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Sr Python Engineer Jobs in Lowell, MA (NOW HIRING)

Senior Back-End Engineer Location: Cambridge, MA | In-Person About us We are a Seed Stage ... Python, JavaScript, TypeScript, Java, C++, Go APIs & RPCs: REST, gRPC, GraphQL Databases: SQL ...

Senior Back-End Engineer Location: Cambridge, MA | In-Person About us We are a Seed Stage ... Python, JavaScript, TypeScript, Java, C++, Go APIs & RPCs: REST, gRPC, GraphQL Databases: SQL ...

Senior Software Engineer

Woburn, MA · On-site +1

$134K - $184K/yr

STR is hiring a Senior Software Engineer to be part of a multi-disciplinary team that transforms ... Implement real-time systems in C/C++ and Python from verified algorithms written in higher-level ...

Senior DevOps Engineer

Cambridge, MA · Remote

$143.20K - $184K/yr

... ENGINEER We are seeking a Senior DevOps Engineer to implement and manage our cloud based ... Python, bash, other scripting language experience is required. Ansible, Terraform, or equivalent ...

Senior Systems Engineer

Tewksbury, MA · On-site

$112.60K - $154.10K/yr

Senior Systems Engineer - LTAMDS Radar Work Location: On-Site Position Overview Looking for a ... Experience with C++, Python, or similar. * Experience with generating technical documentation, such ...

Senior Software Engineer

Waltham, MA · Hybrid

$132.20K - $174.20K/yr

Xometry is seeking a Senior Software Engineer to join our software engineering organization. In ... Reading, writing, and reviewing code written in HTML, Typescript/Javascript/React, Python, and Rust

Senior NLP Engineer

Boston, MA

$113.90K - $156.40K/yr

Senior Natural Language Processing (NLP) Engineer Would you like to contribute creatively to a ... Linux, Python, Bash, SQL, JavaScript * Excellent organizational and communication skills What's in ...

AI Engineer Location: Boston, MA - 4 days/week onsite-locals only with DL copy Pay rate: Senior ... The ideal candidate has strong experience with a modern AI/ML stack, including a profound Python ...

Senior Software Engineer

Boston, MA · On-site

$133.10K - $175.50K/yr

Senior Software Engineer Reports to: Sr. Manager, Software Engineering Location: Houston, TX; ... Advanced proficiency in Python, FastAPI, PyTest, Celery, and other Python frameworks * Deep ...

Senior DevSecOps Engineer

Boston, MA · On-site

$124.40K - $170.60K/yr

Senior DevSecOps Engineer Location: Boston, MA Employment Type: Full-Time Experience: 10+ Years ... Develop automation scripts and workflows using Python, Bash, Go, or PowerShell . * Integrate SIEM ...

Senior Software Engineer

Waltham, MA · On-site

$132.20K - $174.20K/yr

Xometry is seeking a Senior Software Engineer to join our software engineering organization. In ... Reading, writing, and reviewing code written in HTML, Typescript/Javascript/React, Python, and Rust

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Sr Python Engineer information

See Lowell, MA salary details

$22.8K

$138.8K

$200.8K

How much do sr python engineer jobs pay per year?

As of May 30, 2026, the average yearly pay for sr python engineer in Lowell, MA is $138,819.00, according to ZipRecruiter salary data. Most workers in this role earn between $109,600.00 and $163,100.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Sr Python Engineer, and why are they important?

To thrive as a Sr Python Engineer, you need advanced proficiency in Python programming, strong knowledge of software design patterns, and experience with scalable application development, often supported by a degree in computer science or related field. Familiarity with frameworks like Django or Flask, version control systems such as Git, and cloud platforms like AWS or Azure is typically required, with certifications in cloud or Python development considered a plus. Excellent problem-solving abilities, strong communication, and leadership skills help you collaborate effectively and mentor junior engineers. These competencies are critical for delivering robust, efficient solutions and driving technical excellence within development teams.

What are some common challenges Sr Python Engineers face when working on large-scale applications?

Sr Python Engineers often encounter challenges related to maintaining code quality and scalability as applications grow. Managing dependencies, ensuring optimal performance, and coordinating with cross-functional teams can be complex, especially in distributed systems. Additionally, integrating new technologies or frameworks while maintaining backward compatibility requires careful planning and communication. Proactive code reviews, clear documentation, and collaborative problem-solving are essential to overcoming these challenges.

What does a Sr Python Engineer do?

A Sr Python Engineer is an experienced software developer who specializes in designing, developing, and maintaining applications using the Python programming language. They often lead projects, mentor junior engineers, and work on complex problems that require deep technical expertise. Their responsibilities may include writing efficient code, optimizing performance, integrating with APIs or databases, and ensuring the overall quality of software solutions. Additionally, they may collaborate with cross-functional teams to deliver robust and scalable applications.

What is the difference between Sr Python Engineer vs Python Developer?

AspectSr Python EngineerPython Developer
Required CredentialsBachelor's degree in CS or related field, experience in Python, often some leadership skillsBachelor's degree in CS or related field, strong Python skills, often less emphasis on leadership
Work EnvironmentTeam lead, project architect, involved in system design and optimizationCode writing, feature development, bug fixing
Employer & Industry UsageTech companies, startups, enterprise softwareWeb development, data analysis, automation projects

While both roles require strong Python skills, Sr Python Engineers typically have more experience, leadership responsibilities, and involvement in system architecture, whereas Python Developers focus more on coding and feature implementation.

What are popular job titles related to Sr Python Engineer jobs in Lowell, MA? For Sr Python Engineer jobs in Lowell, MA, the most frequently searched job titles are:
What job categories do people searching Sr Python Engineer jobs in Lowell, MA look for? The top searched job categories for Sr Python Engineer jobs in Lowell, MA are:

Sr Backend Engineer

Venus Consultancy

Boston, MA • On-site

Full-time

Posted 2 days ago


Job description

Role: Senior Back-End Engineer
Location: Cambridge, MA | In-Person
 
About us
We are a Seed Stage Generative AI startup based in Cambridge, MA. Our mission is to automate custom software creation and unlock the next industrial revolution. Backed by top-tier investors, our founders have a track record of success, holding dozens of Generative AI patents and leading previous startups to success.
 
About the Role
We are seeking a Senior Back-End Engineer to take ownership of various parts of our tech stack. Working directly with our CTO and founding team, you’ll play a crucial role in product development, technical decision-making, and shaping the company’s culture.
We are solving challenging engineering problems at the intersection of AI, cloud infrastructure, and enterprise software development. This role is ideal for someone who is curious, driven, and eager to build from the ground up.
 
What Success Looks Like
You write, review, and deploy high-quality, production-ready code.
You use Generative AI tools to enhance software development and increase efficiency.
You make technical architecture decisions that balance speed, quality, and safety.
You take ownership of your work, ensuring reliability and scalability.
You thrive in an in-person, fast-paced startup environment and collaborate effectively with cross-functional teams.
You can learn quickly, even when working with technologies outside your comfort zone.
You contribute to our engineering culture, setting the foundation for best practices and long-term success.
 
Areas of Ownership
As a Senior Back-End Engineer, you’ll be expected to demonstrate generalist capabilities with deep expertise in Back-End Technologies.
Required Skills & Experience
Expertise in Python, Terraform, and GCP (Google Cloud Platform)
Experience with at least some of the following:
Backend Frameworks & Technologies: Node.js, NuxtJS, Express.js, Python
Cloud Platforms: Google Cloud, AWS, Azure, VercelProgramming 
Languages: Python, JavaScript, TypeScript, Java, C++, Go
APIs & RPCs: REST, gRPC, GraphQL
Databases: SQL, NoSQL, PostgreSQL, MongoDB, Firebase
CI/CD Tools: Jenkins, CircleCI, GitLab
Version Control: Git, Perforce
Microservices Architecture
 
Ways to Stand Out
Experience with AI Platforms: OpenAI, Anthropic, Hugging Face, Vertex AI, Bedrock, SageMaker
Enterprise-Scale Development: Building applications with >99% SLAs
Extensive Experience in Python, Terraform, and GCP
 
Our Culture
We operate with a low-ego, high-output mindset. Our team moves fast, prioritizing action over perfection. We believe in work-life balance, making time for personal well-being while maintaining a high-performance environment.
We prioritize speed on all two-way door decisions.
We encourage curiosity, autonomy, and problem-solving.
We value collaboration but also expect team members to own their work.
We believe in being everyday athletes—optimizing mental and physical health for peak performance.
We leave the office in time for dinner with our families most nights.
 
Are You Up for the Challenge?
Startups are demanding, ever-changing, and require high levels of autonomy. If that excites you rather than intimidates you, we’d love to hear from you!