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Sr Software Engineer Jobs in Rochester, MN (NOW HIRING)

As part of the Framework for AI Software Technologies (FAST) program, you will join scientists, engineers, and clinicians to turn prototypes-including generative-AI and large-language-model solutions ...

Software Engineer - Hybrid

Rochester, MN · Hybrid

$102K - $143K/yr

As part of the Framework for AI Software Technologies (FAST) program, you will join scientists, engineers, and clinicians to turn prototypes-including generative-AI and large-language-model solutions ...

As part of the Framework for AI Software Technologies (FAST) program, you will join scientists, engineers, and clinicians to turn prototypes-including generative-AI and large-language-model solutions ...

As part of the Framework for AI Software Technologies (FAST) program, you will join scientists, engineers, and clinicians to turn prototypes-including generative-AI and large-language-model solutions ...

Software Engineer-Mid

Rochester, MN · Hybrid

$119K - $161K/yr

Software Engineering Job Qualifications: Skills: Flask (Web Framework), Python (Programming Language), SQLAlchemy Certifications: None Experience: 5 + years of related experience US Citizenship ...

Senior Media Systems Engineer

Rochester, MN · On-site

$95K - $131K/yr

The Senior Media Systems Engineer is accountable for project results and goals set by Unit Head and ... hardware and software-based media systems and projects in the supported areas. Is directly ...

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Sr Software Engineer information

See Rochester, MN salary details

$76.7K

$145.7K

$195.2K

How much do sr software engineer jobs pay per year?

As of Jul 9, 2026, the average yearly pay for sr software engineer in Rochester, MN is $145,655.00, according to ZipRecruiter salary data. Most workers in this role earn between $124,500.00 and $164,200.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Sr Software Engineer, and why are they important?

To thrive as a Sr Software Engineer, you need advanced programming skills, a strong grasp of software design principles, and typically a degree in computer science or a related field. Expertise with development frameworks, version control systems like Git, and familiarity with cloud platforms or containerization tools is often required. Exceptional problem-solving abilities, clear communication, and leadership skills set top performers apart in collaborative environments. These competencies ensure the efficient delivery of high-quality software solutions and effective mentorship within development teams.

What engineers make $300,000 a year?

Senior software engineers with extensive experience, specialized skills in areas like machine learning or cloud computing, and working at large tech companies or in high-cost-of-living regions can earn $300,000 or more annually. Compensation often includes base salary, bonuses, and stock options, especially for those in leadership or highly technical roles.

What does a SR software engineer do?

A senior software engineer designs, develops, tests, and maintains software applications and systems. They often lead projects, review code, mentor junior team members, and collaborate with cross-functional teams using programming languages and tools like Java, Python, or C++. They also ensure software quality, performance, and security standards are met.

What engineer makes $500,000 a year?

Senior software engineers at top tech companies or those in specialized roles such as machine learning or cloud architecture can earn $500,000 or more annually, often including bonuses and stock options. Achieving this level typically requires extensive experience, advanced skills, and working in high-paying industries or companies.

What are some common challenges Sr Software Engineers face when leading technical projects?

Sr Software Engineers often encounter challenges such as balancing hands-on coding with mentoring less experienced team members, managing shifting project requirements, and ensuring timely delivery while maintaining high code quality. They are frequently responsible for making critical architectural decisions and resolving complex technical issues that arise during the development process. Additionally, effective communication with cross-functional teams and stakeholders is key to aligning technical solutions with business goals.

What are Sr Software Engineers?

Sr Software Engineers are experienced professionals who design, develop, and maintain complex software systems. They often lead technical projects, mentor junior team members, and collaborate with stakeholders to ensure software meets business needs. In addition to coding, they are responsible for making architectural decisions, reviewing code, and ensuring best practices are followed. Sr Software Engineers typically have several years of industry experience and deep expertise in specific programming languages or technologies.

Can you make $500,000 as a software engineer?

Senior software engineers at large tech companies or in specialized fields such as AI or cybersecurity can earn $500,000 or more annually, often including bonuses and stock options. However, such high compensation levels are typically reserved for experienced professionals in senior or executive roles, and salaries vary based on location, company size, and individual skills.
What are popular job titles related to Sr Software Engineer jobs in Rochester, MN? For Sr Software Engineer jobs in Rochester, MN, the most frequently searched job titles are:
What job categories do people searching Sr Software Engineer jobs in Rochester, MN look for? The top searched job categories for Sr Software Engineer jobs in Rochester, MN are:
What cities near Rochester, MN are hiring for Sr Software Engineer jobs? Cities near Rochester, MN with the most Sr Software Engineer job openings:
Infographic showing various Sr Software Engineer job openings in Rochester, MN as of July 2026, with employment types broken down into 92% Full Time, 5% Part Time, and 3% Contract. Highlights an 89% Physical, 3% Hybrid, and 8% Remote job distribution, with an average salary of $145,655 per year, or $70 per hour.
Software Engineer - Hybrid

Software Engineer - Hybrid

Mayo Clinic

Rochester, MN • On-site

Full-time

Medical, Dental, Vision, Retirement

Posted 19 days ago


Mayo Clinic rating

7.8

Company rating: 7.8 out of 10

Based on 688 frontline employees who took The Breakroom Quiz

105th of 880 rated healthcare providers


Job description


The Mayo Clinic IT Radiology AI unit is seeking a talented and motivated professional to contribute to the advancement of Radiology Artificial Intelligence initiatives. As part of the Framework for AI Software Technologies (FAST) program, you will join scientists, engineers, and clinicians to turn prototypes-including generative-AI and large-language-model solutions-into secure, cloud-native applications that enhance patient care.
In this collaborative role, you will analyze requirements, develop robust software applications, validate integrations with clinical systems, and provide operational support for production workflows. Success is built on experience with Python coding, modern cloud platforms, machine learning, and medical imaging. Familiarity with Generative AI, LLMs, FHIR, Google Cloud, and Epic integrations is especially valuable.
Responsibilities:
• Participate in DevOps, Agile, continuous development and integration frameworks.
• Programming in high-level languages such as Python, Go, C, C++, C#, Java, etc.
• Work on deployment automation/configuration management with tools including but not limited to ADO, GitHub, Azure Pipelines, Terraform following a DevOps model.
• Ensure all appropriate documentation of processes and source code is created and maintained.
• Communicate effectively with peers, leaders, and customers throughout the organization.
• Participate in expert level troubleshooting and resolve problems through root cause analysis, data, and system investigation.
• Continue to build knowledge of the organization, processes, and customers.
• Use prescribed guidelines or policies to analyze and resolve problems.
• Receive a moderate level of guidance and direction.
• Participate with the team in providing 24/7 call support.
Qualifications
Bachelor's degree in Computer Science/Engineering or related field; Or an Associates' degree in Computer Science/Engineering or related field with an additional 2 years of experience as described below.
• Working knowledge and experience of Software Engineering with a minimum of internships and a minimum of 1 yr. of experience, or 2 yrs of experience coding applications or services in a high-level language (Python, C, C++, Go, Java, C# etc.).
• Familiarity with modern tools for generative AI, including large language models, prompt engineering, and retrieval augmented generation.
• Demonstrated problem solving and time management skills.
• Strong technical aptitude for designing and implementing software solutions.
• Experience with modern application development frameworks.
• Knowledge of professional software-engineering practices across the full development life cycle-coding standards, code reviews, source-control management, build processes, testing, and operations.
• Deep hands-on technical expertise coupled with excellent verbal and written communications.
• Experience with Agile software development methods.
Preferred Technology Experience:
• Ability to use a wide variety of open-source technologies and cloud-based services.
• Experience with cloud environments (Google, AWS, Azure).
• Experience with Python programming language.
• Experience in databases, analytics, big data systems or business intelligence products.
• Experience building high-performance, highly available and scalable distributed systems.
• Experience developing software for healthcare related industries.
This vacancy is not eligible for sponsorship/we will not sponsor or transfer visas for this position. Mayo Clinic DOES NOT participate in the F-1 STEM OPT extension program.
About Us
Why Mayo Clinic
Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans - to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
Benefits Highlights
  • Medical: Multiple plan options.
  • Dental: Delta Dental or reimbursement account for flexible coverage.
  • Vision: Affordable plan with national network.
  • Pre-Tax Savings: HSA and FSAs for eligible expenses.
  • Retirement: Competitive retirement package to secure your future.

About the Team
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is.
Equal Opportunity
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law". Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.

What Mayo Clinic employees say

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Mayo Clinic logo

About Mayo Clinic

Sourced by ZipRecruiter

Mayo Clinic is the largest integrated, not-for-profit medical group practice in the world. We're building the future, one where the best possible care is available to everyone — and more people can heal at home. Our relentless research turns into earlier diagnoses and new cures. That's how we inspire hope in those who need it most. At Mayo Clinic, experts work together to solve the most challenging unmet needs of patients. Our history of innovation dates back almost 150 years, when brothers Will and Charlie Mayo pioneered an integrated, team-based approach to medicine. Today, that trailblazing spirit drives innovations like Mayo Clinic Platform — which powers new technologies to change how care is delivered to all.

Industry

Hospitals

Company size

10,000+ Employees

Headquarters location

Rochester, MN, US

Year founded

1919