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Senior Statistical Programmer Jobs in Cumberland, RI

Vrtx

Principal Statistical Programmer

Boston, MA · Remote

$149K - $223K/yr

The Principal Statistical Programmer works with management to delegate tasks appropriately, track ... Senior Management levels * Creates all files, documents, and analyses necessary to support an ...

Massgeneralbrigham

Biostatistician Principal

Boston, MA · On-site

$56.59 - $82.31/hr

Job Summary The Chai Laboratory seeks a doctoral-level Senior Computational Scientist to provide ... Qualifications Education Master's Degree Statistics required or Master's Degree Related Field of ...

Mass General Brigham

Biostatistician Principal

Boston, MA · On-site

$56.59 - $82.31/hr

Job Summary The Chai Laboratory seeks a doctoral-level Senior Computational Scientist to provide ... Qualifications Education Master's Degree Statistics required or Master's Degree Related Field of ...

Vrtx

Analytics CoE Senior Manager

Boston, MA · On-site

$144K - $216K/yr

The Senior Manager Director role is within HEOR's Analytics Center of Excellence (CoE), a ... This role will work closely with a team of statistical programmers to lead the execution of data ...

Vrtx

Sr. Biostatistician II

Boston, MA · Hybrid

$132K - $198K/yr

The Senior Biostatistician II will perform scientific statistical analyses in support of the ... Collaborates with statistical programming and other functions to ensure timely delivery of TFLs ...

Vertex Pharmaceuticals

Sr. Biostatistician II

Boston, MA · On-site

$132K - $198K/yr

The Senior Biostatistician II will perform scientific statistical analyses in support of the ... Collaborates with statistical programming and other functions to ensure timely delivery of TFLs ...

Vrtx

Senior Biostatistician II

Boston, MA · Hybrid

$132K - $198K/yr

The Senior Biostatistician II will perform scientific statistical analyses in support of the ... Collaborates with statistical programming and other functions to ensure timely delivery of TFLs ...

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All JobsStatistical Programmer JobsSenior Statistical Programmer JobsSenior Statistical Programmer Jobs in Cumberland, RI

Senior Statistical Programmer information

See Cumberland, RI salary details

$73.5K

$114.3K

$149.3K

How much do senior statistical programmer jobs pay per year?

As of Aug 30, 2026, the average yearly pay for senior statistical programmer in Cumberland, RI is $114,339.00, according to ZipRecruiter salary data. Most workers in this role earn between $95,400.00 and $131,900.00 per year, depending on experience, location, and employer.

What is a senior statistical programmer?

A Senior Statistical Programmer is responsible for developing, testing, and validating statistical programs used for clinical trial data analysis. They work primarily with statistical software like SAS to generate tables, listings, and figures (TLFs) for regulatory submissions and research studies. This role requires strong programming skills, knowledge of statistical methodologies, and an understanding of clinical trial processes. Senior Statistical Programmers also collaborate with statisticians, data managers, and regulatory teams to ensure data integrity and compliance with industry standards.

What are the typical responsibilities and team dynamics for a senior statistical programmer?

As a Senior Statistical Programmer, you will typically be responsible for designing, developing, and validating statistical programs for clinical trial data analysis and reporting. You’ll work closely with biostatisticians, data managers, and clinical project teams to ensure data quality and regulatory compliance, often contributing to the creation of submission datasets and study reports. The role usually involves both independent work and active collaboration, with seasoned programmers frequently mentoring junior staff and participating in process improvement initiatives. This team-oriented structure offers exposure to a variety of projects and stakeholders, making it a dynamic environment ideal for those who enjoy both analytical tasks and cross-functional teamwork.

What are the key skills and qualifications needed to thrive as a senior statistical programmer, and why are they important?

To thrive as a Senior Statistical Programmer, a strong background in statistical analysis, programming (often in SAS and R), and a relevant degree such as in statistics, mathematics, or computer science is essential. Experience with regulatory submission standards (like CDISC SDTM/ADaM), clinical trial software, and certifications such as SAS Certified Advanced Programmer are highly valued. Outstanding attention to detail, problem-solving abilities, and effective communication skills help individuals excel in this collaborative and deadline-driven role. These skills are crucial for ensuring accurate data analysis, regulatory compliance, and successful teamwork in high-stakes research environments.

Senior Statistical Programmer jobs near you
Infographic showing various Senior Statistical Programmer job openings in Cumberland, RI as of August 2026, with employment types broken down into 1% Internship, 75% Full Time, 21% Part Time, 2% Contract, and 1% Nights. Highlights an 79% Physical, 3% Hybrid, and 18% Remote job distribution, with an average salary of $114,339 per year, or $55 per hour.

Principal Statistical Programmer

Boston, MA • Remote

Vrtx
See more jobs at Vrtxexternal

$149K - $223K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 4 days ago

Job description

Job Description

General Summary:

The Principal Statistical Programmer works with management to delegate tasks appropriately, track progress, and provide expert technical support to team members. In addition, the Principal Statistical Programmer is a designated member of clinical sub-team(s) in the role of project lead Statistical Programmer.

Key Duties and Responsibilities:

  • Works regularly with advanced features of SAS (including interfacing ability with other software applications and operating system tools)

  • Performs quality control checks of SAS code and output produced by other Statistical Programmers to ensure accuracy and consistency within group

  • Demonstrates in-depth knowledge of clinical development and medical data

  • Solves complex clinical trial reporting problems and demonstrates technical proficiency and exercises judgment in supporting daily operations and ensuring that study tasks are completed accurately and in a timely manner

  • Engages with a variety of other functions, including Statistical Programmers, Biostatisticians, Data Management, and other departments engaged in providing data and submission-related activities, often at Senior Management levels

  • Creates all files, documents, and analyses necessary to support an electronic submission in eCTD format, including ISS/ISE

  • Provides leadership to ensure compliance with Vertex SOP'S and FDA/ICH/GCP regulations

  • Provides technical and project management skills to create, review, and approve documentation required to support data analysis, reporting, and CDlSC data submission

  • Participates in project management cross-functional teams that work on standard operating procedures, guidelines, process improvements, system validation and acquisition, customization, and integration of new tools and technologies

Knowledge and Skills:

  • Proficiency in all SAS language, procedures, and functions commonly used in clinical trial reporting including the Macro language, BASE SAS, SAS/STAT and SAS/GRAPH

  • Intermediate knowledge of CDISC Standards

  • Intermediate knowledge of clinical trials

  • Regulatory submission experiences

  • Effective communication (written and verbal) skills to explain difficult information

Education and Experience:

  • Bachelors degree in a Scientific Discipline

  • Typically requires 5+ for M.S. or above and 8+ years for B.S. years of work experience in Biotech, Pharmaceuticals or Clinical Research Organization

Pay Range:

$149,200 - $223,800

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Remote-Eligible

Flex Eligibility Status:

In this Remote-Eligible role, you can choose to be designated as:
1. Remote: work remotely five days per week and come into the office on occasion - you're always welcome on-site; or select
2. Hybrid: work remotely up to two days per week; or select
3. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Remote

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

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