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Senior Scientist Downstream Process Development Jobs in Delaware

Coherent Corp.

Staff Engineer, Process

Newark, DE · On-site

... Science, Ceramic Engineering, Manufacturing Engineering, or a related discipline * 2-5 years of engineering, manufacturing, process development, or related experience * Manufacturing, process ...

Syner-G

Sr. Process Engineer

Newark, DE

$101K - $131K/yr

The Senior Process Engineer will support technology transfer from development to commercial manufacturing, troubleshoot complex process and yield issues, and provide technical leadership during PPQ ...

Zimmer, Inc.

Manufacturing Sr Engineer I

Wilmington, DE · On-site

$88K - $120K/yr

What You Can Expect The senior manufacturing engineer is responsible for providing manufacturing ... Engineering services may include cell management, process development, project management, process ...

Zimmer, Inc.

Manufacturing Sr Engineer I

Seaford, DE · On-site

$85K - $117K/yr

What You Can Expect The senior manufacturing engineer is responsible for providing manufacturing ... Engineering services may include cell management, process development, project management, process ...

Zimmer, Inc.

Manufacturing Sr Engineer I

Claymont, DE · On-site

$88K - $121K/yr

What You Can Expect The senior manufacturing engineer is responsible for providing manufacturing ... Engineering services may include cell management, process development, project management, process ...

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Senior Scientist Downstream Process Development information

What does a Senior Scientist in Downstream Process Development do?

A Senior Scientist in Downstream Process Development focuses on developing, optimizing, and scaling up processes to purify biological products such as proteins or antibodies after cell culture (the 'downstream' part of biomanufacturing). They design experiments, analyze data, and work with cross-functional teams to ensure product quality and regulatory compliance. Their role is critical in moving biopharmaceutical products from research to commercial production by ensuring efficient and robust purification processes.

What are the key skills and qualifications needed to thrive as a Senior Scientist in Downstream Process Development, and why are they important?

To thrive as a Senior Scientist in Downstream Process Development, you need advanced knowledge in bioprocess engineering, protein purification, and process scale-up, typically supported by a Ph.D. or Master’s degree in a relevant field. Expertise with chromatography systems (such as AKTA), analytical instrumentation, and familiarity with regulatory requirements like GMP are essential. Strong problem-solving abilities, leadership, and effective communication skills distinguish top performers in this role. These competencies are crucial for developing robust, scalable processes that meet quality standards and drive successful product development.

What are some common challenges faced by Senior Scientists in Downstream Process Development, and how can they be addressed?

Senior Scientists in Downstream Process Development often encounter challenges such as optimizing purification processes for novel biologics, scaling up from lab to production scale, and ensuring product consistency and regulatory compliance. Addressing these challenges typically involves close collaboration with cross-functional teams, continuous process optimization, and staying current with industry advancements in chromatography and filtration technologies. Proactive problem-solving, effective communication, and leveraging data analytics are also key strategies for overcoming obstacles in this role.
What are popular job titles related to Senior Scientist Downstream Process Development jobs in Delaware? For Senior Scientist Downstream Process Development jobs in Delaware, the most frequently searched job titles are:
What job categories do people searching Senior Scientist Downstream Process Development jobs in Delaware look for? The top searched job categories for Senior Scientist Downstream Process Development jobs in Delaware are:
Senior Scientist Downstream Process Development jobs near you
Infographic showing various Senior Scientist Downstream Process Development job openings in Delaware as of July 2026, with employment types broken down into 1% As Needed, 83% Full Time, 14% Part Time, and 2% Contract. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution.
Staff Engineer, Process

Staff Engineer, Process

Coherent Corp.

Newark, DE • On-site

Full-time

Posted 3 days ago

Job description


Primary Duties & Responsibilities
  • Partner with operators, production supervisors, engineers, and R&D teams to improve manufacturing processes and product quality
  • Spend significant time on the production floor observing processes, troubleshooting issues, and identifying improvement opportunities
  • Lead and support process improvement projects focused on yield improvement, scrap reduction, throughput, and quality
  • Investigate process and product issues using structured problem-solving techniques and data-driven decision making
  • Develop and execute experiments to better understand process behavior and improve manufacturing performance
  • Support the transfer of manufacturing processes between facilities and help ensure successful implementation across sites
  • Build expertise in ceramic forming processes, thermal processing, and advanced materials manufacturing
  • Document process improvements and support the development of manufacturing procedures and best practices
  • Collaborate with cross-functional teams to introduce new products and technologies into manufacturing
  • Take ownership of projects from problem identification through implementation and follow-up

What success looks like
  • Successfully contribute to one or more process transfer initiatives
  • Deliver measurable improvements in yield, scrap reduction, throughput, or process capability
  • Develop a strong understanding of ceramic forming and thermal processing fundamentals
  • Become a trusted resource for operators, supervisors, and engineering colleagues
  • Demonstrate independent ownership of projects and deliver results

Education & Experience
  • Bachelor's degree in Mechanical Engineering, Chemical Engineering, Materials Science, Ceramic Engineering, Manufacturing Engineering, or a related discipline
  • 2-5 years of engineering, manufacturing, process development, or related experience
  • Manufacturing, process engineering, internship, or co-op experience preferred

Skills & Other Requirements
Strong analytical and problem-solving skills
• Excellent communication and collaboration skills
• Demonstrated ability to work independently while knowing when to seek input from others
• Experience with data analysis, DOE, SPC, Lean Manufacturing, or Six Sigma methodologies preferred
• Experience working in a production environment preferred
• Exposure to materials processing, thermal processing, or advanced manufacturing technologies preferred
• Naturally curious and enjoys understanding how things work
• Comfortable learning through experimentation and hands-on problem solving
• Takes ownership and follows through on commitments
• Prefers solving problems at the source rather than from behind a desk
• Willing to challenge assumptions respectfully when data or observations suggest a better approach
• Enjoys working as part of a team and building strong relationships across functions
Bonus Qualifications
Evidence of hands-on interests and a passion for building, making, repairing, or improving things, such as:
  • Woodworking
  • Automotive projects
  • Robotics
  • Fabrication
  • Machining
  • 3D printing
  • Competitive engineering teams
  • Personal technical projects

Working Conditions
Office and manufacturing floor environment with regular interaction with production processes and equipment.
Physical Requirements
• Ability to occasionally lift/push/pull up to 20 lbs.
• Able to sit, stand, bend, squat and walk about the facility.
• Ability to work safely around manufacturing equipment
Safety Requirements
All employees are required to attend scheduled training, follow the site EHS procedures and Corporate EHS standards. This includes the use of proper protective equipment (PPE) as required by the job responsibilities.
Managers will ensure that all safety and environmental procedures are followed consistently. They will ensure that risk assessments are performed, proper training, work instructions, required PPE is available, and will monitor compliance.
Quality & Environmental Responsibilities
Depending on location, this position may be responsible for the execution and maintenance of the ISO 9000, 9001, 14001 and/or other applicable standards that may apply to the relevant roles and responsibilities within the Quality Management System and Environmental Management System.
Culture Commitment
Ensure adherence to company's values (ICARE) in all aspects of your position at Coherent:
Integrity - Create an Environment of Trust
Collaboration - Innovate Through the Sharing of Ideas
Accountability - Own the Process and the Outcome
Respect - Recognize the Value in Everyone
Enthusiasm - Find a Sense of Purpose in Work
Coherent Corp. is an equal opportunity/affirmative action employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law.
If you need assistance or an accommodation due to a disability, you may contact us at talentacquisition@coherent.com.
About Us
Coherent is a global leader in lasers, engineered materials and networking components. We are a vertically integrated manufacturing company that develops innovative products for diversified applications in the industrial, optical communications, military, life sciences, semiconductor equipment, and consumer markets. Coherent provides a comprehensive career development platform within an environment that challenges employees to perform at their best, while rewarding excellence and hard-work through a competitive compensation program. It's an exciting opportunity to work for a company that offers stability, longevity and growth. Come Join Us!
Note to recruiters and employment agencies: We will not pay for unsolicited resumes from recruiters and employment agencies unless we have a signed agreement and have required assistance, in writing, for a specific opening.

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