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Senior Software Engineer Node Js Jobs in Charleston, SC

PEMCCO, Inc.

Senior Software Engineer

Hanahan, SC · On-site

$53.35 - $88.03/hr

PEMCCO is seeking a Senior Software Engineer to provide technical leadership in the design, development, integration, testing, and sustainment of software applications and systems supporting critical ...

PEMCCO

Senior Software Engineer

Hanahan, SC · On-site

$73.49 - $121.27/hr

PEMCCO is seeking a Senior Software Engineer to provide technical leadership in the design, development, integration, testing, and sustainment of software applications and systems supporting critical ...

PEMCCO, Inc.

Senior Software Engineer

Hanahan, SC · On-site

$53.35 - $88.03/hr

PEMCCO is seeking a Senior Software Engineer to provide technical leadership in the design, development, integration, testing, and sustainment of software applications and systems supporting critical ...

PEMCCO

Senior Software Engineer

Hanahan, SC · On-site

$53.35 - $88.03/hr

PEMCCO is seeking a Senior Software Engineer to provide technical leadership in the design, development, integration, testing, and sustainment of software applications and systems supporting critical ...

Benefitfocus

Sr. Software Engineer

Charleston, SC · On-site

$116K - $153K/yr

Senior Software Engineer This Senior Software Engineer will be responsible for full cycle development of our Account Services program. The Engineer will work closely with the Enterprise Architect ...

Benefitfocus

Sr. Software Engineer

Charleston, SC · On-site

$116K - $153K/yr

Senior Software Engineer This Senior Software Engineer will be responsible for full cycle development of our Account Services program. The Engineer will work closely with the Enterprise Architect ...

DAS Technology Group

Senior Software Engineer

Charleston, SC · On-site

$114K - $151K/yr

Senior Software Engineer/ Software Engineer IV Department: Design Engineering Overview: We are seeking an experienced Software Engineer to join our team. In this role you will design, develop, test ...

Worky

Senior Software Engineer IV

Hollywood, SC · On-site

$120 - $150/hr

The Senior Software Engineer IV will own architecture, design, and engineering of core STARLIMS software building user-facing applications, business rules, data management logic, and embedded system ...

DAS Technology Group

Senior Software Engineer

Charleston, SC · On-site

$114K - $151K/yr

DAS Technology Group is seeking an experienced Software Engineer to join their team. In this role, you will design, develop, test, and maintain software systems and applications, collaborating with ...

Ignite Digital

Embedded Software Engineer

Charleston, SC · On-site

$123K - $161K/yr

The ideal candidate is a hands-on engineer who is equally comfortable developing software ... node devices, ensuring the software developed integrates into the hardware components, and ...

New

PEMCCO, Inc.

Lead Software Developer

Hanahan, SC · On-site

$36.43 - $54.64/hr

Ability to obtain and maintain a government security clearance if required Are you a senior ... PEMCCO is seeking a Lead Software Developer to develop, enhance, and maintain complex software ...

PEMCCO, Inc.

Lead Software Developer

Hanahan, SC · On-site

$36.43 - $54.64/hr

Ability to obtain and maintain a government security clearance if required Are you a senior ... PEMCCO is seeking a Lead Software Developer to develop, enhance, and maintain complex software ...

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All JobsSoftware Engineer Node Js JobsSenior Software Engineer Node Js JobsSenior Software Engineer Node Js Jobs in Charleston, SC

Senior Software Engineer Node Js information

See Charleston, SC salary details

$80.5K

$135.5K

$168.9K

How much do senior software engineer node js jobs pay per year?

As of Aug 23, 2026, the average yearly pay for senior software engineer node js in Charleston, SC is $135,544.00, according to ZipRecruiter salary data. Most workers in this role earn between $121,700.00 and $151,600.00 per year, depending on experience, location, and employer.

What is the difference between Senior Software Engineer Node Js vs Software Developer Node Js?

AspectSenior Software Engineer Node JsSoftware Developer Node Js
Required CredentialsBachelor's degree in CS or related field, 5+ years experience, advanced knowledge of Node JsBachelor's degree in CS or related field, 1-3 years experience, foundational Node Js skills
Work EnvironmentLead projects, mentor junior staff, collaborate with cross-functional teamsDevelop features, fix bugs, implement new functionalities under supervision
Employer & Industry UsageTech companies, startups, enterprise software teamsStartups, small to medium tech firms, freelance projects

The main difference between a Senior Software Engineer Node Js and a Software Developer Node Js lies in experience, responsibilities, and leadership. Senior engineers typically lead projects and mentor others, while developers focus on coding and task execution. Both roles require strong Node Js skills, but senior roles demand more experience and strategic input.

What are popular job titles related to Senior Software Engineer Node Js jobs in Charleston, SC?

For Senior Software Engineer Node Js jobs in Charleston, SC, the most frequently searched job titles are:

What job categories do people searching Senior Software Engineer Node Js jobs in Charleston, SC look for?

The top searched job categories for Senior Software Engineer Node Js jobs in Charleston, SC are:

What cities near Charleston, SC are hiring for Senior Software Engineer Node Js jobs?

Cities near Charleston, SC with the most Senior Software Engineer Node Js job openings:

Senior Software Engineer Node Js jobs near you
Infographic showing various Senior Software Engineer Node Js job openings in Charleston, SC as of August 2026, with employment types broken down into 56% Full Time, and 44% Contract. Highlights an 100% In-person job distribution, with an average salary of $135,544 per year, or $65.2 per hour.

Senior Software Engineer

Charles River Laboratories, Inc.

Charleston, SC

$128K - $133K/yr

Full-time

Medical, Retirement, PTO

Posted 3 days ago

New

Charles River Laboratories rating

8.4

Company rating: 8.4 out of 10

Based on 94 frontline employees who took The Breakroom Quiz

22nd of 86 rated pharmaceutical

Job description

For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

Job Overview

The Senior Software Engineer serves as a technical lead role and is responsible for developing the design and architecture of the interaction between various subsystems and applications. This position is a combination ofadvisory and hands-on involvement on unique custom software development projects for both internal and commercial projects. The senior software engineer will work in conjunction with our System Integration and Software Development teams, responsible to build, improve key features that are integral to our customers,enhance architecture, design, scalability and performance of our existing and new platforms. Extensive knowledgeof .NET, C#, and React.js, PostgreSQL database is critical for the success of the senior software engineer.


Essential Duties and Responsibilities:
•Design, develop, test, deploy, maintain, and enhance the internal and commercial software that controls and automates laboratory devices.
•Conduct and participate in design, code, and test reviews
•Participate in all phases of existing/new software development, including system requirement specification,design, implementation, software integration and testing.
•Prepare appropriate documentation as required by internal product development processes and regulatory agencies (FDA and ISO regulations)

Qualifications

Education:
•Bachelor’s Degree in Computer Science or equivalent Engineering skillset and work experience in SoftwareEngineering
Experience:
•5 years of extensive programming experience, including .NET/ASP.NET, C#, Python and GIT experience is required.
•Understanding of how to translate complex systems into sub-components and optimizing the design of both.
•Experience in a regulated software development environment is desirable.
•Experience with cloud programming like Azure/AWS is desirable.
•Knowledge of continuous integration system (Azure DevOps) to automate application builds, testing, anddeployments to web servers, is optional
Skills and Abilities:
•Excellent critical systems integration thinking, attention to detail, ability to prioritize and work on multiple projectsin a fast-paced, changing environment
•Highly motivated self-starter with a desire to help others and act
•Possess a strong communication skill, including written, verbal and presentation in English
•Knowledge in open-source software engineering

The pay range for this position is $128,000-$133,000. Please note that salaries vary within the range based onfactors including, but not limited to, experience, skills, education, certifications, and location.

About Microbial Solutions
Our Microbial Solutions business group has a comprehensive portfolio of endotoxin testing, microbial detection and microbial identification products and services is unlike any other, and has been purposefully designed to meet the complex and ever-changing needs of the industry. We help clients to ensure product safety and quality with easy-to-use yet robust testing solutions that satisfy regulatory requirements, support critical decision making and improve operational efficiencies.


About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

With over 20,000 employees within 110 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2019, revenue increased to $2.62 billion.

At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of 80% of the drugs approved by the FDA in the last five years.

We’re committed to providing benefits that elevate your quality of life.  Based on your position these may include:  bonus/incentives based on performance, 401K, paid time off, stock purchase program, Health and wellness coverage, employee and family wellbeing support programs, and work life balance flexibility.

Equal Employment Opportunity
Charles River Laboratories is an Equal Opportunity Employer - all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, or national origin, veteran or disability status.

It is unlawful in some states (including Massachusetts) to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to crrecruitment_US@crl.com. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.

For more information, please visit www.criver.com.

What Charles River Laboratories employees say

Pay

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About Charles River

Sourced by ZipRecruiter

Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients' clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market. With over 20,000 employees within 110 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client's unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. At Charles River, we are passionate about our role in improving the quality of people's lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of 86% of the drugs approved by the FDA in 2021.

Industry

Scientific research and development services

Company size

10,000+ Employees

Headquarters location

Wilmington, MA, US

Year founded

1947

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