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Spatial Transcriptomics Jobs in California (NOW HIRING)

... cell and spatial transcriptomics, multiomics and related technologies. The successful applicant will: 1) play a key role in developing and rigorously testing new methods in the above areas; 2) ...

Prepare and process samples for spatial omics platforms, including multiplexed protein imaging and spatial transcriptomics, with both RNA- and protein-based tagging approaches * Develop, optimize ...

Experience in multi-omics analyses and integration (including RNA-seq, ATAC-seq - bulk, single cell - spatial transcriptomics, proteomics, metabolomics, ChIP-seq and similar, long read RNA-seq, small ...

Director Pathology

San Diego, CA · Hybrid

$204K - $379K/yr

Ability to synthesize complex molecular datasets (RNA-seq, proteomics, spatial transcriptomics) in the context of tissue biology and pathology. Strong cross-functional influence and comfort operating ...

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Spatial Transcriptomics information

What is spatial transcriptomics?

Spatial transcriptomics is an advanced technique that allows scientists to measure gene expression within the spatial context of tissue samples. Unlike traditional RNA sequencing, which loses information about where each gene is expressed, spatial transcriptomics preserves the physical location of gene activity in tissues. This helps researchers better understand how cells function within their native environments and interact with neighboring cells, which is especially valuable in fields like cancer research, neuroscience, and developmental biology. The method combines microscopy, molecular biology, and computational analysis to produce detailed maps of gene expression.

What are some common challenges faced by professionals working in spatial transcriptomics, and how can they be addressed?

Professionals in spatial transcriptomics often encounter challenges related to handling large, complex datasets and integrating spatial information with gene expression data. Ensuring high-quality sample preparation and mastering advanced imaging or sequencing technologies are also frequent hurdles. These challenges can be addressed by collaborating closely with multidisciplinary teams—including bioinformaticians, molecular biologists, and imaging specialists—and staying up-to-date with the latest software tools and protocols. Continuous learning and effective communication within the team are key to overcoming technical and analytical obstacles in this rapidly evolving field.

What are the key skills and qualifications needed to thrive as a Spatial Transcriptomics Scientist, and why are they important?

To thrive as a Spatial Transcriptomics Scientist, you need a strong background in molecular biology, genomics, and bioinformatics, typically supported by an advanced degree in a life science field. Familiarity with spatial transcriptomics platforms (such as 10x Genomics Visium), next-generation sequencing (NGS) technologies, and data analysis tools like R or Python is essential. Strong problem-solving skills, attention to detail, and effective communication are important soft skills for collaborating on interdisciplinary research projects. These skills and qualities are crucial for generating high-quality spatial gene expression data and translating findings into meaningful biological insights.
What cities in California are hiring for Spatial Transcriptomics jobs? Cities in California with the most Spatial Transcriptomics job openings:
Scientist 2-Spatial Biology and Biophysics

Scientist 2-Spatial Biology and Biophysics

10x Genomics

Pleasanton, CA • On-site

$139K - $188K/yr

Full-time

Medical, Retirement

Posted 8 days ago


Job description

About the role:We are looking for an exceptional, multidisciplinary scientist to drive new research and product development efforts in our Spatial Biology department. The ideal candidate will have a proven track-record in molecular biology and biophysics with extensive experience designing and working with biomolecule imaging platforms (including 10x Genomics Xenium). This position necessitates a deep understanding of molecular biology as you will be applying your skills and knowledge to optimize and evaluate new assays in the area of spatial transcriptomics. Additionally, this role will require you to interact closely with colleagues in several departments including computational biology, software, engineering and microfluidics. You should have a strong analytical background, be driven by developing revolutionary new products and technologies, and enjoy working in a fast-paced, innovative and truly multi-disciplinary environment.
What you will be doing:
The successful candidate will contribute molecular biology and biophysics expertise and leadership to cross-disciplinary product development teams to ensure project milestones and technological specifications are met.
Design and execute experiments using novel imaging and biochemistry platforms integral to various spatial technology platforms under development at 10x Genomics. This includes in-depth analysis and reporting of your data through documentation and presentations to internal groups.
Work closely with computational biologists and optical engineers to interpret data generated by novel optical and biochemical assays.
Develop demonstrated and robust protocols that will be used internally across various teams during product development.
Minimum Requirements:
  • PhD in Molecular Biology, Biophysics, Physical Chemistry or related field.
  • 3+ years of relevant experience in situ hybridization, imaging and spatial techniques, preferably in the Biotechnology industry.
  • Proven ability to design novel molecular biology assay schemes, as evidenced by peer-reviewed publications or published patents.
  • Strong analytical background
  • Strong organizational skills.
  • Strong written and oral communication skills.
  • Strong troubleshooting and problem solving skills.
  • Ability to work in a fast-paced and quickly changing environment.
  • Desire to build game-changing technologies and impact the world of life science research.

Preferred Skills and Experience:
  • Experience with the 10x Genomics Xenium platform is a plus.
  • Fluency in R, Python or AI-aided coding to perform ad-hoc analysis is a plus.
  • Skills in image analysis are a plus.

#LI-MH1 #LI-Onsite
Below is the base pay range for this full-time position. The actual base pay will depend on several factors unique to each candidate, including one's skills, qualifications, and experience. At 10x, base pay is also just one component of the Company's total compensation package. This role is also eligible for 10x's equity grants, its comprehensive health and retirement benefit programs, and its annual bonus program or sales incentive program. During the hiring process, your 10x recruiter can share more about the Company's total compensation package.
Pay Range
$139,700-$188,900 USD
About 10x Genomics
At 10x Genomics, accelerating our understanding of biology is more than a mission for us. It is a commitment. This is the century of biology, and the breakthroughs we make now have the potential to change the world.
We enable scientists to advance their research, allowing them to address scientific questions they did not even know they could ask. Our tools have enabled fundamental discoveries across biology including cancer, immunology, and neuroscience.
Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment. We know that behind every scientific breakthrough, there is a deep infrastructure of talented people driving the life sciences industry and making it possible for scientists and clinicians to make new strides. We are dedicated to finding the very best person for every aspect of our work because the innovations and discoveries that we enable together will lead to better technologies, better treatments, and a better future. Find out how you can make a 10x difference.
Individuals seeking employment at 10x Genomics are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation, or any other characteristic protected by applicable law.
10x does not accept unsolicited applicants submitted by third-party recruiters or agencies. Any resume or application submitted to 10x without a vendor agreement in place will be considered unsolicited and property of 10x, and 10x will not pay a placement fee.
Please be aware of recruitment scams impersonating 10x Genomics. All recruiting communication will come from email addresses @10xgenomics.com. We also want to encourage you to apply to 10x Genomics positions directly on our careers site, Careers.10xgenomics.com or from reputable third party sites, such as LinkedIn or Indeed. We will never request payment or sensitive personal information during the recruiting process.