... spatial transcriptomics, medicinal chemistry, bioinformatics, and flow cytometry, humanized mouse models, among others. The Institute's location adjacent to the campuses of the University of ...
... spatial transcriptomics, medicinal chemistry, bioinformatics, and flow cytometry, humanized mouse models, among others. The Institute's location adjacent to the campuses of the University of ...
Spatial Transcriptomics information
What is spatial transcriptomics?
Spatial transcriptomics is an advanced technique that allows scientists to measure gene expression within the spatial context of tissue samples. Unlike traditional RNA sequencing, which loses information about where each gene is expressed, spatial transcriptomics preserves the physical location of gene activity in tissues. This helps researchers better understand how cells function within their native environments and interact with neighboring cells, which is especially valuable in fields like cancer research, neuroscience, and developmental biology. The method combines microscopy, molecular biology, and computational analysis to produce detailed maps of gene expression.
What are some common challenges faced by professionals working in spatial transcriptomics, and how can they be addressed?
Professionals in spatial transcriptomics often encounter challenges related to handling large, complex datasets and integrating spatial information with gene expression data. Ensuring high-quality sample preparation and mastering advanced imaging or sequencing technologies are also frequent hurdles. These challenges can be addressed by collaborating closely with multidisciplinary teams—including bioinformaticians, molecular biologists, and imaging specialists—and staying up-to-date with the latest software tools and protocols. Continuous learning and effective communication within the team are key to overcoming technical and analytical obstacles in this rapidly evolving field.
What are the key skills and qualifications needed to thrive as a Spatial Transcriptomics Scientist, and why are they important?
To thrive as a Spatial Transcriptomics Scientist, you need a strong background in molecular biology, genomics, and bioinformatics, typically supported by an advanced degree in a life science field. Familiarity with spatial transcriptomics platforms (such as 10x Genomics Visium), next-generation sequencing (NGS) technologies, and data analysis tools like R or Python is essential. Strong problem-solving skills, attention to detail, and effective communication are important soft skills for collaborating on interdisciplinary research projects. These skills and qualities are crucial for generating high-quality spatial gene expression data and translating findings into meaningful biological insights.
What are popular job titles related to Spatial Transcriptomics jobs in Wisconsin? For Spatial Transcriptomics jobs in Wisconsin, the most frequently searched job titles are:
What job categories do people searching Spatial Transcriptomics jobs in Wisconsin look for? The top searched job categories for Spatial Transcriptomics jobs in Wisconsin are:
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Posted 20 days ago
Job description
The Wistar Institute is a world leader in early-stage discovery science in the areas of cancer, immunology, and infectious disease. Wistar is committed to accelerating research advances from bench to bedside through brilliant science and distinctive approaches to collaboration among scientific investigators and academic and industry partners. Wistar’s dynamic environment supports the advancement of discoveries that will change the future of human health.
The Wistar Institute is seeking outstanding candidates for faculty positions at the Assistant and Associate Professor level in the Wistar HIV Cure and Viral Diseases Center. Areas of particular high interest include a focus on molecular virology of integrated provirus, AI/bioinformatics approaches to HIV reservoir analysis and immunotherapy. Candidates with research focuses using HIV molecular virology, novel tools and approaches for target identification/validation, pathogenesis, approaches in humanized mice or other novel animal models, in vivo screening systems, CRISPR-Cas/editing, single cell and immune profiling approaches are encouraged to apply.
Applicants who have established strong publication track records and a trajectory toward or established independent research supported by extramural funding are preferred. Candidates with current funding will be given priority. The successful candidates will be expected to pursue extramurally-funded competitive research programs with a primary focus on basic and/or translational studies in the context of HIV Cure and Viral Diseases.
The Wistar Institute is an exceptional institute for advancing a career in research. It is among the most accomplished U.S. institutes in the area of translational vaccine/biologic research. The Wistar Institute is the nation’s first independent biomedical research Institute with long-standing NCI Cancer Center designation. It has a strong technology transfer focus for biomedical research. The Institute offers a highly competitive start-up package in addition to an outstanding and interactive collaborative research environment.
The Institute offers a state-of-the-art vivarium and access to outstanding core facilities in proteomics and metabolomics, genomics, microscopy, high-throughput molecular screening, spatial transcriptomics, medicinal chemistry, bioinformatics, and flow cytometry, humanized mouse models, among others. The Institute’s location adjacent to the campuses of the University of Pennsylvania, Children’s Hospital of Philadelphia, and Drexel University, provides for a wonderful work and living environment for vigorous academic and clinical collaborations. Wistar is a very attractive destination for training opportunities for undergraduate, graduate students, and postdoctoral fellows.
Applications will be reviewed as received and will be accepted until the positions are filled. To ensure timely consideration, applications will be reviewed using a rolling format. The application should include: a curriculum vitae, a summary of past and future research interests (no more than 3 pages), and history of accomplishments, talks and research funding support (as applicable). Applications (submitted as a single PDF) should be sent by e-mail to: Maria Colelli, Faculty Search Coordinator, (mcolelli@wistar.org), The Wistar Institute, 3601 Spruce Street, Philadelphia, PA 19104.
For more information about The Wistar Institute please visit our website at www.wistar.org.