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Senior Python Engineer Jobs in Chesterfield, MO (NOW HIRING)

Mastercard, Inc.

Senior Software Engineer

O Fallon, MO · On-site

$114K - $151K/yr

Title and Summary Senior Software Engineer Who is Mastercard? Mastercard is a global technology ... Strict Must-Haves (Non-Negotiable) • Python - Proven experience building and operationalizing ...

Arka Infotech Inc

Sr. Scala Developer

Saint Louis, MO · On-site

$53 - $70/hr

Louis, Missouri 08-03-2015 Senior Scala Developer w/hands-on experience writing Scala architecture on OS X and AWS models -- experience coding in Clojure, Java, and/or Python also a plus. Client is ...

Futran Tech Solutions Pvt. Ltd.

Sr Developer

O Fallon, MO · On-site

$51 - $67.25/hr

Position : Sr Developer Location : O FALLON MO (Remote 2 Months) the Oniste JD Spark with Scala • ... or python • Should have good working experience/knowledge in SQL • Should have good ...

Intellectix

Senior Storage Engineer

Arnold, MO · On-site

Senior Storage Engineer Location: Arnold, MO (On Customer Site) Clearance: TS/SCI Citizenship: US ... PowerShell/Python scripting experience. * Experience leveraging scripts to audit and enforce ...

Intellectix

Senior Storage Engineer

Arnold, MO · On-site

Senior Storage Engineer Location: Arnold, MO (On Customer Site) Clearance: TS/SCI Citizenship: US ... PowerShell/Python scripting experience. * Experience leveraging scripts to audit and enforce ...

bioMerieux

Sr. Software Engineer

Hazelwood, MO · On-site

$115K - $152K/yr

The Senior Software Engineer works within established architectural frameworks, enhances CI/CD and ... Experience developing solutions using Python, including scripting, automation, or data processing ...

bioMérieux

Sr. Software Engineer

Hazelwood, MO · On-site

$115K - $152K/yr

The Senior Software Engineer works within established architectural frameworks, enhances CI/CD and ... Experience developing solutions using Python, including scripting, automation, or data processing ...

BioFire Diagnostics

Sr. Software Engineer

Hazelwood, MO · On-site

$115K - $152K/yr

The Senior Software Engineer works within established architectural frameworks, enhances CI/CD and ... Experience developing solutions using Python, including scripting, automation, or data processing ...

Biomerieux

Sr. Software Engineer

Hazelwood, MO · On-site

$113K - $149K/yr

The Senior Software Engineer works within established architectural frameworks, enhances CI/CD and ... Experience developing solutions using Python, including scripting, automation, or data processing ...

MasterCard

Senior Software Engineer

O Fallon, MO · On-site

$114K - $151K/yr

Title and Summary Senior Software Engineer Who is Mastercard? Mastercard is a global technology ... All About You Proficiency and hands-on experience building agentic frameworks in Python/TypeScript.

MasterCard

Senior Software Engineer

O Fallon, MO

$114K - $151K/yr

Title and Summary Senior Software Engineer Who is Mastercard? Mastercard is a global technology ... All About You Proficiency and hands-on experience building agentic frameworks in Python/TypeScript.

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All JobsPython Engineer JobsSenior Python Engineer JobsSenior Python Engineer Jobs in Chesterfield, MO

Senior Python Engineer information

See Chesterfield, MO salary details

$54.4K

$140.5K

$193K

How much do senior python engineer jobs pay per year?

As of Jul 10, 2026, the average yearly pay for senior python engineer in Chesterfield, MO is $140,520.00, according to ZipRecruiter salary data. Most workers in this role earn between $120,300.00 and $161,800.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Senior Python Engineer, and why are they important?

To thrive as a Senior Python Engineer, you need expert knowledge of Python programming, software architecture, and experience with web frameworks, supported by a degree in computer science or related field. Familiarity with tools like Django, Flask, REST APIs, Docker, and version control systems such as Git is typically required, along with possible certifications in cloud technologies or Python itself. Strong problem-solving abilities, leadership, and effective communication skills help you lead teams and collaborate across departments. These skills ensure robust, scalable software solutions and foster innovation and efficiency within development projects.

What does a Senior Python Engineer do?

A Senior Python Engineer is an experienced software developer who specializes in designing, developing, and maintaining applications using the Python programming language. They often take on leadership roles within development teams, contribute to architectural decisions, and mentor junior engineers. Senior Python Engineers work on complex projects, ensure code quality, and help implement best practices to improve efficiency and reliability. Their work may span back-end development, data engineering, automation, and integrating with other technologies.

What are the common challenges Senior Python Engineers face when leading projects, and how can they effectively address them?

Senior Python Engineers often encounter challenges such as balancing hands-on coding with overseeing project architecture, mentoring junior developers, and ensuring code quality across the team. Effectively addressing these challenges involves strong communication, setting clear coding standards, and fostering a collaborative environment through regular code reviews and knowledge-sharing sessions. Staying updated on best practices and leveraging automation tools for testing and deployment can also help streamline workflows and maintain high-quality deliverables.
What cities near Chesterfield, MO are hiring for Senior Python Engineer jobs? Cities near Chesterfield, MO with the most Senior Python Engineer job openings:
Senior Python Engineer jobs near you

Senior Software Engineer

Freedom Technology Solutions Group

Saint Louis, MO • Remote

$119K - $157K/yr

Other

Re-posted 21 days ago

Job description

Freedom Technology Solutions Group is seeking a Software Developer to support our client's intelligence analysis products and capabilities. This position involves providing software development capabilities to enhance existing and emerging client capabilities, including design and development, modernization of existing applications and services, and operations and sustainment. The role focuses on driving the client's adaptation of higher levels of automation and operational efficiency through agile development methodologies, rapid prototyping, and modern technology stacks. 

The Senior Software Developer provides comprehensive knowledge across multiple backend and cloud technologies, leading major assignments and guiding project outcomes. Functions as a technical expert and may lead teams of developers. 

Responsibilities: 

  • Lead the design, development, and deployment of enterprise-scale backend services.
  • Architect and optimize secure DevSecOps pipelines and automated testing frameworks.
  • Direct the migration, scaling, and modernization of applications in AWS environments.
  • Drive geospatial solution integration across enterprise applications.
  • Define technical standards, coding guidelines, and best practices.
  • Supervise development teams and provide technical mentorship.
  • Evaluate performance results and recommend project-wide improvements.
  • Support proposal writing, technical white papers, and client briefings. 

Key Technologies:

  • Linux
  • Java, JavaScript, Python
  • Containerization (Docker, OpenShift, Kubernetes, ...)
  • AWS Services
  • GitLab
  • Apache Spark, Glue, and other ETL processes/procedures
  • Data Types: Structured and Unstructured, Parquet, JSON, XML, etc. 

Required Qualifications:

  • Active security clearance TS/SCI (eligible for CI Poly).
  • 9-13 years of backend development experience.
  • Expert proficiency in Java, JavaScript, and/or Python.
  • Proven leadership in DevSecOps adoption and Agile/SAFe development frameworks.
  • Advanced AWS expertise, including architecture and deployment of containerized applications.
  • Deep experience with geospatial systems and enterprise integration.
  • Strong ability to plan, manage, and deliver complex technology assignments.
  • Using GitLab for code source repository and using GitLab CI/CD
  • Developing customized code, scripts, modules, macro procedures, or libraries for specialized spatial analysis functions using languages such as Python, Java, JavaScript, PHP, C, C++, C#, Perl, or similar
  • Experience working independently with clients or stakeholders to develop user stories for full-service consumer and business applications 

Desired Qualifications:

  • Experience with government and/or commercial imagery products, including SAR or related RADAR imaging technologies
  • Developing geospatial information systems (GIS) and working with open-source and proprietary geospatial formats
  • Using and developing common geospatial tools, data, and operating platforms such as:
    • Tools: Boundless Spatial suite, Remote View, PostGRES/PostGIS, Oracle Spatial, ArcGIS Desktop, ArcGIS Server, Image Server, File Geodatabases
    • Data Formats: KML, KMZ, NITF, TIFF, JPEG, GeoPDF, and similar geo-related formats and data structures
  • Abstracting new or legacy systems via standards-based APIs, including Open Geospatial Consortium standards
  • Developing terrain analysis visualization and algorithms
  • Developing automated detection algorithms
  • Experience with Argo Workflows 

Apply