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Single Cell Rna Sequencing Phd Jobs in Frederick, MD

Axle

Bioinformatics/Data Scientist

Frederick, MD

The successful candidate will analyze complex datasets including single-cell RNA sequencing, bulk ... Candidates must hold a PhD in bioinformatics, computational biology, biostatistics, or a related ...

Axle

Bioinformatics/Data Scientist

Frederick, MD

The successful candidate will analyze complex datasets including single-cell RNA sequencing, bulk ... Candidates must hold a PhD in bioinformatics, computational biology, biostatistics, or a related ...

Axle

Bioinformatics/Data Scientist

Frederick, MD · On-site

The successful candidate will analyze complex datasets including single-cell RNA sequencing, bulk ... Candidates must hold a PhD in bioinformatics, computational biology, biostatistics, or a related ...

Axle

Data Scientist II

Rockville, MD

... seq, single-cell RNA-seq (scRNA-seq), spatial transcriptomics, Digital Spatial Profiling (DSP), whole genome and exome sequencing (WGS/WES), metagenomics, metabolomics, and proteomics, as well as ...

Axle

Genomics Technician

Rockville, MD

Perform bulk RNA-Seq, scRNA-Seq, CITE-Seq, ATAC-Seq, and other immune profiling single-cell assays. * Prepare and QC RNA and DNA samples for sequencing. * Perform routine maintenance, operation and ...

Axle

Genomics Technician

Rockville, MD · On-site

$80K - $90K/yr

Perform bulk RNA-Seq, scRNA-Seq, CITE-Seq, ATAC-Seq, and other immune profiling single-cell assays. * Prepare and QC RNA and DNA samples for sequencing. * Perform routine maintenance, operation and ...

Axle

Genomics Technician

Rockville, MD · On-site

$80K - $90K/yr

Perform bulk RNA-Seq, scRNA-Seq, CITE-Seq, ATAC-Seq, and other immune profiling single-cell assays. * Prepare and QC RNA and DNA samples for sequencing. * Perform routine maintenance, operation and ...

Guidehouse

Scientist

Gaithersburg, MD · On-site

$74K - $124K/yr

... single cell cloning, and top clone selection. * Draft and verify data for CMC (Chemistry ... PhD in biological science or related field with at least two (2) years of experience or master ...

Guidehouse

Scientist

Gaithersburg, MD · On-site

$74K - $124K/yr

... single cell cloning, and top clone selection. * Draft and verify data for CMC (Chemistry ... PhD in biological science or related field with at least two (2) years of experience or master ...

GeneDx, Inc

Senior Clinical Scientist

Gaithersburg, MD · On-site

Senior Clinical Scientist Whole Exome Sequencing Program (WES) GeneDx, Inc Gaithersburg, MD MD/PhD ... Employee Discounts (cell phone service, movie tickets, etc.) * Regular performance appraisals

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How much do single cell rna sequencing phd jobs pay per hour?

As of Aug 21, 2026, the average hourly pay for single cell rna sequencing phd in Frederick, MD is $35.31, according to ZipRecruiter salary data. Most workers in this role earn between $28.94 and $40.14 per hour, depending on experience, location, and employer.

What is a single cell RNA sequencing PhD?

A Single Cell RNA Sequencing PhD is a doctoral degree focused on the study and application of single-cell RNA sequencing (scRNA-seq) technologies. This field involves analyzing the gene expression profiles of individual cells, allowing researchers to understand cellular heterogeneity and complex biological processes at a granular level. PhD students in this area typically conduct original research, develop computational methods, and advance our understanding of cell biology, disease mechanisms, and potential therapeutic targets. Graduates often pursue careers in academia, biotechnology, or pharmaceutical research.

What are the key skills and qualifications needed to thrive as a single cell RNA sequencing PhD, and why are they important?

To thrive as a Single Cell RNA Sequencing PhD, you need a strong background in molecular biology, bioinformatics, and genomics, typically supported by a PhD in a relevant field. Proficiency with single-cell sequencing platforms (e.g., 10x Genomics), next-generation sequencing (NGS) technologies, and computational analysis tools like R or Python is essential. Critical thinking, problem-solving, and effective communication are crucial soft skills for interpreting complex data and collaborating within multidisciplinary teams. These skills and qualifications are vital for designing robust experiments, analyzing high-dimensional data, and translating findings into impactful biological insights.

What are some common challenges faced by researchers in a single cell RNA sequencing PhD role, and how can they be addressed?

One of the main challenges in a Single Cell RNA Sequencing PhD role is managing and interpreting large, complex datasets generated from single-cell experiments. Researchers must be proficient in both wet-lab techniques and bioinformatics analysis, often requiring collaboration with computational biologists. Another challenge is ensuring sample quality and minimizing technical variability, which can significantly impact data reliability. Staying updated with rapidly evolving sequencing technologies and analytical tools is crucial, as is developing strong problem-solving skills to troubleshoot experimental or computational issues.

What is the difference between Single Cell Rna Sequencing Phd vs Single Cell Data Analyst?

AspectSingle Cell Rna Sequencing PhdSingle Cell Data Analyst
Required CredentialsPhD in Biology, Genetics, or related fieldBachelor's or Master's in Data Science, Biology, or related field
Work EnvironmentResearch labs, biotech companies, academic institutionsBiotech firms, research organizations, healthcare companies
Industry UsageDesigning experiments, interpreting sequencing data, publishing researchAnalyzing sequencing datasets, creating reports, data visualization

The Single Cell Rna Sequencing Phd typically involves designing experiments and interpreting complex sequencing data, requiring advanced research skills. In contrast, a Single Cell Data Analyst focuses on analyzing datasets, generating insights, and visualizing data, often with less emphasis on experimental design. Both roles are vital in the biotech industry but differ in their focus and required expertise.

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Single Cell Rna Sequencing Phd jobs near you
Infographic showing various Single Cell Rna Sequencing Phd job openings in Frederick, MD as of August 2026, with employment types broken down into 1% Locum Tenens, 1% As Needed, 73% Full Time, 22% Part Time, and 3% Contract. Highlights an 92% Physical, 3% Hybrid, and 5% Remote job distribution, with an average salary of $73,443 per year, or $35.3 per hour.

Bioinformatics/Data Scientist

Axle

Frederick, MD

Full-time

Re-posted 2 days ago

Job description

(ID: 2025-0696)


Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

Axle is seeking a Bioinformatics/Data Scientist to join our vibrant team at the National Institutes of Health (NIH) supporting the Standardized Organoid Model Center in Frederick, MD. The Standardized Organoid Model Center is an NIH-funded initiative dedicated to advancing organoid research through the development of validated, reproducible, and well-characterized organoid models. The center brings together interdisciplinary teams of researchers to establish standardized protocols, develop quality control measures, and create resources that will benefit the broader organoid research community.

Benefits We Offer:

  • 100% Medical, Dental & Vision Coverage for Employees
  • Paid Time Off and Paid Holidays
  • 401K match up to 5%
  • Educational Benefits for Career Growth
  • Employee Referral Bonus
  • Flexible Spending Accounts:
    • Healthcare (FSA)
    • Parking Reimbursement Account (PRK)
    • Dependent Care Assistant Program (DCAP)
    • Transportation Reimbursement Account (TRN)

Cover Letter Required — Please Answer the Following Questions and Submit Application at: Bioinformatics/Data Scientist
To be considered for this position, please upload a document as your Cover Letter that answers the six questions below. Applications submitted without this document will not be considered.

  1. What experience do you have working with large datasets and compute clusters?
  2. Describe your experience building workflows/pipelines and/or using bioinformatics software and tools to analyze data.
  3. What programming languages are you comfortable using for bioinformatics data analysis?
  4. What bioinformatics areas are you familiar with? (e.g., single cell, bulk genomics, transcriptomics, epigenetics, flow, spatial, metagenomics, etc.)
  5. What life science disciplines do you have experience in? (e.g., immunology, infectious disease, cancer research, etc.)
  6. Provide examples of basic machine learning/AI concepts and/or how you've applied them in bioinformatics data analysis.

Overview

The Bioinformatics/Data Scientist will conduct comprehensive analyses of multi-omics data generated from organoid systems and corresponding normal tissues. This position is central to the SOM Center's research objectives, focusing on characterizing organoid fidelity, identifying biomarkers of successful differentiation, and developing computational frameworks for organoid quality assessment.

Responsibilities

  • The successful candidate will analyze complex datasets including single-cell RNA sequencing, bulk RNA sequencing, proteomics, and metabolomics data from various organoid systems and their tissue counterparts.
  • The position will develop and implement computational pipelines for data processing, quality control, and statistical analysis.
  • A major component of the role involves integrating SOM-generated data with publicly available datasets to benchmark organoid characteristics against normal tissue profiles.
  • The position requires close collaboration with experimental teams to interpret results and guide protocol optimization, as well as contributing to manuscript preparation and presenting findings at scientific conferences.

Required Qualifications

  • Candidates must hold a PhD in bioinformatics, computational biology, biostatistics, or a related quantitative field.
  • Extensive experience with single-cell data analysis, including familiarity with tools such as Seurat, Scanpy, or similar platforms, is essential.
  • Strong programming skills in R and Python are required, along with experience in statistical analysis and data visualization.
  • Knowledge of proteomics and metabolomics data analysis workflows is necessary.

Preferred Qualifications

  • Previous experience analyzing organoid datasets is strongly preferred.
  • Experience with machine learning approaches for biological data, familiarity with pathway analysis tools, and knowledge of developmental biology principles will be considered valuable assets.
  • Experience with high-performance computing environments and version control systems is desirable.

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

The diversity of Axle's employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: careers@axleinfo.com

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate's experience, qualifications, skills, and location.

#INDPSD #IND

Salary Range
$105,000—$120,000 USD