By joining Bio-Techne, you'll join a company with a powerful and positive purpose of enabling cutting-edge research in Life Sciences and Clinical Diagnostics. Bio-Techne, and all of its brands, provides tools for researchers to further treat and prevent disease worldwide.
Pay Range:
$87,600.00 - $144,000.00
SeniorScientist, Regenerative Medicine-Customer Applications
Position Summary:
TheRegenerative Medicine- Customer ApplicationsSenior Scientistisakey memberof a dynamic teamfocused ondevelopinginnovative products andapplicationsfor regenerative medicine andorganoidresearch.We areseekinga highly skilled and experienced scientist withdemonstratedexpertiseindiverse organoid workflows, disease modeling, and driving innovation for stem cell-derived therapies.The successful candidate will play a critical role in developing and improving human pluripotent stem cell (hPSC)-based differentiation and characterizationtechniques.
As a part ofthis role,you'llhelp drivesignificant progressin regenerative and personalized medicinesbyjoiningacollaborativeteam of innovators working to create impactful solutions fordrug discovery andclinical trials.This position offers a unique opportunity toutilizethe breadth of Bio-Techne's product portfolioand work closely with variousteams to maximize the impact of ourreagentsolutions.Key responsibilities include developingproductsand applicationsfor expansion, differentiation, and characterization of stem cell derivedorganoidmodels.Experience in culturing stem cells (e.g.iPSC, ESC, MSC or adult stem cells)andin3D culturesystems,including spheroid, organoids -isrequired.
Key Responsibilities:
- Identifyand develop products, workflows,and key culture optimizations (i.e.expansion, differentiation, and characterization) for stem cell-based therapyand organoidresearch andapplication.
- Develop andoptimizerobust and reproducible cell differentiation protocols, analytical methods, and other processes needed to convert human induced pluripotent stem cells (iPSCs) into cellular products and therapeutics.
- Lead core teams and collaborate with cross-functional teams to formulate cell differentiation reagents and protocols for different iPSC-derived cell types.
- Serve as a subject matter expert in organoids, supporting new product initiatives including organoid model development, disease modeling applications, drug screening platforms, and protocol scale-up.
- Develop cell-based, biochemical, and/or molecular assays to characterize the identity and physiology of stem cell-derived differentiated cellsand organoids.
- Plan and perform experiments, analyze data, and generate presentations to inform project progress to widerdepartmentand leadership.
- Provide substantial, high-quality contributions to projects by working independently, communicating effectively withincross-functional team andleverageavailableexpertiseand support across the organization.
- Contribute to corporate scientific activities/roadmaps/strategy.
- Develop scientific content including conference presentations, publications, application notes, webinars and other Sales and Marketing efforts to support and promote Bio-Techne's stem cell, organoids,and regenerative medicine product offerings and services.
- Apply scientific methods and process design principles to improve development,manufacturingand quality control processes.
- Author documentation including standard operating procedures (including Manufacturing and QC) for RUO and GMP products, design verification and validation procedures, and technical reports to support lab operation, development initiatives, and product investigations.
- Stayup to datewith the latest scientific developments and market offerings in the fields of stemcell, organoids,and regenerative medicine.
- Provide subject matterexpertise, mentorship,and leadership to other scientists and research associates acrossthedepartment and the wider Bio-Techne team.
Qualifications & Experience:
- Ph.D. in Biology, Biomedical Engineering, Chemical Engineering, or a related field, with a minimum of 2+ years of industry experience in cell and gene therapy, regenerative medicine, or biomanufacturing.
- The ideal candidatehastranslationalresearch experience applying organoid models to disease biology, drug discovery,and/or therapeutic screening.
- Provenexpertisein process development for stem cell-based therapy research, including scaling workflows from discovery to GMP-compliant manufacturing.
- Hands-on experience with adherent cell culture systems and advanced bioreactor platforms for large-scale cell expansion and differentiation.
- Significant technical expertise/scientific knowledge of autologous or allogeneic cell therapies or differentiation pathways.
- Expertisein fluorescencemicroscopy and standard cell characterization assays (e.g.RT-PCR, flow cytometry, ELISA,andICC)required.High throughput assays or high content imaging experience strongly preferred.Experiencewithgene editingtechnologies (e.g.CRISPR)andbiomaterialsfor advanced cellculturea plus.
- Prior demonstrated experience developing andvalidating/verifying product workflows under design control using a requirements-driven, risk-based approach within the biotech industry or clinical laboratory.
- Strong background in developing andoptimizingdifferentiation protocols for iPSCs or other pluripotent stem cells, with an emphasis on clinical and manufacturing applications.
Knowledge, Skills, and Abilities:
- Self-motivated,action oriented, highly collaborative andteam focused, results driven withhigh levelsof professionalism,responsibilityand positive attitude.
- Astrongtrack recordof independence, scientific productivity, and creative problem-solving.
- Knowledge of regulatory and quality standards for GMP production and experience developing workflows under design control and risk-based approaches.
- Technicalproficiencywith standard cell characterization assays, 3Dculturesystems, and advanced imaging or high-throughput screening platforms.
- Demonstrated ability to lead cross-functional teams, manage complex projects, and provide innovative solutions to technical challenges.
- Track recordof scientific innovation, productivity, and problem-solving in a fast-paced, results-driven environment.
Why Join Bio-Techne:
- We offer competitive insurance benefits starting on day one: medical, dental, vision, life, short-term disability, long-term disability, pet, and legal and ID shield.
- We invest in our employees' financial futures through 401k plans, an employee stock purchase plan (ESPP), Health Saving Account (HSA), Flexible Spending Account (FSA), and Dependent Care FSA.
- We empower our employees develop their careers through mentorship, promotional opportunities, training and development, tuition reimbursement, internship programs, and more.
- We offer employee resource groups, volunteer paid time off, employee events, and charity drives to build a culture of caring and belonging.
- We offer an accrued leave policy with paid holidays, paid time off, and paid parental leave.
- We foster a culture of empowerment and innovation, where employees feel valued and encouraged to bring their new ideas to the table.
Bio-Techne is an E-Verify Employer in the United States.
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.
To protect the interests of all, Bio-Techne will not accept unsolicited resumes from any source other than a candidate application. Any unsolicited resumes sent to Bio-Techne will be considered Bio-Techne property.