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Senior Python Engineer Jobs in Chesterfield, MO (NOW HIRING)

Arka Infotech Inc

Sr. Scala Developer

Saint Louis, MO

$53 - $70/hr

Louis, Missouri 08-03-2015 Senior Scala Developer w/hands-on experience writing Scala architecture on OS X and AWS models -- experience coding in Clojure, Java, and/or Python also a plus. Client is ...

Futran Tech Solutions Pvt. Ltd.

Sr Developer

O Fallon, MO · On-site

$51 - $67.25/hr

Position : Sr Developer Location : O FALLON MO (Remote 2 Months) the Oniste JD Spark with Scala • ... or python • Should have good working experience/knowledge in SQL • Should have good ...

Intellectix

Senior Storage Engineer

Arnold, MO · On-site

Senior Storage Engineer Location: Arnold, MO (On Customer Site) Clearance: TS/SCI Citizenship: US ... PowerShell/Python scripting experience. * Experience leveraging scripts to audit and enforce ...

Intellectix

Senior Storage Engineer

Arnold, MO

Senior Storage Engineer Location: Arnold, MO (On Customer Site) Clearance: TS/SCI Citizenship: US ... PowerShell/Python scripting experience. * Experience leveraging scripts to audit and enforce ...

bioMerieux

Sr. Software Engineer

Hazelwood, MO · On-site

$115K - $152K/yr

The Senior Software Engineer works within established architectural frameworks, enhances CI/CD and ... Experience developing solutions using Python, including scripting, automation, or data processing ...

bioMérieux

Sr. Software Engineer

Hazelwood, MO · On-site

$115K - $152K/yr

The Senior Software Engineer works within established architectural frameworks, enhances CI/CD and ... Experience developing solutions using Python, including scripting, automation, or data processing ...

bioMerieux Inc.

Sr. Software Engineer

Hazelwood, MO · On-site

$113K - $149K/yr

The Senior Software Engineer works within established architectural frameworks, enhances CI/CD and ... Experience developing solutions using Python, including scripting, automation, or data processing ...

BioFire Diagnostics

Sr. Software Engineer

Hazelwood, MO

$115K - $152K/yr

The Senior Software Engineer works within established architectural frameworks, enhances CI/CD and ... Experience developing solutions using Python, including scripting, automation, or data processing ...

Biomerieux

Sr. Software Engineer

Hazelwood, MO · On-site

$113K - $149K/yr

The Senior Software Engineer works within established architectural frameworks, enhances CI/CD and ... Experience developing solutions using Python, including scripting, automation, or data processing ...

MasterCard

Senior Software Engineer

O Fallon, MO · On-site

$114K - $151K/yr

Title and Summary Senior Software Engineer Who is Mastercard? Mastercard is a global technology ... All About You Proficiency and hands-on experience building agentic frameworks in Python/TypeScript.

MasterCard

Senior Software Engineer

O Fallon, MO · On-site

$114K - $151K/yr

Title and Summary Senior Software Engineer Who is Mastercard? Mastercard is a global technology ... All About You Proficiency and hands-on experience building agentic frameworks in Python/TypeScript.

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All JobsPython Engineer JobsSenior Python Engineer JobsSenior Python Engineer Jobs in Chesterfield, MO

Senior Python Engineer information

See Chesterfield, MO salary details

$54.4K

$140.5K

$193K

How much do senior python engineer jobs pay per year?

As of Jul 13, 2026, the average yearly pay for senior python engineer in Chesterfield, MO is $140,520.00, according to ZipRecruiter salary data. Most workers in this role earn between $120,300.00 and $161,800.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Senior Python Engineer, and why are they important?

To thrive as a Senior Python Engineer, you need expert knowledge of Python programming, software architecture, and experience with web frameworks, supported by a degree in computer science or related field. Familiarity with tools like Django, Flask, REST APIs, Docker, and version control systems such as Git is typically required, along with possible certifications in cloud technologies or Python itself. Strong problem-solving abilities, leadership, and effective communication skills help you lead teams and collaborate across departments. These skills ensure robust, scalable software solutions and foster innovation and efficiency within development projects.

What does a Senior Python Engineer do?

A Senior Python Engineer is an experienced software developer who specializes in designing, developing, and maintaining applications using the Python programming language. They often take on leadership roles within development teams, contribute to architectural decisions, and mentor junior engineers. Senior Python Engineers work on complex projects, ensure code quality, and help implement best practices to improve efficiency and reliability. Their work may span back-end development, data engineering, automation, and integrating with other technologies.

What are the common challenges Senior Python Engineers face when leading projects, and how can they effectively address them?

Senior Python Engineers often encounter challenges such as balancing hands-on coding with overseeing project architecture, mentoring junior developers, and ensuring code quality across the team. Effectively addressing these challenges involves strong communication, setting clear coding standards, and fostering a collaborative environment through regular code reviews and knowledge-sharing sessions. Staying updated on best practices and leveraging automation tools for testing and deployment can also help streamline workflows and maintain high-quality deliverables.
What cities near Chesterfield, MO are hiring for Senior Python Engineer jobs? Cities near Chesterfield, MO with the most Senior Python Engineer job openings:
Senior Python Engineer jobs near you
Senior Electronics Engineer

Senior Electronics Engineer

DeepSight Technology Inc.

Saint Louis, MO

$100K - $140K/yr

Full-time

Medical, Dental, Vision, Retirement

Re-posted 17 days ago

Job description

Are you an experienced electrical engineer who wants to contribute to interesting new projects and solve complex new problems? Would you like to support the improvement of medical-grade imaging tools and diagnostics? That's exactly what you'll be doing as a full-time Senior Electronics Engineer with DeepSight Technology Inc.!

When you join our St Louis, MO team, you'll ensure we create quality components that comply with medical regulations. We're offering a competitive salary of $100,000 - $140,000/year and terrific benefits like:

  • Stock options
  • Medical
  • Dental
  • Vision
  • 401(k) retirement plan

Interested? Keep reading to learn more!


ROLE EXPECTATIONS

Your goal as our Senior Electronics Engineer is to design, create, and debug printed circuit boards (PCBs) for complex medical imaging purposes. These are extremely important components, and you'll oversee the entire hardware lifecycle to ensure the boards comply with all technical specifications and medical-grade requirements. You'll design boards, run SPICE simulations, manage fabrication and assembly activities, and lead V&V (verification and validation) processes to ensure all circuit boards are up to par.

If you observe any issues with the boards, you'll use various lab instruments to troubleshoot and resolve the problem. You'll manage our inventory, document technical information, submit formal verification reports, and characterize microelectronic systems utilizing FPGAs and microcontrollers. Your strict attention to detail and strategic problem-solving skills will ensure every board is ready for medical-grade purposes.


OUR IDEAL SENIOR ELECTRONICS ENGINEER

  • BS in electrical engineering or a related technical field
  • 5+ years of industry experience, preferably in a regulated field such as medical, automotive, or aerospace
  • Hands-on experience with SPICE or a similar circuit simulation tool
  • Proven experience working with FPGAs and/or Microcontrollers
  • Advanced experience with high-speed oscilloscopes, spectrum analyzers, and data acquisition boards
  • Expert-level proficiency in CAD layout tools, specifically Altium Designer
  • Proficiency in Python for hardware automation and data collection

HELP US SUPPORT THE FUTURE OF MEDICAL IMAGING!

DeepSight Technology Inc. is an early-stage, pre-commercial medical device company with a vision for Physical AI -scaling advanced multimodal sensing technologies so clinicians can see more, sense more, and guide procedures with greater precision and confidence. Our vision starts with developing a breakthrough platform combining acousto-optic sensing technology and ultrasound imaging.

DeepSight is seeking dedicated, talented team members as we scale. We offer a collaborative, team-oriented environment along with competitive compensation and generous benefits

Become the newest member of our talented engineering team by completing our short initial application today!

Apply