation of advanced aerosol delivery, sensing, and exposure systems for human-relevant experimental platforms. This role focuses on ensuring precise, reproducible generation and delivery of airborne agents, as well as integration of instrumentation and multi-system platforms to enable controlled and standardized experimental workflows. The position will contribute to system optimization, performance validation, and operational readiness in complex laboratory environments. Responsibilities:

  • Design, prototype, and refine biomedical devices and components supporting advanced experimental system
  • Develop and optimize fabrication processes to ensure consistency, quality, and scalability
  • Contribute to selection and evaluation of materials, fabrication methods, and assembly workflows
  • Perform testing and validation of device performance, including durability, reproducibility, and functional integrity
  • Collaborate with scientific and engineering teams to align device design with experimental requirements
  • Maintain documentation related to design iterations, fabrication processes, and quality control
  • Troubleshoot device-related issues and implement design improvements
  • Support coordination of engineering activities across multidisciplinary teams and contribute to project execution
  • Contribute to preparation of technical documentation, reports, and related materials

Requirements:

  • Bachelor’s degree in Biomedical Engineering, Mechanical Engineering, Electrical / System Engineering, or a related field
  • Minimum of 3 years of relevant experience in device design, prototyping, or fabrication
  • Experience with engineering design tools (e.g., CAD software)
  • Strong problem-solving skills and attention to detail
  • Ability to work effectively in multidisciplinary research and engineering environments

Preferred Qualifications

  • Master’s or Ph.D. in a relevant engineering discipline
  • Experience with fabrication of small-scale or precision-engineered devices, including Organs-on-Chips, injection molding, and CNC milling
  • Familiarity with polymer-based materials and manufacturing processes
  • Experience with iterative prototyping and design-for-manufacturing principles
  • Experience working at the interface of engineering and biological systems

#M3 #LI-DS2 Ref: #558-Scientific