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Senior Python Engineer Jobs in Chesterfield, MO (NOW HIRING)

Senior Automation Engineer

Saint Louis, MO · Hybrid

$101K - $132K/yr

Evaluate, select, and implement Python libraries, testing tools, and supporting frameworks to ... As an experienced Senior Automation Engineer ,you will have the ability to share new ideas and ...

Senior Blockchain Developer

Chesterfield, MO · Hybrid

$54 - $71.25/hr

Senior Blockchain Developer Location: Chicago, IL, USA- Hybrid Duration: 12+ Month Contract ... Cryptography, GoLang, Java, NodeJs, Python, SDLC, Spring Boot Must have 10+ yrs of Blockchain ...

Sr Developer

O Fallon, MO · On-site

$51 - $67.25/hr

Position : Sr Developer Location : O FALLON MO (Remote 2 Months) the Oniste JD Spark with Scala • ... or python • Should have good working experience/knowledge in SQL • Should have good ...

Sr. Scala Developer

Saint Louis, MO

$53 - $70/hr

Louis, Missouri 08-03-2015 Senior Scala Developer w/hands-on experience writing Scala architecture on OS X and AWS models -- experience coding in Clojure, Java, and/or Python also a plus. Client is ...

Senior Storage Engineer Location: Arnold, MO (On Customer Site) Clearance: TS/SCI Citizenship: US ... PowerShell/Python scripting experience. * Experience leveraging scripts to audit and enforce ...

Senior Storage Engineer Location: Arnold, MO (On Customer Site) Clearance: TS/SCI Citizenship: US ... PowerShell/Python scripting experience. * Experience leveraging scripts to audit and enforce ...

Senior Data Engineer

Saint Louis, MO · On-site

$103K - $140K/yr

The Senior Data Engineer is responsible for architecting, implementing, and maintaining scalable ... Streamline data workflows using Python, JSON, Composer, and Airflow, while proactively monitoring ...

Senior Data Engineer

Saint Louis, MO · Hybrid

$103K - $140K/yr

The Senior Data Engineer is responsible for architecting, implementing, and maintaining scalable ... Streamline data workflows using Python, JSON, Composer, and Airflow, while proactively monitoring ...

Sr. Software Engineer

Hazelwood, MO

$115K - $152K/yr

The Senior Software Engineer works within established architectural frameworks, enhances CI/CD and ... Experience developing solutions using Python, including scripting, automation, or data processing ...

Sr. Software Engineer

Hazelwood, MO · On-site

$115K - $152K/yr

The Senior Software Engineer works within established architectural frameworks, enhances CI/CD and ... Experience developing solutions using Python, including scripting, automation, or data processing ...

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Senior Python Engineer information

See Chesterfield, MO salary details

$54.4K

$140.5K

$193K

How much do senior python engineer jobs pay per year?

As of Jun 19, 2026, the average yearly pay for senior python engineer in Chesterfield, MO is $140,520.00, according to ZipRecruiter salary data. Most workers in this role earn between $120,300.00 and $161,800.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Senior Python Engineer, and why are they important?

To thrive as a Senior Python Engineer, you need expert knowledge of Python programming, software architecture, and experience with web frameworks, supported by a degree in computer science or related field. Familiarity with tools like Django, Flask, REST APIs, Docker, and version control systems such as Git is typically required, along with possible certifications in cloud technologies or Python itself. Strong problem-solving abilities, leadership, and effective communication skills help you lead teams and collaborate across departments. These skills ensure robust, scalable software solutions and foster innovation and efficiency within development projects.

What does a Senior Python Engineer do?

A Senior Python Engineer is an experienced software developer who specializes in designing, developing, and maintaining applications using the Python programming language. They often take on leadership roles within development teams, contribute to architectural decisions, and mentor junior engineers. Senior Python Engineers work on complex projects, ensure code quality, and help implement best practices to improve efficiency and reliability. Their work may span back-end development, data engineering, automation, and integrating with other technologies.

What are the common challenges Senior Python Engineers face when leading projects, and how can they effectively address them?

Senior Python Engineers often encounter challenges such as balancing hands-on coding with overseeing project architecture, mentoring junior developers, and ensuring code quality across the team. Effectively addressing these challenges involves strong communication, setting clear coding standards, and fostering a collaborative environment through regular code reviews and knowledge-sharing sessions. Staying updated on best practices and leveraging automation tools for testing and deployment can also help streamline workflows and maintain high-quality deliverables.
What are popular job titles related to Senior Python Engineer jobs in Chesterfield, MO? For Senior Python Engineer jobs in Chesterfield, MO, the most frequently searched job titles are:
What cities near Chesterfield, MO are hiring for Senior Python Engineer jobs? Cities near Chesterfield, MO with the most Senior Python Engineer job openings:
Senior Associate Full Stack Engineer

Senior Associate Full Stack Engineer

Mastech Digital

Saint Louis, MO • Remote

$55 - $60/hr

Full-time, Contractor

Medical, Dental, Vision, Life, Retirement

Posted 9 days ago


Job description

Mastech Digital provides digital and mainstream technology staff as well as Digital Transformation Services for all American Corporations. We are currently seeking a Senior Associate Full Stack Engineer for our client in the Professional Services domain. We value our professionals, providing comprehensive benefits and the opportunity for growth. This is a Contract position, and the client is looking for someone to start immediately.

Duration: 6 Months Contract

Location: Remote (St. Louis, MO)

Salary: $55.00-$60.00/Hourly

Role: Senior Associate Full Stack Engineer

Primary Skills: Python

Role Description: The Senior Associate Full Stack Engineer must have 3+ years of experience. For this role, you must be a highly skilled Full Stack Engineer with deep expertise in building secure, scalable, and cloud-native applications. This role demands hands-on experience with modern frameworks, cloud platforms, and DevSecOps practices.

Education:

- Bachelor's Degree or Equivalent Work Experience

Year of Experience:

- 3+ years

Principal Responsibilities:

- Design and implement scalable, secure, and cloud-native software applications using Python, Django REST Framework, FastAPI, React, and Next.js within microservices architecture.

- Develop and maintain REST APIs and integrate with OIDC/OAuth-based authentication systems, ensuring compliance with advanced security concepts for apps in Azure and Entra ID cloud-native app security.

- Lead the deployment and orchestration of containerized applications using Docker, Helm, and Kubernetes, with a focus on developer-centric Kubernetes practices.

- Develop and manage CI/CD pipelines using GitHub Actions, incorporating automated testing, security scanning, and deployment workflows.

- Package and distribute Python applications using modern Python packaging standards and tools.

- Stay current with emerging technologies, including GenAI and LLMs, and contribute to innovative initiatives.

- Act with integrity, professionalism, and personal responsibility to uphold the firm’s respectful and courteous work environment.

Qualifications:

- Minimum of 3 years of full-stack development experience with demonstrated expertise in Python, React, including frameworks like Django REST Framework, and FastAPI.

- Bachelor’s degree in Computer Science, Software Engineering, or a related field.

- Proven experience building and securing cloud-native applications on Azure or GCP, with deep understanding of OIDC, OAuth, and Entra ID security models.

- Proficiency in containerization and orchestration using Docker, Helm, and Kubernetes, especially in developer-focused environments.

- Strong command of CI/CD pipelines using GitHub Actions, and version control with Git.

- Hands-on experience with scripting and automation using Bash, and PowerShell,

- Solid understanding of microservices architecture, REST API design, and Python packaging best practices.

- Familiarity with advanced application security in cloud environments, including threat modeling and secure deployment patterns.

- Experience with GenAI and LLMs is a plus.

- Strong verbal/written communication, problem solving, analytical and independent judgment skills to support an environment driven by customer service and teamwork.

- Ability to positively influence, mentor and be a credible source of knowledge to less experienced team members

Education: Bachelor’s degree in Computer Science, Software Engineering, or relevant field

Experience: Minimum 3+ years of experience

Relocation: This position will not cover relocation expenses

Travel: No

Local Preferred: Yes

Note: Must be able to work on a W2 basis (No C2C)

Recruiter Name: Kajal Vatsa

Recruiter Phone: 484-331-9666

Benefits:

We have various coverages and additional benefits to choose from:

- Medical, Dental (Including Ortho) & Vision Insurance (Option to Enroll).

- Paid Leaves (Wherever applicable).

- Life & Disability Coverage (Upon eligibility).

- 401K Option, Education Assistance Program and more.

Mastech Digital is an Equal Opportunity Employer - All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or protected veteran status.

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