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Sr Statistical Programmer Jobs in Boston, MA (NOW HIRING)

Dyne Tx

Senior Director, Biostatistics

Waltham, MA · On-site

$250 - $290/hr

As a senior statistical leader and cross‑functional partner, this role leads statistical ... Management, Statistical Programming, Translational Medicine, Program Management, and other ...

Generate Biomedicines

Data Scientist I

Somerville, MA · On-site

... senior statistical and clinical partners. You will learn to reason carefully under uncertainty ... You will work closely with clinical, statistical, engineering, and product partners to understand ...

AstraZeneca

Senior Manager, Biostatistics

Boston, MA · On-site

$119K - $157K/yr

The Senior Manager, Biostatistics has sufficient experience working as a statistician in the ... Competent statistical programmer (SAS and R) * Knowledge of key technical and regulatory ...

Treeline Biosciences

Head of Biometrics

Watertown, MA · On-site

$310K - $395K/yr

Manage the statistical programming function and ensure delivery of high-quality datasets and ... senior leadership team, delivering timely biometrics insights and presentation support for high ...

Treeline Biosciences

Head of Biometrics

Watertown, MA · On-site

$310K - $395K/yr

Manage the statistical programming function and ensure delivery of high-quality datasets and ... senior leadership team, delivering timely biometrics insights and presentation support for high ...

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Showing results 21-40

All JobsSr Statistical Programmer JobsSr Statistical Programmer Jobs in Boston, MA

Sr Statistical Programmer information

See Boston, MA salary details

$89.6K

$139.4K

$182K

How much do sr statistical programmer jobs pay per year?

As of Aug 8, 2026, the average yearly pay for sr statistical programmer in Boston, MA is $139,378.00, according to ZipRecruiter salary data. Most workers in this role earn between $116,200.00 and $160,800.00 per year, depending on experience, location, and employer.

What is a Sr Statistical Programmer?

Sr Statistical Programmers are experienced professionals who specialize in managing and analyzing complex data sets, typically in the clinical research and pharmaceutical industries. They use statistical software like SAS or R to develop and validate programs that support clinical trials, regulatory submissions, and data reporting. Their responsibilities often include ensuring data quality, creating analysis datasets, generating tables, listings, and figures, and collaborating with statisticians and data managers. Senior-level programmers also mentor junior staff and may oversee project timelines and deliverables. Their expertise is essential for turning raw clinical data into meaningful results that support drug development and regulatory decision-making.

How does a Sr Statistical Programmer typically collaborate with biostatisticians and clinical teams during a clinical trial project?

As a Sr Statistical Programmer, you will work closely with biostatisticians to translate statistical analysis plans into efficient programming code, often using SAS or R. You’ll also regularly interact with clinical data managers and project teams to clarify data requirements, resolve data discrepancies, and ensure the accuracy of deliverables. Effective communication and proactive problem-solving are key, as you may be responsible for leading programming efforts, mentoring junior programmers, and ensuring that all outputs meet regulatory and project timelines. This collaborative environment helps ensure the integrity and reproducibility of clinical trial results.

What are the key skills and qualifications needed to thrive as a Sr Statistical Programmer?

To thrive as a Sr Statistical Programmer, you need strong expertise in statistical programming languages like SAS or R, experience with clinical trial data, and a relevant degree in statistics, mathematics, or a related field. Proficiency with CDISC standards (SDTM, ADaM), data management systems, and regulatory submission tools is typically required. Excellent problem-solving, attention to detail, and effective communication are crucial soft skills for collaborating with cross-functional teams and ensuring high data quality. These skills and qualifications are essential for accurate analyses, regulatory compliance, and successful delivery of clinical research projects.
Sr Statistical Programmer jobs near you
Infographic showing various Sr Statistical Programmer job openings in Boston, MA as of August 2026, with employment types broken down into 1% As Needed, 91% Full Time, 3% Part Time, and 5% Contract. Highlights an 86% Physical, 5% Hybrid, and 9% Remote job distribution, with an average salary of $139,378 per year, or $67 per hour.

Associate Director, Statistical Programming

MapLight Therapeutics

Burlington, MA • Hybrid

Full-time

Re-posted 28 days ago

Job description

What You'll Do: Reporting to the Senior Director, Statistical Programming, the Associate Director will provide statistical and clinical data programming expertise to manage statistical programming activities that support drug development programs and regulatory submissions. This role involves overseeing the creation, validation, and delivery of programming deliverables, ensuring compliance with industry standards, and fostering cross-functional collaboration with biostatistics, data management, clinical, and regulatory teams.

Responsibilities: 

  • Oversee the development and validation of SAS programs to generate datasets (SDTM, ADaM), tables, listings, and figures (TLFs) in compliance with CDISC standards.
  • Ensure the timely and high-quality delivery of programming outputs for regulatory submissions, clinical study reports, and exploratory analyses.
  • Ensure all programming activities align with industry standards (CDISC, ICH, FDA, EMA) and internal SOPs.
  • Programming lead for clinical programs as needed. Hand-on programming work in SAS and other programming languages/tools.
  • Establishes and maintains CRO/vendor partnerships.
  • Act as a liaison between statistical programming and other functions, ensuring clear communication and alignment of goals.
  • Partner with biostatistics, data management, and clinical operations to resolve programming issues and optimize processes.
  • Identify and implement new tools, techniques, and processes to improve efficiency and quality in statistical programming.

Qualifications:

  • Master's degree in statistics, computer science or a related field
  • At least 8 years of statistical programming experience in the pharmaceutical/biotech industry
  • Proven ability to manage CRO relationships and oversee programmed deliverables.
  • Extensive experience in leading statistical programming function for both early and late phase clinical trials, and regulatory submissions (NDA/BLA, MAA)
  • Excellent skills in SAS programming and statistical reporting, knowledge of R and R Shiny desirable
  • In-depth knowledge of CDISC standards for SDTM and ADaM and FDA electronic data submission requirements
  • Familiarity with FDA and ICH regulations and guidelines
  • Excellent written and verbal communication skills, ability to collaborate with a multidisciplinary team and interact effectively in a fast-paced team environment

Location: This is a hybrid role with three days per week in-office in Burlington, Massachusetts.

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