1

Senior Python Startup Jobs in South Carolina (NOW HIRING)

MANTX -- JUNIOR SOFTWARE DEVELOPER Mantx is a fast-growing software startup building a modern ... senior engineers - Ship user-facing UI in Vue 3 + Vuetify - Develop API endpoints in Python ...

Sr. DevOps Engineer

Charleston, SC · On-site

$121K - $156K/yr

Remote, US Based JOB SUMMARY We are a next-generation AI-powered MarTech and AdTech startup on a ... Python/Bash) and automation tools. Infrastructure & Reliability * Infrastructure as Code (IaC)

We are currently seeking a Professional Services Engineer, reporting to the Sr. Manager of ... US Citizen * 5+ years of experience in cybersecurity (Prior startup experience preferred)

... high-growth startup. This is a remote-first role with occasional (~1x month) travel ... for senior leadership and stakeholders * Work cross-functionally with commercial, analytics ...

... high-growth startup. This is a remote-first role with occasional (~1x month) travel ... for senior leadership and stakeholders * Work cross-functionally with commercial, analytics ...

... high-growth startup. This is a remote-first role with occasional (~1x month) travel ... for senior leadership and stakeholders * Work cross-functionally with commercial, analytics ...

... high-growth startup. This is a remote-first role with occasional (~1x month) travel ... for senior leadership and stakeholders * Work cross-functionally with commercial, analytics ...

Senior Python Startup information

What is the difference between Senior Python Startup vs Python Developer?

AspectSenior Python StartupPython Developer
CredentialsBachelor's or higher in CS, experience in startupsBachelor's in CS or related field, some experience
Work EnvironmentFast-paced startup, cross-functional teamsEstablished companies or startups, team-based
Industry UsageTech startups, innovative projectsVaried industries, software development
Search IntentSenior roles, startup environment, advanced skillsEntry to mid-level roles, Python programming

Senior Python Startup roles typically require more experience, leadership skills, and familiarity with startup environments. Python Developers may have similar technical skills but often at an earlier career stage and in more established settings. The main difference lies in experience level and work context, with Senior Python Startup positions emphasizing leadership and startup agility.

What are the most commonly searched types of Python Startup jobs in South Carolina?

The most popular types of Python Startup jobs in South Carolina are:

What job categories do people searching Senior Python Startup jobs in South Carolina look for?

The top searched job categories for Senior Python Startup jobs in South Carolina are:

What cities in South Carolina are hiring for Senior Python Startup jobs?

Cities in South Carolina with the most Senior Python Startup job openings:

Senior Full-Stack Software Engineer

DealerCopilot

Charleston, SC • On-site

Full-time

Re-posted 8 days ago


Job description

Job Summary:
DealerCopilot is an early-stage AI company focused on enhancing dealership operations. They are seeking a Senior Full-Stack Software Engineer to own end-to-end feature development, lead architectural decisions, and collaborate closely with the technical co-founder.
Responsibilities:
• Own end-to-end feature development across our full stack: React frontends, C#/.NET and Python backends, and AWS cloud infrastructure
• Lead architecture and data modeling decisions across PostgreSQL, MongoDB, and vector storage
• Design and build integrations with third-party automotive APIs and dealership management systems (CDK, Fortellis, OEM APIs)
• Operate AI-first: leverage agentic coding tools (Claude Code, Cursor, Copilot) as a core multiplier in your daily workflow
• Set engineering standards — code review, testing practices, CI/CD, observability — as the senior technical voice on the team
• Collaborate directly with the technical co-founder on technical strategy, architecture reviews, and roadmap prioritization
• Mentor and eventually manage junior engineers as the team scales
Qualifications:
Required:
• 4+ years of professional full-stack software engineering experience
• Strong proficiency with React or a modern frontend framework
• Deep experience with at least one compiled server-side language — C#/.NET preferred
• Production-grade experience with both relational (PostgreSQL, SQL Server) and document (MongoDB) databases
• Demonstrated use of AI-assisted and agentic coding tools as a core part of your workflow — not just familiarity
• Experience designing and owning systems end-to-end: schema design, API design, deployment, and observability
• Strong fundamentals: distributed systems, concurrency, performance optimization, and software design patterns
Preferred:
• Hands-on AWS experience: ECS/Fargate, Lambda, RDS, CloudWatch, CloudFormation
• Python experience for scripting, data pipelines, or ML/AI workflows
• CI/CD, Docker, and infrastructure-as-code experience
• Exposure to the automotive industry, DMS systems, or B2B SaaS in a vertical market
• Experience at an early-stage startup or founding engineering role
Company:
DealerCopilot deploys role-based AI agents that execute best-practice workflows consistently and autonomously — driving ROI, productivity, and a better customer experience across your entire operation. Founded in 2026, the company is headquartered in Charleston, USA, with a team of 11-50 employees. The company is currently Early Stage.