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Senior Python Engineer Jobs in Chesterfield, MO (NOW HIRING)

Sr. Software Engineer

Hazelwood, MO

$113K - $149K/yr

The Senior Software Engineer works within established architectural frameworks, enhances CI/CD and ... Experience developing solutions using Python, including scripting, automation, or data processing ...

Sr. Software Engineer

Hazelwood, MO

$115K - $152K/yr

The Senior Software Engineer works within established architectural frameworks, enhances CI/CD and ... Experience developing solutions using Python, including scripting, automation, or data processing ...

Sr. Software Engineer

Hazelwood, MO · On-site

$113K - $149K/yr

The Senior Software Engineer works within established architectural frameworks, enhances CI/CD and ... Experience developing solutions using Python, including scripting, automation, or data processing ...

Senior Industrial Engineer Company: The Boeing Company The Boeing Defense, Space & Security (BDS ... Handson technical mindset: experience with at least one analytical or scripting tool (e.g., Python ...

Senior Industrial Engineer Company: The Boeing Company The Boeing Defense, Space & Security (BDS ... Handson technical mindset: experience with at least one analytical or scripting tool (e.g., Python ...

Senior Software Engineer

O Fallon, MO

$114K - $151K/yr

Title and Summary Senior Software Engineer Who is Mastercard? Mastercard is a global technology ... All About You -Proficiency and hands-on experience building agentic frameworks in Python/TypeScript ...

Senior Software Engineer

O Fallon, MO · On-site

$114K - $151K/yr

Title and Summary Senior Software Engineer Who is Mastercard? Mastercard is a global technology ... All About You Proficiency and hands-on experience building agentic frameworks in Python/TypeScript.

Senior DevSecOps Engineer

Berkeley, MO · On-site

$107K - $147K/yr

Senior DevSecOps Engineer Company: The Boeing Company The Boeing Company is currently seeking a ... or Python * Experience with cloud platforms * Experience with Agile software development and ...

Senior DevSecOps Engineer

Berkeley, MO · On-site

$107K - $147K/yr

Senior DevSecOps Engineer Company: The Boeing Company The Boeing Company is currently seeking a ... or Python * Experience with cloud platforms * Experience with Agile software development and ...

Senior DevSecOps Engineer

Berkeley, MO · On-site

$107K - $147K/yr

Senior DevSecOps Engineer Company: The Boeing Company The Boeing Company is currently seeking a ... or Python * Experience with cloud platforms * Experience with Agile software development and ...

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Senior Python Engineer information

See Chesterfield, MO salary details

$54.4K

$140.5K

$193K

How much do senior python engineer jobs pay per year?

As of Jun 19, 2026, the average yearly pay for senior python engineer in Chesterfield, MO is $140,520.00, according to ZipRecruiter salary data. Most workers in this role earn between $120,300.00 and $161,800.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Senior Python Engineer, and why are they important?

To thrive as a Senior Python Engineer, you need expert knowledge of Python programming, software architecture, and experience with web frameworks, supported by a degree in computer science or related field. Familiarity with tools like Django, Flask, REST APIs, Docker, and version control systems such as Git is typically required, along with possible certifications in cloud technologies or Python itself. Strong problem-solving abilities, leadership, and effective communication skills help you lead teams and collaborate across departments. These skills ensure robust, scalable software solutions and foster innovation and efficiency within development projects.

What does a Senior Python Engineer do?

A Senior Python Engineer is an experienced software developer who specializes in designing, developing, and maintaining applications using the Python programming language. They often take on leadership roles within development teams, contribute to architectural decisions, and mentor junior engineers. Senior Python Engineers work on complex projects, ensure code quality, and help implement best practices to improve efficiency and reliability. Their work may span back-end development, data engineering, automation, and integrating with other technologies.

What are the common challenges Senior Python Engineers face when leading projects, and how can they effectively address them?

Senior Python Engineers often encounter challenges such as balancing hands-on coding with overseeing project architecture, mentoring junior developers, and ensuring code quality across the team. Effectively addressing these challenges involves strong communication, setting clear coding standards, and fostering a collaborative environment through regular code reviews and knowledge-sharing sessions. Staying updated on best practices and leveraging automation tools for testing and deployment can also help streamline workflows and maintain high-quality deliverables.
What are popular job titles related to Senior Python Engineer jobs in Chesterfield, MO? For Senior Python Engineer jobs in Chesterfield, MO, the most frequently searched job titles are:
What cities near Chesterfield, MO are hiring for Senior Python Engineer jobs? Cities near Chesterfield, MO with the most Senior Python Engineer job openings:
Sr. Software Engineer

$113K - $149K/yr

Other

Medical, Dental, Vision, Life, Retirement

Posted 20 days ago


Job description

As a member of the R&D organization responsible for creating software for the development of innovative in vitro diagnostic solutions, the Senior Software Engineer contributes to the design and delivery of scalable, cloud-native software solutions by implementing modern software development practices, including microservices architecture, CI/CD, and infrastructure as code. The Senior Software Engineer works within established architectural frameworks, enhances CI/CD and infrastructure as code solutions, and develops reliable data pipelines and governance practices. The Senior Software Engineer collaborates with cross-functional teams—including data engineering, product management, and architecture—to translate requirements into well-engineered solutions, uphold governance and security standards, and drive continuous improvement through code reviews, prototyping, and technology evaluation.

Primary Duties

  • Contributes to the design and implementation of multi-tier, distributed, and event-driven systems using cloud-native services and modern design patterns.

  • Implements infrastructure as code (IaC) solutions using AWS CloudFormation, containerized applications (Docker/Kubernetes), and automated deployment workflows.

  • Designs and develops microservices-based applications that leverage AWS/ECS/EKS to ensure scalability, security, and resilience.

  • Designs and develops data pipelines using AWS Lambda, Glue, and other AWS services, following operational standards for availability, performance, and disaster recovery.

  • Designs and develops RESTful APIs and integrates them with internal and external systems.

  • Designs and implements data storage solutions, including data lakes and warehouses that enable analytic and operational workloads.

  • Applies data governance practices—such as data quality, lineage, and security—within the systems and pipelines developed.

  • Implements integration strategies, APIs, and real-time/stream data solutions to ensure reliable and scalable data flows.

  • Contributes to technical design discussions and ensures solutions align with system engineering and architectural guidance.

  • Produces and maintains high-quality system designs, technical documentation, and implementation specifications.

  • Participates in design reviews, code reviews, and pair programming sessions to share knowledge and promote modern development practices.

  • Evaluates new technologies, tools, and frameworks, providing recommendations that support technical excellence and business needs.

  • Works closely with multidisciplinary teams to translate business requirements into technical designs and implementation plans.

  • Collaborates with cross-functional teams to integrate and optimize processes across teams.

  • Participates in proof-of-concept efforts by developing prototypes that validate design assumptions and accelerate solution delivery.

  • Performs other duties as assigned.

Qualifications

Required Education, Training, and Experience

  • Bachelor’s degree in Computer Science, Data Engineering, Software Engineering, Biology, Microbiology, Clinical Laboratory Science, Biomedical Engineering, or a related technical or scientific field

  • 7+ years of full stack development experience, including Java and modern web development frameworks such as Angular Suite.

  • Experience with AWS EC2, S3, Lambda Functions, ECS, EKS, RDS.

  • Proven experience with AWS integration/production systems using multiple managed services.

  • Solid grasp of security, compliance, and privacy fundamentals (least privilege, key management, network segmentation).

  • Experience developing and maintaining APIs or serverless patterns.

  • Influence and Code – Terraform (preferred) or AWS CDK/CloudFormation.

  • Implementation strategies for data integration.

  • Strong communication and collaboration skills.

  • Demonstrated architectural design patterns and automated quality gates to improve code health, reduce defects, and accelerate development.

  • Experience with relational databases (PostgreSQL, Oracle, etc.), advanced SQL.

Preferred Education, Training, and Experience

  • Compliance experience (e.g., HIPAA, SOX, ISO 13485, 21 CFR, or other related SDLC concepts).

  • Experience developing solutions using Python, including scripting, automation, or data processing workflows.

  • Automated unit and integration E2E testing framework (PyUnit, Selenium, etc.).

Knowledge, Skills, and Abilities

  • Acting with Honor and Being Open – Upholds and reflects bioMérieux’s ethical principles and values.

  • Intellectual Honesty/Openness – Applies problem-solving to complex business challenges.

  • Building Relationships – Demonstrates effective verbal and written communication skills.

  • Creating the New…and Different – Influences change and persuades others to adopt new ideas, behaviors, or processes.

  • Understanding the Business – Demonstrates critical thinking, adaptability, time management, communication, problem-solving, and digital literacy.

  • Intermediate proficiency: applies skills independently in most situations; handles moderately complex tasks with occasional guidance.

  • Skilled in MS Office tools including Outlook, Teams, Word, and Excel.

Working Conditions

  • Ability to remain in a stationary position for prolonged periods.

  • Travel required: 5% (including international travel).

  • Lifting required: No.

  • Other physical requirements: No.

  • Typical office setting with hybrid schedule ( 2 WFH, 3 days in office per week)

The estimated salary range for this role is between $82,000-$115,000. This role is eligible to receive a variable annual bonus based on company, team, and individual performance per bioMerieux’s bonus program. This range may differ from ranges offered for similar positions elsewhere in the country given differences in cost of living. Actual compensation within this range is determined based on the successful candidate’s experience and will be presented in writing at the time of the offer.

In addition, bioMérieux offers a competitive Total Rewards package that may include:

· A choice of medical (including prescription), dental, and vision plans providing nationwide coverage and telemedicine options

· Company-Provided Life and Accidental Death Insurance

· Short and Long-Term Disability Insurance

· Retirement Plan including a generous non-discretionary employer contribution and employer match.

· Adoption Assistance

· Wellness Programs

· Employee Assistance Program

· Commuter Benefits

· Various voluntary benefit offerings

· Discount programs

· Parental leaves

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