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Synthesis Jobs in California (NOW HIRING)

Tacit

RF Frequency Synthesis Architect

San Francisco, CA · On-site

$150K - $200K/yr

About the role We are seeking an RF Frequency Synthesis Architect to design and advance our next generation RF signal synthesis architectures. The ideal candidate has strong expertise in PLLs ...

Cadence

Software Engineer II , Synthesis

San Jose, CA · On-site

$101K - $188K/yr

Genus is a comprehensive tool suite for logic synthesis and physical design, offering broad functionality that drives technology leadership in the electronic design automation (EDA) space. As a ...

Cadence

Software Engineer II , Synthesis

San Jose, CA · On-site

Cadence Design Systems is seeking a highly motivated software engineer to join their Research & Development staff for the Genus Synthesis Solution product. The role involves designing, developing ...

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All JobsSynthesis JobsSynthesis Jobs in California

Synthesis information

See California salary details

$93.8K

$139.6K

How much do synthesis jobs pay per year?

As of Jul 21, 2026, the average yearly pay for synthesis in California is $137,583.00, according to ZipRecruiter salary data. Most workers in this role earn between $134,200.00 and $138,200.00 per year, depending on experience, location, and employer.

What is the difference between Synthesis vs Chemist?

AspectSynthesisChemist
Required CredentialsTypically a degree in chemistry or related field; specialized training in synthesis techniquesDegree in chemistry; broader focus including analysis, testing, and research
Work EnvironmentLaboratories, manufacturing plants, R&D facilitiesLaboratories, research institutions, industry settings
Employer & Industry UsagePharmaceutical, chemical manufacturing, biotechPharmaceutical, chemical, academic, industrial research
Common Search & ComparisonYesYes

While both Synthesis and Chemist roles involve working in chemistry-related environments, Synthesis specialists focus primarily on creating chemical compounds through specific processes. Chemists have a broader scope, including analysis, testing, and research. Understanding these differences helps clarify career paths and job expectations in the chemical industry.

What are synthesis jobs?

Synthesis jobs typically involve the creation or combination of materials, ideas, or data to produce new compounds, products, or insights. In scientific fields, especially chemistry, synthesis refers to constructing complex chemical compounds from simpler substances. In other contexts, such as research or data analysis, it can mean integrating information from multiple sources to generate new understanding. Synthesis roles require analytical thinking, attention to detail, and often specialized technical knowledge. These jobs are found in industries such as pharmaceuticals, materials science, and academic research.

How does a Synthesis professional typically collaborate with cross-functional teams during a project?

Synthesis professionals often serve as a bridge between research, development, and engineering teams, ensuring that insights and data are translated into actionable solutions. They work closely with scientists to understand research findings, partner with engineers to implement processes, and communicate progress to project managers. This collaborative environment requires strong communication skills and adaptability, as priorities can shift based on project needs. Being proactive in facilitating discussions and documenting outcomes also helps maintain alignment across all stakeholders.

What are the key skills and qualifications needed to thrive as a Synthesis Chemist, and why are they important?

To thrive as a Synthesis Chemist, you need a strong background in organic and inorganic chemistry, analytical techniques, and typically a bachelor's or advanced degree in chemistry or a related field. Familiarity with laboratory instrumentation such as NMR, HPLC, GC-MS, and adherence to safety protocols are essential, along with experience using lab management software. Attention to detail, problem-solving abilities, and effective communication set outstanding synthesis chemists apart. These skills are crucial to ensure precise compound creation, maintain lab safety, and collaborate efficiently within research and development teams.
What are popular job titles related to Synthesis jobs in California? For Synthesis jobs in California, the most frequently searched job titles are:
What job categories do people searching Synthesis jobs in California look for? The top searched job categories for Synthesis jobs in California are:
What cities in California are hiring for Synthesis jobs? Cities in California with the most Synthesis job openings:
Synthesis jobs near you
Infographic showing various Synthesis job openings in California as of July 2026, with employment types broken down into 81% Full Time, 16% Part Time, 1% Temporary, and 2% Contract. Highlights an 72% Physical, 4% Hybrid, and 24% Remote job distribution, with an average salary of $137,583 per year, or $66.1 per hour.

Peptide Synthesis Specialist

Ellison Medical Institute

Los Angeles, CA • On-site

$87K - $115K/yr

Full-time

Re-posted 14 days ago

Job description

Job Title: Peptide Synthesis Specialist 
Annual Base Salary: DOE, $87,000-$115,000 along with bonus eligibility and a comprehensive benefits package
Location: Los Angeles, CA
Our Mission
Formerly known as the Ellison Institute of Technology Los Angeles, the Ellison Medical Institute strives to spark innovation, leverage technology, and drive interdisciplinary, patient-centered research to continually enhance health, reimagine and redefine cancer care, and transform lives.
Established in 2016 as a medical research and development center, the Institute features innovation labs for artificial intelligence and molecular analytics and was among the first organizations to vertically integrate the interdisciplinary study and treatment of disease. We offer multifaceted programs, including a preventative medicine and cancer clinic, cross-disciplinary research laboratories, a health policy think-tank, and community outreach and educational programs.
Please visit emila.org for more details.
Job Summary
The Ellison Medical Institute is seeking a Peptide Synthesis Specialist to design, execute, and optimize peptide synthesis workflows, including solid-phase peptide synthesis (SPPS), purification, and analytical characterization.
The role will involve hands-on peptide production, collaboration with cross-functional teams, and continuous process improvement to deliver high-quality, reproducible peptides that support preclinical research and therapeutic development efforts. The ideal candidate will have a strong foundation in peptide synthesis chemistry, HPLC-based purification methods, and peptide analysis techniques.
Why You Should Join Us
  • Build a New Capability from the Ground Up: Help establish high-throughput peptide and protein synthesis and purification operations within an organization expanding its therapeutic discovery capabilities.
  • Direct Scientific Impact: Drive the production and optimization of peptides synthesis to support drug discovery, lead optimization, and preclinical testing.
  • Collaborative Environment: Work closely with design, biological evaluation, and analytical teams to translate synthetic peptides into therapeutic development projects.
  • Technical Ownership: Play a key role in shaping technical standards, designing workflows, and selecting synthesis and characterization methodologies.
  • Innovation and Quality: Contribute to continuous improvement of peptide synthesis optimization, quality and efficiency.

Job Accountabilities:
  • Peptide Synthesis: Perform and optimize peptide synthesis using solid-phase and Fmoc and Boc chemistries; manage automated peptide synthesizer operations and workflows.
  • Purification & Characterization: Execute peptide purification using chromatographic techniques and perform analytical characterization (e.g., LC-MS, UPLC/HPLC) to ensure material meets defined quality standards. Support recombinant protein expression and purification for select targets as required.
  • Quality, Documentation & Compliance: Maintain accurate and complete documentation of synthesis procedures, analytical data, and standard operating procedures, while ensuring adherence to laboratory safety protocols and consistent quality standards across synthesis, purification, and characterization processes.
  • Cross-Functional Collaboration: Collaborate with design, discovery, analytical, and biology teams to align synthesis outputs with experimental needs, and provide scientific insights to support downstream evaluation. Communicate findings clearly with scientific teams.
  • Culture & Leadership: Promote and uphold a team  culture of efficient time management, transparency, innovation, collaboration, and accountability, while maintaining high scientific and technical standards.
ADDITIONAL INFORMATION
Required Education:
  • Bachelor’s in Organic Chemistry, Biochemistry, Peptide Chemistry, Chemical Biology, or a closely related discipline
  • Master’s of Science preferred
Required Experience:
  • Hands-on experience planning  and executing peptide synthesis using SPPS and related methodologies.
  • Strong experience with purification and analytical characterization techniques (e.g., HPLC, LC-MS).
  • Demonstrated ability to troubleshoot synthesis challenges and optimize peptide workflows.
  • Solid understanding of peptide chemistry principles, including protecting group strategies and coupling methods.
  • Excellent time management, teamwork, documentation, and communication abilities.
  • Demonstrated ability to work collaboratively in an interdisciplinary research environment.
Preferred Additional Skills:
  • Experience with recombinant protein expression and purification
  • Familiarity with biophysical techniques for characterizing biomolecular interactions (e.g., SPR)

For the safety and health of employees, guests, and patients, the Ellison Medical Institute may mandate vaccination requirements for employment. The Ellison Medical Institute's policies are always subject to review and change to ensure they are appropriate under the circumstances.
The Ellison Medical Institute is an equal opportunity employer. We believe that an inclusive, collaborative team environment is just as important to our mission as stethoscopes and microscopes. We strive to always provide employees a supportive atmosphere, so they feel confident taking creative risks toward innovation. The Ellison Medical Institute values emotional intelligence and communication with empathy and respect for others. We seek to build a diverse group of people who are curious, have a deep sense of responsibility, and the grit needed to achieve excellence. 

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