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Senior Python Engineer Jobs in Lancaster, PA (NOW HIRING)

Senior Modeling Engineer

York, PA · On-site +1

$102K - $141K/yr

... Senior Modeling Engineer. As a member of the modeling team, you will develop and apply numerical ... Python scripting and environment management (package installation, virtual environments, basic ...

Senior BI Engineer, Data

Lititz, PA · On-site +1

$98K - $133K/yr

As a Senior BI Engineer , you will architect and own the next generation of our enterprise data ... Develop Python based ingestion utilities, automation scripts, and reusable components. * Establish ...

Develop analytics solutions using Python and PySpark * Support data pipeline design, validation ... Collaborate with data science, engineering, and reporting teams to deliver standardized data ...

Develop analytics solutions using Python and PySpark * Support data pipeline design, validation ... Collaborate with data science, engineering, and reporting teams to deliver standardized data ...

Develop analytics solutions using Python and PySpark * Support data pipeline design, validation ... Collaborate with data science, engineering, and reporting teams to deliver standardized data ...

Sr. Embedded Coder

Harrisburg, PA · On-site

$128K - $192K/yr

Programming Arm Cortex microcontrollers * Programming 16-bit PIC microcontrollers * Serial ... Support SW using LabView, python, Excel, and Matlab/Octave Team Composition/Specific Group Info You ...

Work with senior technical staff in developing system architectures for the future PTZ platforms ... Common coding languages such as Python/C++ for test development & Linux OS * Global compliance ...

Work with senior technical staff in developing system architectures for the future PTZ platforms ... Common coding languages such as Python/C++ for test development & Linux OS * Global compliance ...

Work with senior technical staff in developing system architectures for the future PTZ platforms ... Common coding languages such as Python/C++ for test development & Linux OS * Global compliance ...

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Showing results 1-20

Senior Python Engineer information

See Lancaster, PA salary details

$53.5K

$138K

$189.5K

How much do senior python engineer jobs pay per year?

As of Jul 29, 2026, the average yearly pay for senior python engineer in Lancaster, PA is $137,978.00, according to ZipRecruiter salary data. Most workers in this role earn between $118,100.00 and $158,900.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Senior Python Engineer, and why are they important?

To thrive as a Senior Python Engineer, you need expert knowledge of Python programming, software architecture, and experience with web frameworks, supported by a degree in computer science or related field. Familiarity with tools like Django, Flask, REST APIs, Docker, and version control systems such as Git is typically required, along with possible certifications in cloud technologies or Python itself. Strong problem-solving abilities, leadership, and effective communication skills help you lead teams and collaborate across departments. These skills ensure robust, scalable software solutions and foster innovation and efficiency within development projects.

What does a Senior Python Engineer do?

A Senior Python Engineer is an experienced software developer who specializes in designing, developing, and maintaining applications using the Python programming language. They often take on leadership roles within development teams, contribute to architectural decisions, and mentor junior engineers. Senior Python Engineers work on complex projects, ensure code quality, and help implement best practices to improve efficiency and reliability. Their work may span back-end development, data engineering, automation, and integrating with other technologies.

What are the common challenges Senior Python Engineers face when leading projects, and how can they effectively address them?

Senior Python Engineers often encounter challenges such as balancing hands-on coding with overseeing project architecture, mentoring junior developers, and ensuring code quality across the team. Effectively addressing these challenges involves strong communication, setting clear coding standards, and fostering a collaborative environment through regular code reviews and knowledge-sharing sessions. Staying updated on best practices and leveraging automation tools for testing and deployment can also help streamline workflows and maintain high-quality deliverables.
What are popular job titles related to Senior Python Engineer jobs in Lancaster, PA? For Senior Python Engineer jobs in Lancaster, PA, the most frequently searched job titles are:
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What cities near Lancaster, PA are hiring for Senior Python Engineer jobs? Cities near Lancaster, PA with the most Senior Python Engineer job openings:
Asset Management Senior Engineer

Asset Management Senior Engineer

GlaxoSmithKline

Marietta, PA

$98K - $135K/yr

Full-time

Posted 24 days ago


GlaxoSmithKline rating

8.9

Company rating: 8.9 out of 10

Based on 19 frontline employees who took The Breakroom Quiz

9th of 86 rated pharmaceutical


Job description

Are you looking for an engineering role that allows you to leverage your technical knowledge in a state-of-the-art manufacturing environment? If so, this Asset Management Senior Engineer role could be an ideal opportunity to explore.

The operational asset management specialist plays a key role in helping manufacturing sites reliably deliver products to patients by improving how physical assets are managed and operated. Working closely with site teams, he supports the deployment of asset management standards across work management, operational reliability and reliability by design, calibration management, and engineering store management. His contribution increases asset availability, reduce operational losses, and embed compliant, datadriven ways of working. Through handson collaboration at site level and effective use of EAM systems and digital tools, he enables sites to secure service to patients, improves cost management and asset usage while maintaining the highest standards of Quality, EHS, and GMP compliance.

This role is practical and impactfocused: He helps turn standards into daily operational practices that create measurable and sustainable value for the business.

Each specialist is expected to master a combination of 2 of the first 4 domains and brings a demonstrated level of competencies in the 4th level, supporting their primary 2 specialties.

1. Reliability Excellence Management

  • Master asset reliability standards: FMECA, RCM, RAMS, Preventive maintenance effectiveness review, preventive maintenance optimization, root cause analysis, bad actor management, and criticality management.

  • Have a good knowledge of supportive EHS tools including Hazid, Hazop and LOA.

  • Use EAM data (SAP ECC, S/4HANA, ...) to drive improvements

  • Optimize reliability strategies reducing failure rate, and optimization costs

  • Oversight GMP and EHS compliance across sites and support implementation of actions.

  • Work handson with site teams to convert reliability analysis into sustained actions.

  • Leverage digital solutions (ex. Python) to improve diagnostics and decisionmaking.

  • Use cross sites scorecards to enable benchmarking across sites.

  • Animate the reliability engineering COP, ensuring consistent development of site engineers.

2. Work Execution Management

  • Master endtoend work management processes: gatekeeping, planning, scheduling, preparation, execution, and work order closure.

  • Ensure consistent/quality CMMS data to enable effective planning and execution.

  • Support sites in improving daily maintenance execution, reducing emergency work, backlog, and asset impact, with strong collaboration with the GPS team.

  • Promote disciplined use paperless tools, in compliance with data integrity requirements.

  • Drive measurable improvements in asset availability, productivity, and cost efficiency through better work management practices, cross site scorecard.

  • Animate the work management CoP, ensuring consistence development of site engineers.

3. Calibration Management

  • Master calibration management processes from regulatory requirements to execution and audit readiness, ensuring coherence between calibration specifications, process requirements, and maintenance plans.

  • Structure and maintain calibration data in SAP/EAM (assets, plans, cycles, tolerances, priorities) with strong data integrity. Work closely with the CMMS groups to ensure consistency across systems and get the data needed to drive continuous improvement.

  • Identify opportunities to optimize calibration strategies based on risk, performance, and regulatory expectations, delivering data driven calibration optimization insights

  • Work closely with Quality, Engineering, and Maintenance teams to ensure compliant and efficient calibration execution. Contribute to the reliability governance as lead to animate the calibration community of practices.

  • Use digital tools and AI to enable metrics and insights, accelerating decision making & simplification of data analysis, consistency across all manufacturing groups.

4. Engineering stores

  • Master engineering stores and spare parts management processes, including critical spares, stock strategies, and obsolescence management.

  • Align CMMS equipment structures, BOMs, spare parts, and maintenance plans.

  • Optimize inventory levels, cash exposure, and risk while increasing parts availability.

  • Link reliability analysis with spare parts strategies to reduce MTTR, prevent failures.

  • Use CMSS data and digital tools (AI, Python, etc.) to deliver insights driving actions.

  • Animate engineering stores COP driving continuous improvement and capabilities development across all sites. Use scorecards & insights to drive cross site benchmarks.

5. Stakeholder Engagement & Collaboration

  • Acted as a single point of contact for site Engineering teams and operational leads in his field of specialties.

  • Leverage GSK production system to eliminate waste and failures, improve continuously.

  • Built relationships with sites, service providers or stakeholders aligned with objectives.

6. Digital fluency

  • Contribute to translating Business processes into functional requirements, working closely with the operational engineering system director.

  • Ensuring reporting tool supports business needs in his field of competency. Regularly assess tool features against enterprise needs.

  • Ability to manipulate databases and use SQL to query data. Using Python is a plus.

Why you?Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

  • Bachelor's degree in mechanical, Electrical, Automation or Chemical Engineering

  • Orange Belt

  • 5+ years' experience working in a highly regulated Good Manufacturing Practices (GMP) environment

  • Experience leading facility equipment programs and leading maintenance teams

  • experience with machines, production lines, and working in highly regulated environments such as pharma, healthcare, food, cosmetics, or aeronautics.

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

  • Masters degree in mechanical, Electrical, Automation or Chemical Engineering

  • 5+ years of experience in the pharmaceutical industry

  • Green Belt

  • Leadership experience in coaching and collaborative working

  • Familiarity with manufacturing regulatory requirements

  • Strong written and verbal communications skills

  • Ability to influence at all levels

  • Proven ability to manage diverse stakeholder groups, including Senior Management.

  • Education: Master of Engineering (Global Maintenance & Reliability preferred or demonstrated experience)

  • Skills: Networking, influencing, analytical thinking, and strong communication abilities.

    Why GSK?

    Our values and expectationsare at the heart of everything we do and form an important part of our culture.

    These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities:

    • Agile and distributed decision-making - using evidence and applying judgement to balance pace, rigour and risk

    • Managing individual and team performance.

    • Committed to delivering high quality results, overcoming challenges, focusing on what matters, execution.

    • Implementing change initiatives and leading change.

    • Sustaining energy and well-being, building resilience in teams.

    • Continuously looking for opportunities to learn, build skills and share learning both internally and externally.

    • Developing people and building a talent pipeline.

    • Translating strategy into action - a compelling narrative, motivating others, setting objectives and delegation.

    • Building strong relationships and collaboration, managing trusted stakeholder relationships internally and externally.

    • Budgeting and forecasting, commercial and financial acumen.

    About the Zebulon Site

    GSK's Zebulon site is a global supplier of Respiratory and Solid Dose medicines to patients around the globe and the largestGSKPharmaceuticalsecondary manufacturing site in North America. The site islocatedless than 30 minutes from downtown Raleigh, Wendell, Knightdale, Rocky Mount,Wilson,and Wake Forest.

    Key differentiators about GSK and Zebulon:

    • Our commitment to inclusion is seen as a critical advantage of ours

    • Our focus on cultivating a positive work environment that cares for our employees

    • Demonstrated opportunities for continued career growth driven by individual ambition

    • Leaders that care about their teams and growth of both individuals and the company

    • A priority focus onSafety and Quality

    • CleanandGMP compliant work environment

    • Onsite cafeteria

    • Onsite gym

    • Temperature-controlledclimate

    • Licensed,onsite Health & Wellness clinic

    #LI-GSK

    Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

    Why GSK?

    Uniting science, technology and talent to get ahead of disease together.

    GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases - to impact health at scale.

    People and patients around the world count on the medicines and vaccines we make, so we're committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

    If you require an accommodation or other assistance to apply for a job at GSK, please contact the appropriate Recruitment Staff by emailing us at -usrecruitment.adjustments@gsk.com

    GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

    Important notice to Employment businesses/ Agencies

    GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

    Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/


    What GlaxoSmithKline employees say

    Pay

    Benefits

    Hours and flexibility

    Workplace

    Get the full story on Breakroom


    GlaxoSmithKline logo

    About GlaxoSmithKline

    Sourced by ZipRecruiter

    GlaxoSmithKline is a globally recognized pharmaceutical and healthcare company based in Philadelphia, PA, USA. Originated from a merger between Glaxo Wellcome and SmithKline Beecham in 2000, the company excels in the pharmaceutical industry and holds a leading position in making medicines, vaccines, and consumer healthcare products. GSK's mission is to improve the quality of human life by enabling people to do more, feel better, and live longer. They adhere to core values of transparency, integrity, respect for people, and patient-focus, reflecting in their endeavors to conduct research and deliver innovative healthcare solutions to patients and consumers worldwide.

    Industry

    Scientific research and development services

    Company size

    10,000+ Employees

    Headquarters location

    Philadelphia, PA, US