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Single Cell Rna Sequencing Phd Jobs in California

$62K - $63K/yr

Manage and mentor PhD level scientists, set the technical direction for the analytics sub team, and ... A proven track record of applying machine learning to analyze single cell RNA sequencing data to ...

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Single Cell Rna Sequencing Phd information

What is a single cell RNA sequencing PhD?

A Single Cell RNA Sequencing PhD is a doctoral degree focused on the study and application of single-cell RNA sequencing (scRNA-seq) technologies. This field involves analyzing the gene expression profiles of individual cells, allowing researchers to understand cellular heterogeneity and complex biological processes at a granular level. PhD students in this area typically conduct original research, develop computational methods, and advance our understanding of cell biology, disease mechanisms, and potential therapeutic targets. Graduates often pursue careers in academia, biotechnology, or pharmaceutical research.

What is the difference between Single Cell Rna Sequencing Phd vs Single Cell Data Analyst?

AspectSingle Cell Rna Sequencing PhdSingle Cell Data Analyst
Required CredentialsPhD in Biology, Genetics, or related fieldBachelor's or Master's in Data Science, Biology, or related field
Work EnvironmentResearch labs, biotech companies, academic institutionsBiotech firms, research organizations, healthcare companies
Industry UsageDesigning experiments, interpreting sequencing data, publishing researchAnalyzing sequencing datasets, creating reports, data visualization

The Single Cell Rna Sequencing Phd typically involves designing experiments and interpreting complex sequencing data, requiring advanced research skills. In contrast, a Single Cell Data Analyst focuses on analyzing datasets, generating insights, and visualizing data, often with less emphasis on experimental design. Both roles are vital in the biotech industry but differ in their focus and required expertise.

What are some common challenges faced by researchers in a single cell RNA sequencing PhD role, and how can they be addressed?

One of the main challenges in a Single Cell RNA Sequencing PhD role is managing and interpreting large, complex datasets generated from single-cell experiments. Researchers must be proficient in both wet-lab techniques and bioinformatics analysis, often requiring collaboration with computational biologists. Another challenge is ensuring sample quality and minimizing technical variability, which can significantly impact data reliability. Staying updated with rapidly evolving sequencing technologies and analytical tools is crucial, as is developing strong problem-solving skills to troubleshoot experimental or computational issues.

What are the key skills and qualifications needed to thrive as a single cell RNA sequencing PhD, and why are they important?

To thrive as a Single Cell RNA Sequencing PhD, you need a strong background in molecular biology, bioinformatics, and genomics, typically supported by a PhD in a relevant field. Proficiency with single-cell sequencing platforms (e.g., 10x Genomics), next-generation sequencing (NGS) technologies, and computational analysis tools like R or Python is essential. Critical thinking, problem-solving, and effective communication are crucial soft skills for interpreting complex data and collaborating within multidisciplinary teams. These skills and qualifications are vital for designing robust experiments, analyzing high-dimensional data, and translating findings into impactful biological insights.
What job categories do people searching Single Cell Rna Sequencing Phd jobs in California look for? The top searched job categories for Single Cell Rna Sequencing Phd jobs in California are:
What cities in California are hiring for Single Cell Rna Sequencing Phd jobs? Cities in California with the most Single Cell Rna Sequencing Phd job openings:
Infographic showing various Single Cell Rna Sequencing Phd job openings in California as of August 2026, with employment types broken down into 1% Locum Tenens, 70% Full Time, 24% Part Time, 2% Temporary, and 3% Contract. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution.

Junior Specialist - Nowakowski Lab

University of California, San Francisco

San Francisco, CA • On-site

Full-time

Re-posted 11 days ago


University Of California San Francisco rating

7.8

Company rating: 7.8 out of 10

Based on 13 frontline employees who took The Breakroom Quiz

229th of 617 rated colleges and universities


Job description

Application Window
Open date: May 1, 2026
Most recent review date: Saturday, May 16, 2026 at 11:59pm (Pacific Time) Applications received after this date will be reviewed by the search committee if the position has not yet been filled.
Final date: Monday, Nov 1, 2027 at 11:59pm (Pacific Time) Applications will continue to be accepted until this date, but those received after the review date will only be considered if the position has not yet been filled.
Position description
Position Overview
The Nowakowski Lab in the Department of Neurological Surgery at UCSF is seeking a highly motivated and detail-oriented Junior Specialist to join our dynamic, multi-disciplinary research team. This position focuses on modeling neurodevelopmental disorders using human pluripotent stem cells (hPSCs), including induced pluripotent stem cells (iPSCs) and embryonic stem cells (ESCs), to generate brain organoids and other in vitro models of human brain development.
The successful candidate will contribute to cutting-edge research aimed at uncovering the molecular and cellular mechanisms underlying neurodevelopmental and neuropsychiatric conditions-including Autism Spectrum Disorders (ASD), Schizophrenia, and related genetic syndromes such as microdeletion syndromes-by designing, conducting, and analyzing experiments at the intersection of stem cell biology, functional genomics, and developmental neuroscience.
This position offers an exceptional opportunity to work at the forefront of human brain research in a collaborative and innovative environment within the UCSF Weill Institute for Neurosciences.
Research Environment
Key Responsibilities
Stem Cell Culture and Disease Modeling
  • Design and execute experiments involving the culture, maintenance, and differentiation of human pluripotent stem cells
  • Generate, maintain, and characterize brain organoids and multi-region assembloid models for the study of neurodevelopmental disorders
  • Develop and optimize differentiation protocols to derive specific neural cell types of interest, including cortical excitatory neurons, inhibitory interneurons, and glial cells
  • Establish and validate iPSC lines carrying disease-associated mutations for modeling conditions such as ASD

Molecular and Cellular Analysis
  • Perform molecular biology techniques including PCR, RT-qPCR, Western blotting, immunofluorescence staining, and flow cytometry to characterize differentiated cell populations
  • Apply CRISPR/Cas9 genome editing to engineer isogenic cell lines and investigate gene function and regulatory networks in stem cell-derived neural systems
  • Conduct high-throughput screening experiments to identify disease-relevant phenotypes and candidate therapeutic targets
  • Prepare samples for and assist with single-cell RNA sequencing (scRNA-seq) and single-cell ATAC sequencing (scATAC-seq) experiments

Data Analysis, Documentation, and Collaboration
  • Analyze experimental data using statistical methods and contribute to computational analyses in collaboration with bioinformatics team members
  • Maintain meticulous laboratory records and contribute to research publications, grant applications, and presentations
  • Participate in lab meetings, journal clubs, and departmental seminars
  • Assist with laboratory management, including maintaining equipment, ordering supplies, and ensuring compliance with biosafety and ethical protocols

Qualifications
Basic Qualifications
  • Baccalaureate degree (or equivalent degree) in biology, neuroscience, biochemistry, bioengineering, or a related field by the time of hire; OR at least four years of research experience.

Preferred Qualifications
  • Hands-on experience with human pluripotent stem cell (iPSC/ESC) culture, maintenance, and differentiation
  • Familiarity with brain organoid or 3D neural culture systems
  • Proficiency in molecular biology techniques: PCR, Western blotting, immunofluorescence, flow cytometry
  • Experience with CRISPR/Cas9 genome editing and its application in stem cell research
  • Exposure to single-cell genomics workflows (scRNA-seq, scATAC-seq) or willingness to learn
  • Strong organizational skills and meticulous attention to detail in maintaining laboratory records
  • Excellent written and verbal communication skills
  • Ability to work collaboratively in a fast-paced, multi-disciplinary team environment
  • Demonstrated commitment to maintaining a safe and ethical laboratory environment

Application Requirements
Interested candidates should submit the following materials through the UC AP Recruit system:
  1. Cover Letter- Describe your research interests, relevant experience, and motivation for joining the Nowakowski Lab
  2. Curriculum Vitae - Including a list of publications, if applicable
  3. Contact Information for 2-3 References - Letters of recommendation may be requested upon further review

Applicants' materials must list current and/or pending qualifications upon submission. The position will remain open until filled. All qualified applicants are encouraged to apply. Click here to apply .
See Table 24B for the salary range for this position. A reasonable estimate for this position is $55,000 - $58,600.
Application Requirements
Document requirements
  • Curriculum Vitae - CV must clearly list current and/or pending qualifications (e.g. board eligibility/certification, medical licensure, etc.).
    Including a list of publications, if applicable
  • Cover Letter - Describe your research interests, relevant experience, and motivation for joining the Nowakowski Lab.
  • Statement of Research (Optional)
  • Statement of Teaching (Optional)

Reference requirements
  • 2-3 required (contact information only)

About UC San Francisco
As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.
The University of California is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected status under state or federal law.
UCSF is committed to welcoming and serving all people, honoring the dignity of every individual without preference or prejudice, in support of its public mission and in alignment with our PRIDE values and Principles of Community.
As a condition of employment, the finalist will be required to disclose if they are subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct.
• "Misconduct" means any violation of the policies or laws governing conduct at the applicant's previous place of employment, including, but not limited to, violations of policies or laws prohibiting sexual harassment, sexual assault, or other forms of harassment, or discrimination, as defined by the employer.
• UC Sexual Violence and Sexual Harassment Policy
• UC Anti-Discrimination Policy
• APM - 035: Affirmative Action and Nondiscrimination in Employment
Job location
San Francisco, CA

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